This gene encodes the receptor for the anti-Mullerian hormone (AMH) which, in addition to testosterone, results in male sex differentiation. AMH and testosterone are produced in the testes by different cells and have different effects. Testosterone promotes the development of male genitalia while the binding of AMH to the encoded receptor prevents the development of the mulleri... See more...

Aliases for AMHR2 Gene

Aliases for AMHR2 Gene

  • Anti-Mullerian Hormone Receptor Type 2 2 3 5
  • MISRII 2 3 4
  • MISR2 2 3 4
  • Muellerian Inhibiting Substance Type II Receptor 2 3
  • Anti-Muellerian Hormone Type II Receptor 3 4
  • Anti-Muellerian Hormone Type-2 Receptor 3 4
  • AMH Type II Receptor 3 4
  • MIS Type II Receptor 3 4
  • EC 2.7.11.30 4 51
  • AMHR 3 4
  • MRII 3 4
  • Mullerian Inhibiting Substance Type II Receptor 3
  • Anti-Mullerian Hormone Receptor, Type II 3
  • Anti-Mullerian Hormone Receptor Type II 2
  • AMHR2 5

External Ids for AMHR2 Gene

Previous GeneCards Identifiers for AMHR2 Gene

  • GC12P053823
  • GC12P053925
  • GC12P053534
  • GC12P052103
  • GC12P050858

Summaries for AMHR2 Gene

Entrez Gene Summary for AMHR2 Gene

  • This gene encodes the receptor for the anti-Mullerian hormone (AMH) which, in addition to testosterone, results in male sex differentiation. AMH and testosterone are produced in the testes by different cells and have different effects. Testosterone promotes the development of male genitalia while the binding of AMH to the encoded receptor prevents the development of the mullerian ducts into uterus and Fallopian tubes. Mutations in this gene are associated with persistent Mullerian duct syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Sep 2009]

GeneCards Summary for AMHR2 Gene

AMHR2 (Anti-Mullerian Hormone Receptor Type 2) is a Protein Coding gene. Diseases associated with AMHR2 include Persistent Mullerian Duct Syndrome, Types I And Ii and Persistent Mullerian Duct Syndrome. Among its related pathways are ALK2 signaling events and PEDF Induced Signaling. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is BMPR2.

UniProtKB/Swiss-Prot Summary for AMHR2 Gene

  • On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone.

No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for AMHR2 Gene

Genomics for AMHR2 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for AMHR2 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH12J053423 Promoter/Enhancer 1.5 EPDnew Ensembl ENCODE 600.7 +1.2 1228 2.6 RFX1 LEF1 IKZF1 JUND ZIC2 REST HDAC1 ZNF600 FOXJ2 EP300 AMHR2 PRR13 SP1 AAAS piR-56451-033 MN298678-017
GH12J053424 Enhancer 0.5 Ensembl 600.7 -0.2 -154 0.2 ZFHX2 GLIS1 ZNF398 EGR2 ESRRA AMHR2 MN309562 SP1 MN298678-017
GH12J053378 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 12.9 -42.3 -42292 6.9 SP1 CREB1 CTCF ZBTB33 HNRNPL ARID3A ATF7 PRDM10 ZNF629 TFE3 SP1 NONHSAG011234.2 piR-32705 piR-50444-079 AAAS PRR13 HOXC8 HOXC9 ENSG00000258086 AMHR2
GH12J053452 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE CraniofacialAtlas 13.1 +29.2 29246 3.8 ARHGAP35 SP1 CREB1 GATAD2A CTCF ATF7 PRDM10 REST ZNF629 TFE3 PCBP2 AAAS SP1 ZNF740 ENSG00000258344 MYG1 MAP3K12 HNRNPA1 ATF7 PRR13
GH12J053320 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE CraniofacialAtlas 10.9 -100.5 -100454 6.4 SP1 HNRNPL CREB1 GATAD2A CTCF PRDM10 ZNF629 REST TFE3 RFX1 AAAS lnc-SP7-1 piR-45394 piR-40339 ESPL1 ZNF740 HNRNPA1 TARBP2 NPFF MAP3K12
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around AMHR2 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for AMHR2

Top Transcription factor binding sites by QIAGEN in the AMHR2 gene promoter:
  • AREB6
  • GR
  • GR-alpha
  • GR-beta
  • MZF-1
  • NF-E2
  • NF-E2 p45
  • Nkx2-5
  • NRSF form 1
  • NRSF form 2

