This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cyt... See more...

Aliases for ALOX5AP Gene

Aliases for ALOX5AP Gene

  • Arachidonate 5-Lipoxygenase Activating Protein 2 3 5
  • Arachidonate 5-Lipoxygenase-Activating Protein 2 3 4
  • MK-886-Binding Protein 2 3 4
  • FLAP 2 3 4
  • Five-Lipoxygenase Activating Protein 2
  • ALOX5AP 5

External Ids for ALOX5AP Gene

Previous GeneCards Identifiers for ALOX5AP Gene

  • GC13P029289
  • GC13P025289
  • GC13P030239
  • GC13P029108
  • GC13P029109
  • GC13P030207
  • GC13P031309
  • GC13P012127

Summaries for ALOX5AP Gene

Entrez Gene Summary for ALOX5AP Gene

  • This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2011]

GeneCards Summary for ALOX5AP Gene

ALOX5AP (Arachidonate 5-Lipoxygenase Activating Protein) is a Protein Coding gene. Diseases associated with ALOX5AP include Stroke, Ischemic and Myocardial Infarction. Among its related pathways are Folate Metabolism and Eicosanoid Synthesis. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and enzyme binding. An important paralog of this gene is LTC4S.

UniProtKB/Swiss-Prot Summary for ALOX5AP Gene

  • Required for leukotriene biosynthesis by ALOX5 (5-lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes.

Tocris Summary for ALOX5AP Gene

  • Lipoxygenases (LOXs) are a family of non-heme iron dioxygenases that are involved in the production and metabolism of fatty acid hydroperoxidases. There are six lipoxygenase isozymes; 5-LOX, 12R-LOX, 12S-LOX, 15-LOX-1, 15-LOX-2 and E-LOX.

Gene Wiki entry for ALOX5AP Gene

No data available for CIViC Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ALOX5AP Gene

Genomics for ALOX5AP Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for ALOX5AP Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH13J030734 Promoter/Enhancer 1.9 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 625.6 +22.9 22863 4.5 POLR2A BACH1 STAT3 RELA TCF12 IKZF2 RCOR1 TRIM22 EED ARID3A ALOX5AP USPL1 HSALNG0096135 lnc-USPL1-2 MEDAG
GH13J030712 Promoter/Enhancer 1 Ensembl ENCODE 600.7 -0.2 -161 0.2 ETV6 PKNOX1 CEBPB NR3C1 ZSCAN29 FOS GABPA NR2F2 EP300 CTCF ALOX5AP lnc-USPL1-2 piR-32214-134 USPL1
GH13J030714 Enhancer 0.4 FANTOM5 649.1 +1.5 1509 0.6 SPI1 ALOX5AP lnc-USPL1-2 USPL1 HMGB1 HSALNG0096135 MEDAG
GH13J030739 Promoter/Enhancer 1.5 FANTOM5 Ensembl ENCODE dbSUPER 50.3 +26.9 26917 1.7 ZNF629 JUND TRIM22 SOX6 PKNOX1 SCRT2 EED CEBPB ARID3A DPF2 HSALNG0096135 ALOX5AP USPL1 lnc-USPL1-2 MEDAG
GH13J030742 Promoter/Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 38.9 +31.8 31843 6 SP1 CREB1 BACH1 JUND ZNF143 RELA TCF12 IKZF2 TRIM22 GABPA ALOX5AP HMGB1 USPL1 HSALNG0096135 LINC00398 MEDAG
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ALOX5AP on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ALOX5AP

Top Transcription factor binding sites by QIAGEN in the ALOX5AP gene promoter:
  • AML1a
  • AP-1
  • GATA-3
  • GR
  • GR-alpha
  • Nkx2-5
  • POU3F2
  • POU3F2 (N-Oct-5a)
  • POU3F2 (N-Oct-5b)
  • STAT1

Genomic Locations for ALOX5AP Gene

Genomic Locations for ALOX5AP Gene
chr13:30,713,478-30,764,428
(GRCh38/hg38)
Size:
50,951 bases
Orientation:
Plus strand
chr13:31,287,615-31,338,565
(GRCh37/hg19)
Size:
50,951 bases
Orientation:
Plus strand

Genomic View for ALOX5AP Gene

Genes around ALOX5AP on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ALOX5AP Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ALOX5AP Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ALOX5AP Gene

Proteins for ALOX5AP Gene

  • Protein details for ALOX5AP Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P20292-AL5AP_HUMAN
    Recommended name:
    Arachidonate 5-lipoxygenase-activating protein
    Protein Accession:
    P20292
    Secondary Accessions:
    • Q5VV04

    Protein attributes for ALOX5AP Gene

    Size:
    161 amino acids
    Molecular mass:
    18157 Da
    Quaternary structure:
    • Homotrimer. Interacts with LTC4S and ALOX5.

