Aliases for ALOX12P2 Gene

Aliases for ALOX12P2 Gene

  • Arachidonate 12-Lipoxygenase Pseudogene 2 2 3 5
  • Hair And Skin Epidermal-Type 12-Lipoxygenase-Related Pseudogene 3
  • 12-Lipoxygenase-Related Protein 3
  • ALOX12E 3

External Ids for ALOX12P2 Gene

Previous GeneCards Identifiers for ALOX12P2 Gene

  • GC17P007185
  • GC17P007528
  • GC17P006701
  • GC17U900075
  • GC17P006997
  • GC17P006737
  • GC17P006759

Summaries for ALOX12P2 Gene

GeneCards Summary for ALOX12P2 Gene

ALOX12P2 (Arachidonate 12-Lipoxygenase Pseudogene 2) is a Pseudogene.

Additional gene information for ALOX12P2 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ALOX12P2 Gene

Genomics for ALOX12P2 Gene

GeneHancer (GH) Regulatory Elements for ALOX12P2 Gene

Promoters and enhancers for ALOX12P2 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17J006853 Promoter/Enhancer 1.5 Ensembl ENCODE CraniofacialAtlas 507 +0.9 886 2.3 ZBTB40 CTCF POLR2G ZFX ZIC2 POLR2A TGIF2 TEAD1 ZKSCAN8 GABPA ALOX12P2 TEKT1 FBXO39 SLC13A5 lnc-TEKT1-3 lnc-ALOX12-1
GH17J006867 Enhancer 1.1 FANTOM5 Ensembl ENCODE 5.6 +15.6 15590 3.7 TCF12 ZNF10 EP300 CTBP1 WT1 BRCA1 FOS FOSL2 CEBPB CHD2 piR-48759-116 TEKT1 ALOX12P2 FBXO39 lnc-TEKT1-3 lnc-ALOX12-1
GH17J006843 Enhancer 0.7 Ensembl ENCODE 5.7 -10.0 -9975 0.8 CTCF RFX1 REST RAD21 SMC3 ZNF654 ZNF24 TRIM22 ZNF143 lnc-ALOX12-1 ALOX12 ALOX12-AS1 RNASEK RNASEK-C17orf49 SLC13A5 C17orf100 MED31 XAF1 SLC16A11
GH17J006893 Promoter 0.5 Ensembl 5.4 +40.1 40125 0.2 EZH2 ZFHX2 SLC13A5 ALOX12P2 lnc-ALOX12-2 piR-48209-267 lnc-ALOX12-1 ALOX12-AS1
GH17J006876 Enhancer 0.3 Ensembl 5.7 +21.9 21925 0.6 STAT1 TEKT1 MIR195 SLC13A5 ALOX12P2 piR-48209-267 piR-48759-116 lnc-ALOX12-1 ALOX12-AS1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ALOX12P2 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ALOX12P2 gene promoter:
  • C/EBPalpha
  • E2F
  • E2F-1
  • LCR-F1
  • Lmo2
  • Olf-1
  • p53
  • XBP-1
  • ZID

Genomic Locations for ALOX12P2 Gene

Genomic Locations for ALOX12P2 Gene
chr17:6,853,576-6,954,107
(GRCh38/hg38)
Size:
100,532 bases
Orientation:
Plus strand
chr17:6,757,180-6,857,426
(GRCh37/hg19)
Size:
100,247 bases
Orientation:
Plus strand

Genomic View for ALOX12P2 Gene

Genes around ALOX12P2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ALOX12P2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ALOX12P2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ALOX12P2 Gene

Proteins for ALOX12P2 Gene

Post-translational modifications for ALOX12P2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for ALOX12P2 Gene

Domains & Families for ALOX12P2 Gene

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for ALOX12P2 Gene

Function for ALOX12P2 Gene

Molecular function for ALOX12P2 Gene

GENATLAS Biochemistry:
arachidonate-12-lipoxygenase,epidermal type,expressed pseudogene

Phenotypes From GWAS Catalog for ALOX12P2 Gene

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ALOX12P2 Gene

Localization for ALOX12P2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for ALOX12P2 Gene

Pathways & Interactions for ALOX12P2 Gene

PathCards logo

SuperPathways for ALOX12P2 Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for ALOX12P2 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for ALOX12P2 Gene

Drugs & Compounds for ALOX12P2 Gene

No Compound Related Data Available

Transcripts for ALOX12P2 Gene

mRNA/cDNA for ALOX12P2 Gene

5 NCBI additional mRNA sequence :
12 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for ALOX12P2 Gene

No ASD Table

Relevant External Links for ALOX12P2 Gene

GeneLoc Exon Structure for
ALOX12P2

Expression for ALOX12P2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ALOX12P2 Gene

mRNA differential expression in normal tissues according to GTEx for ALOX12P2 Gene

This gene is overexpressed in Pituitary (x8.3) and Liver (x8.1).

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ALOX12P2

SOURCE GeneReport for Unigene cluster for ALOX12P2 Gene:

Hs.378695
genes like me logo Genes that share expression patterns with ALOX12P2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ALOX12P2 Gene

Orthologs for ALOX12P2 Gene

Evolution for ALOX12P2 Gene

ENSEMBL:
Gene Tree for ALOX12P2 (if available)
TreeFam:
Gene Tree for ALOX12P2 (if available)

No data available for Orthologs for ALOX12P2 Gene

Paralogs for ALOX12P2 Gene

No data available for Paralogs for ALOX12P2 Gene

Variants for ALOX12P2 Gene

Structural Variations from Database of Genomic Variants (DGV) for ALOX12P2 Gene

Variant ID Type Subtype PubMed ID
dgv3095n100 CNV loss 25217958
dgv5440n54 CNV loss 21841781
esv21524 CNV loss 19812545
esv2422288 CNV deletion 17116639
esv2715590 CNV deletion 23290073
esv2761944 CNV loss 21179565
esv3582504 CNV loss 25503493
nsv1059072 CNV loss 25217958
nsv1060335 CNV loss 25217958
nsv518777 CNV gain 19592680
nsv521515 CNV loss 19592680

Additional Variant Information for ALOX12P2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ALOX12P2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Additional dbSNP identifiers (rs#s) and Variation tolerance for ALOX12P2 Gene

Disorders for ALOX12P2 Gene

Additional Disease Information for ALOX12P2

No disorders were found for ALOX12P2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ALOX12P2 Gene

Publications for ALOX12P2 Gene

  1. Cloning of a human "epidermal-type" 12-lipoxygenase-related gene and chromosomal localization to 17p13. (PMID: 9691181) Sun D … Funk CD (Cytogenetics and cell genetics 1998) 2 3 54
  2. Genome-wide association study of bipolar disorder accounting for effect of body mass index identifies a new risk allele in TCF7L2. (PMID: 24322204) Winham SJ … Biernacka JM (Molecular psychiatry 2014) 3 54
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 54
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 54
  5. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo MF … Soares MB (Genome research 1996) 3 54

Products for ALOX12P2 Gene

Sources for ALOX12P2 Gene