Aliases for AMY1C Gene
External Ids for AMY1C Gene
Previous HGNC Symbols for AMY1C Gene
Previous GeneCards Identifiers for AMY1C Gene
Amylases are secreted proteins that hydrolyze 1,4-alpha-glucoside bonds in oligosaccharides and polysaccharides, and thus catalyze the first step in digestion of dietary starch and glycogen. The human genome has a cluster of several amylase genes that are expressed at high levels in either salivary gland or pancreas. This gene encodes an amylase isoenzyme produced by the salivary gland. [provided by RefSeq, Jul 2008]
GeneCards Summary for AMY1C Gene
AMY1C (Amylase Alpha 1C) is a Protein Coding gene. Diseases associated with AMY1C include Stereotypic Movement Disorder and Avoidant Personality Disorder. Among its related pathways are Salivary secretion and Glycosaminoglycan metabolism. Gene Ontology (GO) annotations related to this gene include cation binding and alpha-amylase activity. An important paralog of this gene is AMY1A.
UniProtKB/Swiss-Prot Summary for AMY1C Gene
Calcium-binding enzyme that initiates starch digestion in the oral cavity (PubMed:12527308). Catalyzes the hydrolysis of internal (1->4)-alpha-D-glucosidic bonds, yielding a mixture of maltose, isomaltose, small amounts of glucose as well as small linear and branched oligosaccharides called dextrins (PubMed:12527308).