Aliases for ALX3 Gene
External Ids for ALX3 Gene
Previous HGNC Symbols for ALX3 Gene
Previous GeneCards Identifiers for ALX3 Gene
This gene encodes a nuclear protein with a homeobox DNA-binding domain that functions as a transcriptional regulator involved in cell-type differentiation and development. Preferential methylation of this gene's promoter is associated with advanced-stage neuroblastoma tumors. [provided by RefSeq, Jul 2008]
GeneCards Summary for ALX3 Gene
ALX3 (ALX Homeobox 3) is a Protein Coding gene. Diseases associated with ALX3 include Frontonasal Dysplasia 1 and Cerebral Hemisphere Lipoma. Gene Ontology (GO) annotations related to this gene include sequence-specific DNA binding. An important paralog of this gene is ALX4.
UniProtKB/Swiss-Prot Summary for ALX3 Gene
Transcriptional regulator with a possible role in patterning of mesoderm during development.