Aliases for AMPH Gene
Aliases for AMPH Gene
External Ids for AMPH Gene
- HGNC: 471
- Entrez Gene: 273
- Ensembl: ENSG00000078053
- OMIM: 600418
- UniProtKB: P49418
Previous GeneCards Identifiers for AMPH Gene
- GC07M038069
- GC07M038130
- GC07M038164
- GC07M038196
- GC07M038389
- GC07M038423
- GC07M038307
- GC07M038442
- GC07M038464
- GC07M038479
- GC07M038492
- GC07M038506
- GC07M038518
- GC07M038530
- GC07M038548
Summaries for AMPH Gene
-
This gene encodes a protein associated with the cytoplasmic surface of synaptic vesicles. A subset of patients with stiff-man syndrome who were also affected by breast cancer are positive for autoantibodies against this protein. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences have not been determined. A pseudogene of this gene is found on chromosome 11.[provided by RefSeq, Nov 2010]
GeneCards Summary for AMPH Gene
AMPH (Amphiphysin) is a Protein Coding gene. Diseases associated with AMPH include Stiff-Person Syndrome and Limbic Encephalitis. Among its related pathways are Internalization of ErbB1 and Vesicle-mediated transport. Gene Ontology (GO) annotations related to this gene include phospholipid binding. An important paralog of this gene is BIN1.
UniProtKB/Swiss-Prot for AMPH Gene
-
May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for AMPH Gene
Genomics for AMPH Gene
GeneHancer (GH) Regulatory Elements for AMPH Gene
Promoters and enhancers for AMPH Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH07J038630 | Promoter/Enhancer | 1.8 | EPDnew Ensembl ENCODE | 650.7 | +0.3 | 267 | 1 | PKNOX1 NFIB FEZF1 ZNF335 GLIS2 EGR1 ZNF366 ZNF143 KLF7 EGR2 | AMPH GC07M038563 | |
| GH07J038429 | Promoter | 0.5 | EPDnew | 650.1 | +202.3 | 202304 | 0.1 | AMPH FAM183BP TRGV1 RN7SL83P | ||
| GH07J038463 | Enhancer | 0.5 | ENCODE | 55.7 | +168.0 | 167955 | 1 | STAT1 NFIC SMAD1 STAT2 BCL6B JUNB | AMPH FAM183BP RN7SL83P TRGV1 | |
| GH07J038334 | Enhancer | 1.6 | FANTOM5 Ensembl ENCODE dbSUPER | 9.2 | +295.2 | 295226 | 3.7 | HDGF PKNOX1 ARNT SIN3A ZNF2 YY1 POLR2B E2F8 ZNF143 ZNF263 | TRGV7 ENSG00000272908 TRGV5 TRGV5P STARD3NL AMPH TRGV6 TRG | |
| GH07J038433 | Enhancer | 0.3 | ENCODE | 41.9 | +197.6 | 197635 | 0.3 | CTCF | AMPH FAM183BP TRGV1 RN7SL83P |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around AMPH on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the AMPH gene promoter:
-
- AP-1
- p53
- CUTL1
- AP-2alpha isoform 2
- AP-2alpha
- AP-2alpha isoform 4
Regulatory Element Products
Genomic Locations for AMPH Gene
Genomic Locations for AMPH Gene
- chr7:38,383,694-38,631,567
- (GRCh38/hg38)
- Size:
- 247,874 bases
- Orientation:
- Minus strand
- chr7:38,423,297-38,671,167
- (GRCh37/hg19)
- Size:
- 247,871 bases
- Orientation:
- Minus strand
Genomic View for AMPH Gene
Genes around AMPH on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 7p14.1 by Entrez Gene
- 7p14.1 by HGNC
- 7p14.1 by Ensembl
AMPH Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for AMPH Gene
Proteins for AMPH Gene
-
Protein details for AMPH Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P49418-AMPH_HUMAN
- Recommended name:
- Amphiphysin
- Protein Accession:
- P49418
- A4D1X8
- A4D1X9
- O43538
- Q75MJ8
- Q75MK5
- Q75MM3
- Q8N4G0
Protein attributes for AMPH Gene
- Size:
- 695 amino acids
- Molecular mass:
- 76257 Da
- Quaternary structure:
-
- Heterodimer with BIN1. Binds SH3GLB1 and AP2A2 (By similarity). Interacts with AP2B1. Interacts with REPS1 and SGIP1; may be involved in clathrin-mediated endocytosis.
- Miscellaneous:
-
- Antibodies against AMPH are detected in patients with stiff-man syndrome, a rare disease of the central nervous system characterized by progressive rigidity of the body musculature with superimposed painful spasms.