Genomic Locations for AMHR2 Gene

Genomic Locations for AMHR2 Gene
chr12:53,423,855-53,431,672
(GRCh38/hg38)
Size:
7,818 bases
Orientation:
Plus strand
chr12:53,817,639-53,825,318
(GRCh37/hg19)
Size:
7,680 bases
Orientation:
Plus strand

Genomic View for AMHR2 Gene

Genes around AMHR2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
AMHR2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for AMHR2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for AMHR2 Gene

Proteins for AMHR2 Gene

  • Protein details for AMHR2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q16671-AMHR2_HUMAN
    Recommended name:
    Anti-Muellerian hormone type-2 receptor
    Protein Accession:
    Q16671
    Secondary Accessions:
    • A0AVE1
    • B9EGB7
    • E9PGD2
    • F8W1D2
    • Q13762
    • Q647K2

    Protein attributes for AMHR2 Gene

    Size:
    573 amino acids
    Molecular mass:
    62750 Da
    Cofactor:
    Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
    Cofactor:
    Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for AMHR2 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for AMHR2 Gene

Selected DME Specific Peptides for AMHR2 Gene

Q16671:
  • DFCNANYSHLPP
  • PPPFQLAYEAELG
  • GLRELLEDCWDADPEARLTAECVQQRL

Post-translational modifications for AMHR2 Gene

  • Glycosylation at Asn66 and Asn119
  • Modification sites at PhosphoSitePlus

Domains & Families for AMHR2 Gene

Gene Families for AMHR2 Gene

HGNC:
IUPHAR :
Human Protein Atlas (HPA):
  • Disease related genes
  • Enzymes
  • Potential drug targets
  • Predicted intracellular proteins
  • Predicted membrane proteins

Protein Domains for AMHR2 Gene

InterPro:
Blocks:
  • Domain in TGF-beta receptor/activin receptor, type I/II
ProtoNet:

Suggested Antigen Peptide Sequences for AMHR2 Gene

GenScript: Design optimal peptide antigens:
  • MIS type II receptor (AMHR2_HUMAN)
  • Anti-Mullerian hormone receptor type II (Q647K2_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q16671

UniProtKB/Swiss-Prot:

AMHR2_HUMAN :
  • Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
Family:
  • Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
genes like me logo Genes that share domains with AMHR2: view

Function for AMHR2 Gene

Molecular function for AMHR2 Gene

UniProtKB/Swiss-Prot Function:
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=[receptor-protein]-L-threonine + ATP = [receptor-protein]-O-phospho-L-threonine + ADP + H(+); Xref=Rhea:RHEA:44880, Rhea:RHEA-COMP:11024, Rhea:RHEA-COMP:11025, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013, ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216; EC=2.7.11.30;.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=[receptor-protein]-L-serine + ATP = [receptor-protein]-O-phospho-L-serine + ADP + H(+); Xref=Rhea:RHEA:18673, Rhea:RHEA-COMP:11022, Rhea:RHEA-COMP:11023, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616, ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.30;.
GENATLAS Biochemistry:
anti-Mullerian hormone receptor TGF,beta superfamily

Enzyme Numbers (IUBMB) for AMHR2 Gene

Phenotypes From GWAS Catalog for AMHR2 Gene

Gene Ontology (GO) - Molecular Function for AMHR2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000166 nucleotide binding IEA --
GO:0004672 protein kinase activity IEA --
GO:0004674 protein serine/threonine kinase activity IEA,IBA 21873635
GO:0004675 transmembrane receptor protein serine/threonine kinase activity IEA --
GO:0005024 transforming growth factor beta-activated receptor activity IBA --
genes like me logo Genes that share ontologies with AMHR2: view
genes like me logo Genes that share phenotypes with AMHR2: view

Human Phenotype Ontology for AMHR2 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for AMHR2 Gene

MGI Knock Outs for AMHR2:

Animal Model Products

CRISPR Products

miRNA for AMHR2 Gene

miRTarBase miRNAs that target AMHR2

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for AMHR2

Clone Products

  • Addgene plasmids for AMHR2

No data available for Transcription Factor Targets and HOMER Transcription for AMHR2 Gene

Localization for AMHR2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for AMHR2 Gene

Membrane. Single-pass type I membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for AMHR2 gene
Compartment Confidence
plasma membrane 4
extracellular 3
nucleus 2
cytoskeleton 1
mitochondrion 1
endoplasmic reticulum 1
cytosol 1
golgi apparatus 1
peroxisome 0