    Three dimensional structures from OCA and Proteopedia for ALOX5AP Gene

neXtProt entry for ALOX5AP Gene

Post-translational modifications for ALOX5AP Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ALOX5AP Gene

Protein Products

  • Signalway Proteins for ALOX5AP
  • Abcam proteins for ALOX5AP

No data available for DME Specific Peptides for ALOX5AP Gene

Domains & Families for ALOX5AP Gene

Gene Families for ALOX5AP Gene

Human Protein Atlas (HPA):
  • Disease related genes
  • Predicted membrane proteins

Protein Domains for ALOX5AP Gene

InterPro:
Blocks:
  • Membrane-associated proteins in eicosanoid and glutathione metabolism (MAPEG)
  • Five-lipoxygenase activating protein signature
ProtoNet:

Suggested Antigen Peptide Sequences for ALOX5AP Gene

GenScript: Design optimal peptide antigens:
  • MK-886-binding protein (AL5AP_HUMAN)

Graphical View of Domain Structure for InterPro Entry

P20292

UniProtKB/Swiss-Prot:

AL5AP_HUMAN :
  • The C-terminal part after residue 140 is mostly unstructured.
  • Belongs to the MAPEG family.
Domain:
  • The C-terminal part after residue 140 is mostly unstructured.
Family:
  • Belongs to the MAPEG family.
genes like me logo Genes that share domains with ALOX5AP: view

Function for ALOX5AP Gene

Molecular function for ALOX5AP Gene

UniProtKB/Swiss-Prot Function:
Required for leukotriene biosynthesis by ALOX5 (5-lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes.
GENATLAS Biochemistry:
arachidonate 5-lipoxygenase activating protein,expressed in cells of myeloid origin,localized in the nuclear envelop,involved in the biosynthesis of leukotrienes (role in inflammation),microsomal,GST superfamily

Phenotypes From GWAS Catalog for ALOX5AP Gene

Gene Ontology (GO) - Molecular Function for ALOX5AP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004051 arachidonate 5-lipoxygenase activity IEA --
GO:0004364 glutathione transferase activity IBA 21873635
GO:0004464 leukotriene-C4 synthase activity IBA 21873635
GO:0004602 glutathione peroxidase activity IBA 21873635
GO:0005515 protein binding IPI 19233132
genes like me logo Genes that share ontologies with ALOX5AP: view
genes like me logo Genes that share phenotypes with ALOX5AP: view

Human Phenotype Ontology for ALOX5AP Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for ALOX5AP Gene

MGI Knock Outs for ALOX5AP:

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ALOX5AP

No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for ALOX5AP Gene

Localization for ALOX5AP Gene

Subcellular locations from UniProtKB/Swiss-Prot for ALOX5AP Gene

Nucleus membrane. Multi-pass membrane protein. Endoplasmic reticulum membrane. Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ALOX5AP gene
Compartment Confidence
nucleus 5
endoplasmic reticulum 5
plasma membrane 3
extracellular 2
cytosol 2
lysosome 2
cytoskeleton 1
mitochondrion 1
peroxisome 1
golgi apparatus 1

Gene Ontology (GO) - Cellular Components for ALOX5AP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0005635 nuclear envelope IEA,TAS --
GO:0005783 endoplasmic reticulum IEA,IDA 19233132
GO:0005789 endoplasmic reticulum membrane IEA --
GO:0005829 cytosol IEA --
genes like me logo Genes that share ontologies with ALOX5AP: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for ALOX5AP Gene

Pathways & Interactions for ALOX5AP Gene

genes like me logo Genes that share pathways with ALOX5AP: view

Pathways by source for ALOX5AP Gene

Gene Ontology (GO) - Biological Process for ALOX5AP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0002540 leukotriene production involved in inflammatory response IEA --
GO:0002675 positive regulation of acute inflammatory response IEA --
GO:0006691 leukotriene metabolic process IEA,TAS --
GO:0019370 leukotriene biosynthetic process IEA,IDA 2300173
GO:0019372 lipoxygenase pathway IEA,TAS --
genes like me logo Genes that share ontologies with ALOX5AP: view