Three dimensional structures from OCA and Proteopedia for AMPH Gene
Protein Expression for AMPH Gene
Post-translational modifications for AMPH Gene
Other Protein References for AMPH Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- R&D Systems Antibodies for AMPH (Amphiphysin/AMPH)
-
Custom Antibody ServicesOriGene Antibodies for AMPH
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- Invitrogen Antibodies for AMPH
- GeneTex AMPH Antibody for AMPH
-
Santa Cruz Biotechnology (SCBT) Antibodies for AMPH
Protein Products
-
OriGene Purified Proteins for AMPH
- Search Origene for MassSpec and Protein Over-expression Lysates for AMPH
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- Search GeneTex for Proteins for AMPH
Assay Products
-
Custom Assay ServicesOriGene ELISA Kits for AMPH
- Novus Biologicals ELISA Kits for AMPH
No data available for DME Specific Peptides for AMPH Gene
Domains & Families for AMPH Gene
Gene Families for AMPH Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Cancer-related genes
- Predicted intracellular proteins
Protein Domains for AMPH Gene
Suggested Antigen Peptide Sequences for AMPH Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for AMPH Gene
Function for AMPH Gene
Molecular function for AMPH Gene
- UniProtKB/Swiss-Prot Function:
- May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton.
- GENATLAS Biochemistry:
- amphiphysin,nerve terminal,synaptic vesicle associated antigen,involved in synaptic vesicle endocytosis in the nerve terminals,by binding to the coat protein adaptor
Phenotypes From GWAS Catalog for AMPH Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 9148966 |
| GO:0005543 | phospholipid binding | IDA | 22750946 |
Phenotypes for AMPH Gene
- MGI mutant phenotypes for AMPH:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for AMPH:
-
- Increased epidermal growth factor receptor (EGFR) surface abundance
- Negative genetic interaction between PTTG1-/- and PTTG1+/+
- Negative genetic interaction between BLM-/- and BLM+/+
- Decreased viability
- no effect
- Increased vaccinia virus (VACV) infection
- Synthetic lethal with Ras
- Decreased infection with West Nile virus (WNV)
- Decreased West Nile virus (WNV) infection
Animal Models for AMPH Gene
- MGI Knock Outs for AMPH:
-
- Amph Amph<tm1Pdc>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for AMPH
-
CRISPR Products
-
OriGene CRISPR knockouts for AMPH
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for AMPH
- genomics-online: gRNA clones - Search results for 112 available Amphiphysin gene related products
- Overview of 112 available Amphiphysin gene related products
- Applied Biological Materials CRISPR for AMPH
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for AMPH
- GenScript: Design CRISPR guide RNA sequences for AMPH
miRNA for AMPH Gene
- miRTarBase miRNAs that target AMPH
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for AMPH
- Browse OriGene Inhibitory RNA Products For AMPH
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- genomics-online: shRNA clones - Search results for 112 available Amphiphysin gene related products
- Overview of 112 available Amphiphysin gene related products
Clone Products
- Sino Biological Human cDNA Clone for AMPH
- VectorBuilder custom plasmid, inducible vectors for AMPH
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for AMPH
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for AMPH
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for AMPH
- Applied Biological Materials Clones for AMPH
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for AMPH
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for AMPH Gene
Localization for AMPH Gene
Subcellular locations from UniProtKB/Swiss-Prot for AMPH Gene
- Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| cytoskeleton | 5 |
| cytosol | 5 |
| nucleus | 2 |
| endosome | 2 |
| peroxisome | 1 |
| golgi apparatus | 1 |
- Cytosol (3)
- Plasma membrane (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005829 | cytosol | TAS | -- |
| GO:0005856 | cytoskeleton | IEA | -- |
| GO:0008021 | synaptic vesicle | TAS | 1628617 |
| GO:0015629 | actin cytoskeleton | TAS | 9182667 |
Pathways & Interactions for AMPH Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Vesicle-mediated transport | ||
| 2 | Endocytosis | ||
| 3 | Fc gamma R-mediated phagocytosis | ||
| 4 | Beta-Adrenergic Signaling |
.36
|
|
| 5 | Clathrin-mediated endocytosis | ||
Pathways by source for AMPH Gene
2 BioSystems pathways for AMPH Gene
3 Reactome pathways for AMPH Gene
2 KEGG pathways for AMPH Gene
1 Qiagen pathway for AMPH Gene
Interacting Proteins for AMPH Gene
Selected Interacting proteins:
P49418-AMPH_HUMAN
ENSP00000348602
for AMPH Gene via
IID
UniProtKB
MINT
STRING
GPS-Prot Interaction Network for AMPH
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006897 | endocytosis | TAS | 9182667 |