Subcellular locations from the

Human Protein Atlas (HPA)
  • Vesicles (3)
  • Centriolar satellite (2)
  • Cytosol (2)
  • Nucleoplasm (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for AMHR2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0005887 integral component of plasma membrane IEA --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
GO:0043235 receptor complex IBA 21873635
genes like me logo Genes that share ontologies with AMHR2: view

Pathways & Interactions for AMHR2 Gene

genes like me logo Genes that share pathways with AMHR2: view

Pathways by source for AMHR2 Gene

1 BioSystems pathway for AMHR2 Gene
1 Cell Signaling Technology pathway for AMHR2 Gene

SIGNOR curated interactions for AMHR2 Gene

Activates:
Is activated by:

Gene Ontology (GO) - Biological Process for AMHR2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001568 blood vessel development IBA --
GO:0001880 Mullerian duct regression NAS 14750901
GO:0001944 vasculature development IBA --
GO:0006468 protein phosphorylation IEA,IBA 21873635
GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway IEA --
genes like me logo Genes that share ontologies with AMHR2: view

Drugs & Compounds for AMHR2 Gene

(5) Drugs for AMHR2 Gene - From: DrugBank, PharmGKB, HMDB, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Metformin Approved Pharma AMP-activated protein kinase (AMPK) activator 2210
Magnesium Approved, Experimental, Investigational Pharma 0
Manganese Approved Nutra 56
ATP Investigational Nutra Agonist, Activator, Partial agonist, Antagonist, Full agonist, Gating inhibitor, Pore Blocker, Potentiation, Target 0

(1) Additional Compounds for AMHR2 Gene - From: HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
ADP
  • 5'-Adenylphosphoric acid
  • Adenosine 5'-diphosphate
  • ADENOSINE-5'-diphosphATE
  • H3ADP
  • 5'-Adenylphosphate
Agonist, Full agonist, Partial agonist, Gating inhibitor, Antagonist 58-64-0
genes like me logo Genes that share compounds with AMHR2: view

Transcripts for AMHR2 Gene

mRNA/cDNA for AMHR2 Gene

3 REFSEQ mRNAs :
8 NCBI additional mRNA sequence :
7 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for AMHR2

Clone Products

  • Addgene plasmids for AMHR2

Alternative Splicing Database (ASD) splice patterns (SP) for AMHR2 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12
SP1: - -
SP2: - -
SP3: -
SP4: -

Relevant External Links for AMHR2 Gene

GeneLoc Exon Structure for
AMHR2

Expression for AMHR2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for AMHR2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for AMHR2 Gene

This gene is overexpressed in Adrenal Gland (x23.6), Ovary (x12.9), and Testis (x5.5).

Protein differential expression in normal tissues from HIPED for AMHR2 Gene

This gene is overexpressed in Stomach (67.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for AMHR2 Gene



Protein tissue co-expression partners for AMHR2 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for AMHR2

SOURCE GeneReport for Unigene cluster for AMHR2 Gene:

Hs.659889

Evidence on tissue expression from TISSUES for AMHR2 Gene

  • Adrenal gland(2.4)

Phenotype-based relationships between genes and organs from Gene ORGANizer for AMHR2 Gene

Germ Layers:
  • ectoderm
  • endoderm
  • mesoderm
Systems:
  • digestive
  • endocrine
  • reproductive
  • skeletal muscle
Regions:
Abdomen:
  • abdominal wall
  • intestine
Pelvis:
  • ovary
  • penis
  • prostate
  • testicle
  • vagina
  • vas deferens
genes like me logo Genes that share expression patterns with AMHR2: view

No data available for mRNA Expression by UniProt/SwissProt for AMHR2 Gene

Orthologs for AMHR2 Gene

This gene was present in the common ancestor of animals.

Orthologs for AMHR2 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia AMHR2 30 31
  • 99.65 (n)
OneToOne
Dog
(Canis familiaris)
Mammalia AMHR2 30 31
  • 88.65 (n)
OneToOne
Cow
(Bos Taurus)
Mammalia AMHR2 30 31
  • 85.88 (n)
OneToOne
Mouse
(Mus musculus)
Mammalia Amhr2 30 17 31
  • 82.26 (n)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Amhr2 30
  • 81.75 (n)
Chicken
(Gallus gallus)
Aves -- 31
  • 22 (a)
ManyToMany
Lizard
(Anolis carolinensis)
Reptilia AMHR2 31
  • 43 (a)
OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia LOC100498418 30
  • 48.94 (n)
Zebrafish
(Danio rerio)
Actinopterygii si:dkey-101k6.5 31
  • 22 (a)
ManyToMany
Fruit Fly
(Drosophila melanogaster)
Insecta wit 31
  • 18 (a)
OneToMany
Sea Squirt
(Ciona savignyi)
Ascidiacea -- 31
  • 24 (a)
ManyToMany
Species where no ortholog for AMHR2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)

