Aliases for AMZ2 Gene
External Ids for AMZ2 Gene
Previous GeneCards Identifiers for AMZ2 Gene
The protein encoded by this gene is a zinc metalloprotease that displays some activity against angiotensin-3. The encoded protein is inhibited by the aminopeptidase inhibitor amastatin, as well as by the general inhibitors o-phenanthroline and batimastat. Defects in this gene may be associated with lung tumorigenesis. [provided by RefSeq, Oct 2016]
GeneCards Summary for AMZ2 Gene
AMZ2 (Archaelysin Family Metallopeptidase 2) is a Protein Coding gene. Diseases associated with AMZ2 include Deafness, Autosomal Dominant 41 and Dubowitz Syndrome. Gene Ontology (GO) annotations related to this gene include metallopeptidase activity. An important paralog of this gene is AMZ1.
UniProtKB/Swiss-Prot Summary for AMZ2 Gene
Zinc metalloprotease. Exhibits activity against angiotensin-3 in vitro. Does not hydrolyze either neurogranin or angiotensin-2.