| GO:0007268 | chemical synaptic transmission | TAS | 9182667 |
| GO:0061024 | membrane organization | TAS | -- |
Transcripts for AMPH Gene
mRNA/cDNA for AMPH Gene
- (8) REFSEQ mRNAs :
- (10) Additional mRNA sequences :
- (82) Selected AceView cDNA sequences:
- (9) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000325590 3145 bps (uc003tgv.4)
- ENST00000356264 3418 bps (uc003tgu.4)
- ENST00000441628 1735 bps (uc064cye.1)
- ENST00000450124 665 bps (uc064cyh.1)
- ENST00000460887 430 bps (uc064cyf.1)
CRISPR Products
-
OriGene CRISPR knockouts for AMPH
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for AMPH
- genomics-online: gRNA clones - Search results for 112 available Amphiphysin gene related products
- Overview of 112 available Amphiphysin gene related products
- Applied Biological Materials CRISPR for AMPH
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for AMPH
- GenScript: Design CRISPR guide RNA sequences for AMPH
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for AMPH
- Browse OriGene Inhibitory RNA Products For AMPH
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for AMPH
- genomics-online: shRNA clones - Search results for 112 available Amphiphysin gene related products
- Overview of 112 available Amphiphysin gene related products
Clone Products
- Sino Biological Human cDNA Clone for AMPH
- VectorBuilder custom plasmid, inducible vectors for AMPH
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for AMPH
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for AMPH
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for AMPH
- Applied Biological Materials Clones for AMPH
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||||||||
| SP2: | |||||||||||||||||
| SP3: |
Expression for AMPH Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Brain (Nervous System)
-
Kidney (Urinary System)
- S-shaped Body Cells S-shaped Body
- S-shaped Body
-
Somite (Muscoskeletal System)
- Muscle Progenitor Cells Thoracic Ventrolateral Dermomyotome Lip
-
Skeletal Muscle (Muscoskeletal System)
- Muscle Progenitor Cells Thoracic Ventrolateral Dermomyotome Lip
- Bone (Muscoskeletal System)
- Dermis (Integumentary System)
- Fibroblasts
-
Ovary (Reproductive System)
mRNA differential expression in normal tissues according to GTEx for AMPH Gene
This gene is overexpressed in Brain - Frontal Cortex (BA9) (x6.5), Brain - Anterior cingulate cortex (BA24) (x5.8), Brain - Cortex (x5.4), and Brain - Cerebellar Hemisphere (x4.8).
This gene is overexpressed in Brain (41.4) and Frontal cortex (21.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for AMPH Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of AMPH Gene:
AMPHSOURCE GeneReport for Unigene cluster for AMPH Gene:
Hs.592182mRNA Expression by UniProt/SwissProt for AMPH Gene:
P49418-AMPH_HUMAN
Tissue specificity:
Neurons, certain endocrine cell types and spermatocytes.
Evidence on tissue expression from TISSUES for AMPH Gene
- Nervous system(5)
- Blood(2.3)
Primer Products
-
OriGene qPCR primer pairs for AMPH
- genomics-online: primer clones - Search results for 112 available Amphiphysin gene related products
- Overview of 112 available Amphiphysin gene related products
Gene Expression Assay Products
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for AMPH Gene
Orthologs for AMPH Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | AMPH 34 33 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | AMPH 34 33 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | AMPH 34 33 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | Amph 33 |
|
||
| mouse (Mus musculus) |
Mammalia | Amph 16 34 33 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | AMPH 34 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | AMPH 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | AMPH 34 33 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | AMPH 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | amph 33 |
|
||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.14350 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | amph 34 33 |
|
OneToOne | |
| zgc73193 33 |
|
||||
| fruit fly (Drosophila melanogaster) |
Insecta | Amph 34 35 |
|
OneToMany | |
| worm (Caenorhabditis elegans) |
Secernentea | amph-1 34 33 |
|
OneToMany | |
| F58G6.1 35 |
|
|
|||
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.3172 34 |
|
OneToMany |
- Species where no ortholog for AMPH was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Evolution for AMPH Gene
- ENSEMBL:
- Gene Tree for AMPH (if available)
- TreeFam:
- Gene Tree for AMPH (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for AMPH: view image
Paralogs for AMPH Gene
(2) SIMAP similar genes for AMPH Gene using alignment to 10 proteins:
- AMPH_HUMAN
- F5H533_HUMAN
- H0Y5S4_HUMAN
- H0Y7T8_HUMAN
- Q8NFL3_HUMAN
- Q8NFL4_HUMAN
- Q8NFL5_HUMAN
- Q8NFL6_HUMAN
- Q8NFL7_HUMAN
- Q8NFL8_HUMAN