Evolution for AMHR2 Gene

ENSEMBL:
Gene Tree for AMHR2 (if available)
TreeFam:
Gene Tree for AMHR2 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for AMHR2: view image

Paralogs for AMHR2 Gene

(1) SIMAP similar genes for AMHR2 Gene using alignment to 2 proteins:

  • AMHR2_HUMAN
  • H3BPI9_HUMAN
genes like me logo Genes that share paralogs with AMHR2: view

Variants for AMHR2 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for AMHR2 Gene

SNP ID Clinical significance and condition Chr 12 pos Variation AA Info Type
689555 Pathogenic: Male pseudohermaphroditism 53,429,479(+) C/T NONSENSE
731907 Likely Benign: not provided 53,424,449(+) C/A SYNONYMOUS_VARIANT
734341 Likely Benign: not provided 53,425,829(+) C/T SYNONYMOUS_VARIANT
798295 Likely Benign: not provided 53,424,713(+) C/T SYNONYMOUS_VARIANT
rs137853104 Pathogenic: Persistent mullerian duct syndrome, type II. Persistent Muellerian duct syndrome 2 (PMDS2) [MIM:261550] 53,429,907(+) G/Ap.Arg406Gln MISSENSE_VARIANT,INTRON_VARIANT

Additional dbSNP identifiers (rs#s) for AMHR2 Gene

Variation tolerance for AMHR2 Gene

Residual Variation Intolerance Score: 17.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.25; 25.02% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for AMHR2 Gene

Human Gene Mutation Database (HGMD)
AMHR2
SNPedia medical, phenotypic, and genealogical associations of SNPs for
AMHR2

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for AMHR2 Gene

Disorders for AMHR2 Gene

MalaCards: The human disease database

(18) MalaCards diseases for AMHR2 Gene - From: UniProtKB/Swiss-Prot, OMIM, ClinVar, GTR, Orphanet, DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
persistent mullerian duct syndrome, types i and ii
  • pmds
persistent mullerian duct syndrome
  • pmds
pseudohermaphroditism
  • indeterminate sex and pseudohermaphroditism
mixed gonadal dysgenesis
  • gonadal dysgenesis mixed
anovulation
- elite association - COSMIC cancer census association via MalaCards
Search AMHR2 in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

AMHR2_HUMAN
  • Persistent Muellerian duct syndrome 2 (PMDS2) [MIM:261550]: A form of male pseudohermaphroditism characterized by a failure of Muellerian duct regression in otherwise normal males. {ECO:0000269 PubMed:11549681, ECO:0000269 PubMed:8872466}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Genatlas disease for AMHR2 Gene

persistent Müllerian duct syndrome

Additional Disease Information for AMHR2

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
genes like me logo Genes that share disorders with AMHR2: view

Publications for AMHR2 Gene

  1. Anti-Müllerian hormone and anti-Müllerian hormone type II receptor polymorphisms are associated with follicular phase estradiol levels in normo-ovulatory women. (PMID: 17337470) Kevenaar ME … Visser JA (Human reproduction (Oxford, England) 2007) 3 23 41
  2. Human ovarian cancer, cell lines, and primary ascites cells express the human Mullerian inhibiting substance (MIS) type II receptor, bind, and are responsive to MIS. (PMID: 10589763) Masiakos PT … Donahoe PK (Clinical cancer research : an official journal of the American Association for Cancer Research 1999) 3 4 23
  3. Insensitivity to anti-müllerian hormone due to a mutation in the human anti-müllerian hormone receptor. (PMID: 7493017) Imbeaud S … Picard JY (Nature genetics 1995) 2 3 4
  4. A large-scale candidate gene association study of age at menarche and age at natural menopause. (PMID: 20734064) He C … Hunter DJ (Human genetics 2010) 3 41
  5. Association study of four key folliculogenesis genes in polycystic ovary syndrome. (PMID: 20236105) Sproul K … Goodarzi MO (BJOG : an international journal of obstetrics and gynaecology 2010) 3 41

Products for AMHR2 Gene

Sources for AMHR2 Gene