No data available for SIGNOR curated interactions for ALOX5AP Gene

Drugs & Compounds for ALOX5AP Gene

(30) Drugs for ALOX5AP Gene - From: DrugBank, ApexBio, DGIdb, Tocris, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Zileuton Approved, Investigational, Withdrawn Pharma Inhibitor, Inhibition 5-lipoxygenase (5-LOX) inhibitor, orally active 20
DG031 Investigational Pharma Target, inhibitor 0
AM103 Investigational Pharma Target 0
Fiboflapon Investigational Pharma Target 0
MK 886 Pharma Inhibitor of 5-lipoxygenase-activating protein (FLAP) 0

(14) Additional Compounds for ALOX5AP Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs

(5) Tocris Compounds for ALOX5AP Gene

Compound Action Cas Number
2-TEDC 5-, 12-, 15-Lipoxygenase inhibitor 132465-10-2
Baicalein 5- and 12-Lipoxygenase inhibitor 491-67-8
BAY-X 1005 Orally active 5-lipoxygenase activating protein (FLAP) inhibitor 128253-31-6
BW-B 70C 5-Lipoxygenase inhibitor 134470-38-5
MK 886 Inhibitor of 5-lipoxygenase-activating protein (FLAP) 118414-82-7

(5) ApexBio Compounds for ALOX5AP Gene

Compound Action Cas Number
AM679 FLAP inhibitor 1206880-66-1
GSK2190915 sodium salt 1196070-26-4
Malotilate Tyrosine kinase inhibitors 59937-28-9
MK-0591 FLAP inhibitor,potent and selective 136668-42-3
Zileuton 5-lipoxygenase (5-LOX) inhibitor, orally active 111406-87-2
genes like me logo Genes that share compounds with ALOX5AP: view

Drug Products

Transcripts for ALOX5AP Gene

mRNA/cDNA for ALOX5AP Gene

2 REFSEQ mRNAs :
4 NCBI additional mRNA sequence :
3 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ALOX5AP

Alternative Splicing Database (ASD) splice patterns (SP) for ALOX5AP Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5 ^ 6a · 6b
SP1: - - -
SP2: -
SP3: - - - - -
SP4: -

Relevant External Links for ALOX5AP Gene

GeneLoc Exon Structure for
ALOX5AP

Expression for ALOX5AP Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ALOX5AP Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for ALOX5AP Gene

This gene is overexpressed in Whole Blood (x40.3).

Protein differential expression in normal tissues from HIPED for ALOX5AP Gene

This gene is overexpressed in Nasal epithelium (37.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for ALOX5AP Gene



Protein tissue co-expression partners for ALOX5AP Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ALOX5AP

SOURCE GeneReport for Unigene cluster for ALOX5AP Gene:

Hs.507658

Evidence on tissue expression from TISSUES for ALOX5AP Gene

  • Blood(3.4)
  • Spleen(3)
  • Bone marrow(2.9)
  • Lung(2.9)
  • Intestine(2.8)
  • Nervous system(2.6)
  • Heart(2.6)
  • Lymph node(2.6)
  • Muscle(2.2)
  • Skin(2.1)
  • Liver(2.1)
  • Adrenal gland(2.1)
genes like me logo Genes that share expression patterns with ALOX5AP: view

No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ALOX5AP Gene

Orthologs for ALOX5AP Gene

This gene was present in the common ancestor of chordates.

Orthologs for ALOX5AP Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia ALOX5AP 30 31
  • 98.62 (n)
OneToOne
Oppossum
(Monodelphis domestica)
Mammalia ALOX5AP 31
  • 91 (a)
OneToOne
Platypus
(Ornithorhynchus anatinus)
Mammalia ALOX5AP 31
  • 90 (a)
OneToOne
Dog
(Canis familiaris)
Mammalia ALOX5AP 30 31
  • 86.89 (n)
OneToOne
Cow
(Bos Taurus)
Mammalia ALOX5AP 30 31
  • 86.13 (n)
OneToOne
Mouse
(Mus musculus)
Mammalia Alox5ap 30 17 31
  • 85.71 (n)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Alox5ap 30
  • 85.09 (n)
Chicken
(Gallus gallus)
Aves ALOX5AP 30 31
  • 76.19 (n)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia ALOX5AP 31
  • 72 (a)
OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia alox5ap 30
  • 72.05 (n)
Str.11819 30
Zebrafish
(Danio rerio)
Actinopterygii alox5ap 30 31
  • 62.82 (n)
OneToOne
wufj65d02 30
Species where no ortholog for ALOX5AP was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)