Pseudogenes.org Pseudogenes for AMPH Gene
Variants for AMPH Gene
| SNP ID | Clin | Chr 07 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000001028 | -- | 38,530,019(-) | G/A | intron_variant | |
| rs1000008927 | -- | 38,446,256(-) | T/C | intron_variant | |
| rs1000010989 | -- | 38,491,506(-) | C/T | intron_variant | |
| rs1000021710 | -- | 38,479,117(-) | A/C | intron_variant | |
| rs1000047787 | -- | 38,397,687(-) | C/A | genic_downstream_transcript_variant, intron_variant |
Residual Variation Intolerance Score:
32.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
5.20;
69.83% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for AMPH Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- AMPH
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for AMPH Gene
Disorders for AMPH Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| stiff-person syndrome |
|
|
| limbic encephalitis |
|
|
| retinitis pigmentosa 9 |
|
|
| paraneoplastic polyneuropathy |
|
|
| breast cancer |
|
Search AMPH in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for AMPH
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for AMPH Gene
Publications for AMPH Gene
- Expression of amphiphysin I, an autoantigen of paraneoplastic neurological syndromes, in breast cancer. (PMID: 9513187) Floyd S … De Camilli P (Molecular medicine (Cambridge, Mass.) 1998) 3 4 22 58
- Primary structure of human amphiphysin, the dominant autoantigen of paraneoplastic stiff-man syndrome, and mapping of its gene (AMPH) to chromosome 7p13-p14. (PMID: 7757077) Yamamoto R … Kilimann MW (Human molecular genetics 1995) 3 4 22 58
- Autoimmunity in stiff-Man syndrome with breast cancer is targeted to the C-terminal region of human amphiphysin, a protein similar to the yeast proteins, Rvs167 and Rvs161. (PMID: 8076697) David C … De Camilli P (FEBS letters 1994) 3 4 22 58
- The synaptic vesicle-associated protein amphiphysin is the 128-kD autoantigen of Stiff-Man syndrome with breast cancer. (PMID: 8245793) De Camilli P … Kilimann MW (The Journal of experimental medicine 1993) 2 3 22 58
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 44 58
Products for AMPH Gene
- R&D Systems Antibodies for AMPH (Amphiphysin/AMPH)
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- Custom Antibody ServicesOriGene Antibodies for AMPH
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- OriGene Purified Proteins for AMPH
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- OriGene qPCR primer pairs for AMPH
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- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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- GenScript: Design CRISPR guide RNA sequences for AMPH
- Design optimal peptide antigens
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- Novus Biologicals Antibodies for AMPH
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- Novus Biologicals
- Novus Biologicals Tissue Microarrays
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- VectorBuilder custom plasmid, inducible vectors for AMPH
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for AMPH
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for AMPH
- antibodies-online: Search results for 135 available Amphiphysin Antibodies ranked by validation data
- Compare Top Amphiphysin Antibodies
- antibodies-online: Search results for available Amphiphysin related products ranked by validation data
- antibodies-online: Search results for 9 available Amphiphysin Proteins ranked by validation data
- Compare Top Amphiphysin Proteins
- Quality Products:
- GeneTex AMPH Antibody for AMPH
- Search GeneTex for Proteins for AMPH
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- Santa Cruz Biotechnology (SCBT) CRISPR for AMPH
- Horizon Cell Lines for AMPH
- genomics-online: cdna clones - Search results for 112 available Amphiphysin gene related products
- Overview of 112 available Amphiphysin gene related products
- orf clones - Search results for 112 available Amphiphysin gene related products
- Overview of 112 available Amphiphysin gene related products
- genomics-online: gRNA clones - Search results for 112 available Amphiphysin gene related products
- Overview of 112 available Amphiphysin gene related products
- genomics-online: primer clones - Search results for 112 available Amphiphysin gene related products
- Overview of 112 available Amphiphysin gene related products
- genomics-online: shRNA clones - Search results for 112 available Amphiphysin gene related products
- Overview of 112 available Amphiphysin gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for AMPH
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for AMPH
- GeneCopoeia miRNA 3'UTR Target clone products for AMPH
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for AMPH
Sources for AMPH Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio
- (169) Biorbyt