Aliases for AMELY Gene
External Ids for AMELY Gene
Previous HGNC Symbols for AMELY Gene
Previous GeneCards Identifiers for AMELY Gene
This gene encodes a member of the amelogenin family of extracellular matrix proteins. Amelogenins are involved in biomineralization during tooth enamel development. Mutations in a related gene on chromosome X cause X-linked amelogenesis imperfecta. [provided by RefSeq, Jul 2008]
GeneCards Summary for AMELY Gene
AMELY (Amelogenin Y-Linked) is a Protein Coding gene. Diseases associated with AMELY include Amelogenesis Imperfecta. Gene Ontology (GO) annotations related to this gene include structural constituent of tooth enamel. An important paralog of this gene is AMELX.
UniProtKB/Swiss-Prot Summary for AMELY Gene
Plays a role in biomineralization. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel.