Aliases for AMT Gene
External Ids for AMT Gene
Previous GeneCards Identifiers for AMT Gene
This gene encodes one of four critical components of the glycine cleavage system. Mutations in this gene have been associated with glycine encephalopathy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
GeneCards Summary for AMT Gene
AMT (Aminomethyltransferase) is a Protein Coding gene. Diseases associated with AMT include Glycine Encephalopathy and Atypical Glycine Encephalopathy. Among its related pathways are One carbon pool by folate and Glyoxylate and dicarboxylate metabolism. Gene Ontology (GO) annotations related to this gene include transaminase activity and aminomethyltransferase activity. An important paralog of this gene is DMGDH.
UniProtKB/Swiss-Prot Summary for AMT Gene
The glycine cleavage system catalyzes the degradation of glycine.