External Ids for ALS2CL Gene
Previous GeneCards Identifiers for ALS2CL Gene
GeneCards Summary for ALS2CL Gene
ALS2CL (ALS2 C-Terminal Like) is a Protein Coding gene. Diseases associated with ALS2CL include Deafness, Autosomal Recessive 6. Among its related pathways are RAB GEFs exchange GTP for GDP on RABs and Vesicle-mediated transport. Gene Ontology (GO) annotations related to this gene include identical protein binding and Rab GTPase binding. An important paralog of this gene is RSPH10B.
UniProtKB/Swiss-Prot Summary for ALS2CL Gene
Acts as a guanine nucleotide exchange factor (GEF) for Rab5 GTPase. Regulates the ALS2-mediated endosome dynamics.