Evolution for ALOX5AP Gene

ENSEMBL:
Gene Tree for ALOX5AP (if available)
TreeFam:
Gene Tree for ALOX5AP (if available)
Aminode:
Evolutionary constrained regions (ECRs) for ALOX5AP: view image

Paralogs for ALOX5AP Gene

Paralogs for ALOX5AP Gene

(2) SIMAP similar genes for ALOX5AP Gene using alignment to 1 proteins:

  • AL5AP_HUMAN
genes like me logo Genes that share paralogs with ALOX5AP: view

Variants for ALOX5AP Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ALOX5AP Gene

SNP ID Clinical significance and condition Chr 13 pos Variation AA Info Type
764166 Likely Benign: not provided 30,744,085(+) C/T SYNONYMOUS_VARIANT
773270 Benign: not provided 30,744,112(+) C/T SYNONYMOUS_VARIANT
rs281864911 Not Provided: not provided 30,758,476(+) T/C INTRON_VARIANT

Additional dbSNP identifiers (rs#s) for ALOX5AP Gene

Structural Variations from Database of Genomic Variants (DGV) for ALOX5AP Gene

Variant ID Type Subtype PubMed ID
esv2747225 CNV deletion 23290073
esv3406702 CNV duplication 20981092
nsv1145656 CNV deletion 24896259
nsv474284 CNV novel sequence insertion 20440878
nsv561396 CNV loss 21841781
nsv561397 CNV loss 21841781
nsv832574 CNV gain 17160897
nsv984 CNV insertion 18451855

Variation tolerance for ALOX5AP Gene

Residual Variation Intolerance Score: 47.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.47; 10.28% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ALOX5AP Gene

Human Gene Mutation Database (HGMD)
ALOX5AP
SNPedia medical, phenotypic, and genealogical associations of SNPs for
ALOX5AP

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ALOX5AP Gene

Disorders for ALOX5AP Gene

MalaCards: The human disease database

(6) MalaCards diseases for ALOX5AP Gene - From: OMIM, GTR, DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
stroke, ischemic
  • cerebrovascular accident
myocardial infarction
  • myocardial infarction, susceptibility to
asthma
  • asthma, susceptibility to
macular holes
  • macular hole
cerebrovascular disease
  • cerebrovascular accident
- elite association - COSMIC cancer census association via MalaCards

UniProtKB/Swiss-Prot

AL5AP_HUMAN
  • Ischemic stroke (ISCHSTR) [MIM:601367]: A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. Ischemic strokes, resulting from vascular occlusion, is considered to be a highly complex disease consisting of a group of heterogeneous disorders with multiple genetic and environmental risk factors. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry.
  • Note=Genetic variations in ALOX5AP may be associated with susceptibility to myocardial infarction. Involvement in myocardial infarction is however unclear: according to some authors (PubMed:14770184), a 4-SNP haplotype in ALOX5AP confers risk of myocardial infarction, while according to other (PubMed:17304054) ALOX5AP is not implicated in this condition. {ECO:0000269 PubMed:14770184, ECO:0000269 PubMed:17304054}.

Additional Disease Information for ALOX5AP

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
genes like me logo Genes that share disorders with ALOX5AP: view

No data available for Genatlas for ALOX5AP Gene

Publications for ALOX5AP Gene

  1. The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke. (PMID: 14770184) Helgadottir A … Stefansson K (Nature genetics 2004) 3 4 23 41
  2. Gene characterization and promoter analysis of the human 5-lipoxygenase-activating protein (FLAP). (PMID: 1673682) Kennedy BP … Dixon RA (The Journal of biological chemistry 1991) 2 3 4 23
  3. Association of a genetic variant in the ALOX5AP with higher risk of ischemic stroke: a case-control, meta-analysis and functional study. (PMID: 20357438) Domingues-Montanari S … Montaner J (Cerebrovascular diseases (Basel, Switzerland) 2010) 3 23 41
  4. [Association of the ALOX5AP gene SG13S114 A/T polymorphism with atherosclerosis]. (PMID: 20376802) He YL … Chen QY (Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics 2010) 3 23 41
  5. The role of LTA4H and ALOX5AP genes in the risk for asthma in Latinos. (PMID: 20067482) Via M … Genetics of Asthma in Latino Americans (GALA) Study (Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2010) 3 23 41

Products for ALOX5AP Gene

  • Signalway Proteins for ALOX5AP

Sources for ALOX5AP Gene