Aliases for ANAPC16 Gene
External Ids for ANAPC16 Gene
Previous HGNC Symbols for ANAPC16 Gene
Previous GeneCards Identifiers for ANAPC16 Gene
GeneCards Summary for ANAPC16 Gene
ANAPC16 (Anaphase Promoting Complex Subunit 16) is a Protein Coding gene. Diseases associated with ANAPC16 include Cornea Cancer and Ideomotor Apraxia. Among its related pathways are Regulation of activated PAK-2p34 by proteasome mediated degradation and APC-Cdc20 mediated degradation of Nek2A.
UniProtKB/Swiss-Prot Summary for ANAPC16 Gene
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.