Aliases for AMDHD2 Gene
External Ids for AMDHD2 Gene
Previous GeneCards Identifiers for AMDHD2 Gene
GeneCards Summary for AMDHD2 Gene
AMDHD2 (Amidohydrolase Domain Containing 2) is a Protein Coding gene. Diseases associated with AMDHD2 include Tick-Borne Relapsing Fever and Eumycotic Mycetoma. Among its related pathways are Transport to the Golgi and subsequent modification and Metabolism of proteins. Gene Ontology (GO) annotations related to this gene include hydrolase activity and N-acetylglucosamine-6-phosphate deacetylase activity. An important paralog of this gene is ENSG00000259784.
UniProtKB/Swiss-Prot Summary for AMDHD2 Gene
Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6-phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway. Although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded.