Aliases for ALDH3B1 Gene
Aliases for ALDH3B1 Gene
External Ids for ALDH3B1 Gene
- HGNC: 410
- Entrez Gene: 221
- Ensembl: ENSG00000006534
- OMIM: 600466
- UniProtKB: P43353
Previous HGNC Symbols for ALDH3B1 Gene
- ALDH7
Previous GeneCards Identifiers for ALDH3B1 Gene
- GC11P070300
- GC11P069474
- GC11P067553
- GC11P067534
- GC11P067776
- GC11P064111
Summaries for ALDH3B1 Gene
-
This gene encodes a member of the aldehyde dehydrogenase protein family. Aldehyde dehydrogenases are a family of isozymes that may play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The encoded protein is able to oxidize long-chain fatty aldehydes in vitro, and may play a role in protection from oxidative stress. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
GeneCards Summary for ALDH3B1 Gene
ALDH3B1 (Aldehyde Dehydrogenase 3 Family Member B1) is a Protein Coding gene. Among its related pathways are Phenylalanine metabolism and Innate Immune System. Gene Ontology (GO) annotations related to this gene include oxidoreductase activity and 3-chloroallyl aldehyde dehydrogenase activity. An important paralog of this gene is ALDH3B2.
UniProtKB/Swiss-Prot for ALDH3B1 Gene
-
Oxidizes medium and long chain saturated and unsaturated aldehydes. Metabolizes also benzaldehyde. Low activity towards acetaldehyde and 3,4-dihydroxyphenylacetaldehyde. May not metabolize short chain aldehydes. May use both NADP(+) and NAD(+) as cofactors. May have a protective role against the cytotoxicity induced by lipid peroxidation.
Additional gene information for ALDH3B1 Gene
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ALDH3B1 Gene
Genomics for ALDH3B1 Gene
GeneHancer (GH) Regulatory Elements for ALDH3B1 Gene
Promoters and enhancers for ALDH3B1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around ALDH3B1 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for ALDH3B1 Gene
Genomic Locations for ALDH3B1 Gene
- chr11:68,008,547-68,029,282
- (GRCh38/hg38)
- Size:
- 20,736 bases
- Orientation:
- Plus strand
- chr11:67,776,048-67,796,744
- (GRCh37/hg19)
Genomic View for ALDH3B1 Gene
Genes around ALDH3B1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 11q13.2 by Ensembl
- 11q13.2 by Entrez Gene
- 11q13.2 by HGNC
ALDH3B1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ALDH3B1 Gene
Proteins for ALDH3B1 Gene
-
Protein details for ALDH3B1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P43353-AL3B1_HUMAN
- Recommended name:
- Aldehyde dehydrogenase family 3 member B1
- Protein Accession:
- P43353
- A3FMP9
- Q53XL5
- Q8N515
- Q96CK8
Protein attributes for ALDH3B1 Gene
- Size:
- 468 amino acids
- Molecular mass:
- 51840 Da
- Quaternary structure:
- No Data Available
Protein Expression for ALDH3B1 Gene
Selected DME Specific Peptides for ALDH3B1 Gene
- P43353:
-
- NAGQTCV
- VTLELGG
- VVLKPSE
- TLELGGKNPCYVDDNCDPQ
- TLELGGK
- IAPWNYP
- GQTCVAPDY
- SGMGRYHGKF
- EKPLALY
Post-translational modifications for ALDH3B1 Gene
- Dually lipidated in the C-terminus; prenylation occurs prior to, and is a prerequisite for palmitoylation. It is also required for activity towards long-chain substrates.
- Ubiquitination at Lys41, Lys89, posLast=375375, and Lys437
- Modification sites at PhosphoSitePlus
Other Protein References for ALDH3B1 Gene
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for ALDH3B1
- Novus Biologicals Antibodies for ALDH3B1
- Invitrogen Antibodies for ALDH3B1
- Search GeneTex for Antibodies for ALDH3B1
Protein Products
-
OriGene Purified Proteins for ALDH3B1
- Search Origene for MassSpec and Protein Over-expression Lysates for ALDH3B1
- Origene Custom Protein Services for ALDH3B1
- Search GeneTex for Proteins for ALDH3B1
-
Abcam proteins for ALDH3B1
Assay Products
Domains & Families for ALDH3B1 Gene
Gene Families for ALDH3B1 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Enzymes
- Predicted intracellular proteins
Protein Domains for ALDH3B1 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for ALDH3B1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P43353- Family:
-
- Belongs to the aldehyde dehydrogenase family.
Function for ALDH3B1 Gene
Molecular function for ALDH3B1 Gene
- UniProtKB/Swiss-Prot CatalyticActivity:
- An aldehyde + NAD(P)(+) + H(2)O = a carboxylate + NAD(P)H.
- UniProtKB/Swiss-Prot Function:
- Oxidizes medium and long chain saturated and unsaturated aldehydes. Metabolizes also benzaldehyde. Low activity towards acetaldehyde and 3,4-dihydroxyphenylacetaldehyde. May not metabolize short chain aldehydes. May use both NADP(+) and NAD(+) as cofactors. May have a protective role against the cytotoxicity induced by lipid peroxidation.
Enzyme Numbers (IUBMB) for ALDH3B1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004028 | 3-chloroallyl aldehyde dehydrogenase activity | TAS | 7828891 |
| GO:0004029 | aldehyde dehydrogenase (NAD) activity | IEA | -- |
| GO:0004030 | aldehyde dehydrogenase [NAD(P)+] activity | IDA,TAS | -- |
| GO:0005515 | protein binding | IPI | 25416956 |
| GO:0016491 | oxidoreductase activity | IEA | -- |
Phenotypes for ALDH3B1 Gene
- MGI mutant phenotypes for ALDH3B1:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for ALDH3B1:
-
- Increased vaccinia virus (VACV) infection
- Dynamic nuclei (hole, folded or small irregular)
- Negative genetic interaction between PTEN-/- and PTEN+/+
- Increased shRNA abundance (Z-score > 2)
- Decreased shRNA abundance (Z-score < -2)
- Increased HPV16-GFP infection
- Weakly decreased NFAT1-GFP nuclear translocation
- Negative genetic interaction between BLM-/- and BLM+/+
- Upregulation of Wnt/beta-catenin pathway after WNT3A stimulation
Animal Models for ALDH3B1 Gene
- MGI Knock Outs for ALDH3B1:
-
- Aldh3b1 tm1b(EUCOMM)Wtsi
Animal Model Products
-
Taconic Biosciences Mouse Models for ALDH3B1
- Cyagen custom Knockout/knockin (KOKI) mouse models for ALDH3B1
-
-
ViGene Biosciences lentiviral particle packaged cDNA for ALDH3B1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ALDH3B1 gene
- Search ViGene Biosciences for ALDH3B1
CRISPR Products
-
OriGene CRISPR knockouts for ALDH3B1
- genomics-online: gRNA clones - Search results for 142 available ALDH3B1 gene related products
- Overview of 142 available ALDH3B1 gene related products
- Applied Biological Materials CRISPR for ALDH3B1
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for ALDH3B1
- GenScript: Design CRISPR guide RNA sequences for ALDH3B1
miRNA for ALDH3B1 Gene
- miRTarBase miRNAs that target ALDH3B1
-
- hsa-mir-2110 (MIRT451820)
- hsa-mir-6780b-5p (MIRT451821)
- hsa-mir-4725-3p (MIRT451822)
- hsa-mir-4271 (MIRT451823)
- hsa-mir-1255b-5p (MIRT451824)
- hsa-mir-1255a (MIRT451825)
- hsa-mir-6894-5p (MIRT451826)
- hsa-mir-6077 (MIRT451827)
- hsa-mir-107 (MIRT451828)
- hsa-mir-103a-3p (MIRT451829)
- hsa-mir-3605-5p (MIRT451830)
- hsa-mir-4468 (MIRT451831)
- hsa-mir-6840-3p (MIRT451832)
- hsa-mir-6838-5p (MIRT451833)
- hsa-mir-497-5p (MIRT451834)
- hsa-mir-424-5p (MIRT451835)
- hsa-mir-195-5p (MIRT451836)
- hsa-mir-16-5p (MIRT451837)
- hsa-mir-15b-5p (MIRT451838)
- hsa-mir-15a-5p (MIRT451839)
miRNA Products
- Search ViGene Biosciences for ALDH3B1
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ALDH3B1
- Browse OriGene Inhibitory RNA Products For ALDH3B1
- genomics-online: shRNA clones - Search results for 142 available ALDH3B1 gene related products
- Overview of 142 available ALDH3B1 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for ALDH3B1 gene
Clone Products
-
OriGene ORF clones in human for ALDH3B1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for ALDH3B1
- VectorBuilder custom plasmid, inducible vectors for ALDH3B1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ALDH3B1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for ALDH3B1
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for ALDH3B1
-
ViGene Biosciences adenoviral particle packaged cDNA for ALDH3B1 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for ALDH3B1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ALDH3B1 gene
No data available for Phenotypes From GWAS Catalog , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for ALDH3B1 Gene
Localization for ALDH3B1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ALDH3B1 Gene
- Cell membrane; Lipid-anchor. Note=Primarily in the plasma membrane as well as in some punctate structures in the cytoplasm.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005737 | cytoplasm | IDA | 20699116 |
| GO:0005829 | cytosol | IEA | -- |
| GO:0005886 | plasma membrane | TAS | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0030667 | secretory granule membrane | TAS | -- |
No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for ALDH3B1 Gene
Pathways & Interactions for ALDH3B1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Drug metabolism - cytochrome P450 | ||
| 2 | Metabolism |
.37
|
|
| 3 | Innate Immune System |
.61
|
|
| 4 | Phenylalanine metabolism | ||
| 5 | Sphingolipid metabolism | ||
Pathways by source for ALDH3B1 Gene
2 BioSystems pathways for ALDH3B1 Gene
7 Reactome pathways for ALDH3B1 Gene
9 KEGG pathways for ALDH3B1 Gene
UniProtKB/Swiss-Prot P43353-AL3B1_HUMAN
- Pathway: Alcohol metabolism; ethanol degradation; acetate from ethanol: step 2/2.
Interacting Proteins for ALDH3B1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006066 | alcohol metabolic process | TAS | 7828891 |
| GO:0006068 | ethanol catabolic process | IEA | -- |
| GO:0006081 | cellular aldehyde metabolic process | IEA | -- |
| GO:0006629 | lipid metabolic process | TAS | 7828891 |
| GO:0008152 | metabolic process | IEA | -- |
No data available for SIGNOR curated interactions for ALDH3B1 Gene
Drugs & Compounds for ALDH3B1 Gene
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| 3,4-Dihydroxymandelaldehyde |
|
13023-73-9 |
|
|||
| 3,4-Dihydroxymandelic acid |
|
775-01-9 |
|
|||
| 3,4-Dihydroxyphenylacetaldehyde |
|
5707-55-1 |
|
|||
| 3-Aminopropionaldehyde |
|
352-92-1 |
|
|||
| 3-Carbamoyl-2-phenylpropionaldehyde |
|
|
Transcripts for ALDH3B1 Gene
mRNA/cDNA for ALDH3B1 Gene
- (5) REFSEQ mRNAs :
- (9) Additional mRNA sequences :
- (168) Selected AceView cDNA sequences:
- (10) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for ALDH3B1 Gene
- Aldehyde dehydrogenase 3 family, member B1:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for ALDH3B1
- genomics-online: gRNA clones - Search results for 142 available ALDH3B1 gene related products
- Overview of 142 available ALDH3B1 gene related products
- Applied Biological Materials CRISPR for ALDH3B1
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for ALDH3B1
- GenScript: Design CRISPR guide RNA sequences for ALDH3B1
miRNA Products
- Search ViGene Biosciences for ALDH3B1
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ALDH3B1
- Browse OriGene Inhibitory RNA Products For ALDH3B1
- genomics-online: shRNA clones - Search results for 142 available ALDH3B1 gene related products
- Overview of 142 available ALDH3B1 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for ALDH3B1 gene
Clone Products
-
OriGene ORF clones in human for ALDH3B1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for ALDH3B1
- VectorBuilder custom plasmid, inducible vectors for ALDH3B1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ALDH3B1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for ALDH3B1
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | ^ | 10a | · | 10b | ^ | 11 | ^ | 12 | ^ | 13a | · | 13b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | |||||||||||||||||||||||||||||
| SP2: | - | ||||||||||||||||||||||||||||||||
| SP3: | - | - | |||||||||||||||||||||||||||||||
| SP4: | |||||||||||||||||||||||||||||||||
| SP5: | - | - | - | ||||||||||||||||||||||||||||||
| SP6: |
Expression for ALDH3B1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Brain (Nervous System)
- Myelinating Oligodendrocyte Cells Forebrain White Matter
-
Glial Cells
- Myelinating Oligodendrocyte Cells Forebrain White Matter
-
Eye (Sensory Organs)
- Mature Retinal Pigmented Epithelium Cells Retinal Pigmented Epithelium
-
Epithelial Cells
- Mature Retinal Pigmented Epithelium Cells Retinal Pigmented Epithelium
- Lung (Respiratory System)
- Ovary (Reproductive System)
mRNA differential expression in normal tissues according to GTEx for ALDH3B1 Gene
This gene is overexpressed in Whole Blood (x9.2) and Lung (x4.2).
This gene is overexpressed in Nasal epithelium (60.6).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for ALDH3B1 Gene
NURSA nuclear receptor signaling pathways regulating expression of ALDH3B1 Gene:
ALDH3B1SOURCE GeneReport for Unigene cluster for ALDH3B1 Gene:
Hs.523841mRNA Expression by UniProt/SwissProt for ALDH3B1 Gene:
P43353-AL3B1_HUMAN
Tissue specificity:
Highest expression in kidney and lung.
Primer Products
-
OriGene qPCR primer pairs and template standards for ALDH3B1
-
OriGene qPCR primer pairs for ALDH3B1
- genomics-online: primer clones - Search results for 142 available ALDH3B1 gene related products
- Overview of 142 available ALDH3B1 gene related products
Gene Expression Assay Products
No data available for Protein tissue co-expression partners , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ALDH3B1 Gene
Orthologs for ALDH3B1 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| dog (Canis familiaris) |
Mammalia | ALDH3B1 33 34 |
|
||
| cow (Bos Taurus) |
Mammalia | ALDH3B1 33 34 |
|
||
| chimpanzee (Pan troglodytes) |
Mammalia | ALDH3B1 33 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Aldh3b1 33 |
|
||
| mouse (Mus musculus) |
Mammalia | Aldh3b1 33 16 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | -- 34 |
|
OneToMany | |
| chicken (Gallus gallus) |
Aves | ALDH3B1 33 |
|
||
| -- 34 |
|
ManyToMany | |||
| -- 34 |
|
ManyToMany | |||
| lizard (Anolis carolinensis) |
Reptilia | -- 34 |
|
ManyToMany | |
| -- 34 |
|
ManyToMany | |||
| tropical clawed frog (Silurana tropicalis) |
Amphibia | aldh3b1 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | aldh3b1 33 34 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | Aldh-III 35 33 34 |
|
||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP005124 33 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | alh-5 34 |
|
ManyToMany | |
| alh-4 34 |
|
ManyToMany | |||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | HFD1 33 34 |
|
||
| K. lactis yeast (Kluyveromyces lactis) |
Saccharomycetes | KLLA0B12540g 33 |
|
||
| Alicante grape (Vitis vinifera) |
eudicotyledons | Vvi.7577 33 |
|
||
| rice (Oryza sativa) |
Liliopsida | Os.18249 33 |
|
||
| wheat (Triticum aestivum) |
Liliopsida | Ta.1546 33 |
|
||
| bread mold (Neurospora crassa) |
Ascomycetes | NCU04013 33 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.6683 34 |
|
ManyToMany | |
| CSA.9635 34 |
|
ManyToMany |
- Species where no ortholog for ALDH3B1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
Paralogs for ALDH3B1 Gene
(4) SIMAP similar genes for ALDH3B1 Gene using alignment to 4 proteins:
Variants for ALDH3B1 Gene
| SNP ID | Clin | Chr 11 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000024444 | -- | 68,026,585(+) | C/T | intron_variant | |
| rs1000242508 | -- | 68,028,733(+) | G/T | 3_prime_UTR_variant | |
| rs1000334507 | -- | 68,014,878(+) | C/A | intron_variant | |
| rs1000442220 | -- | 68,009,469(+) | A/G | genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant | |
| rs1000474865 | -- | 68,009,745(+) | C/T | genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv1221n100 | CNV | gain | 25217958 |
| dgv156n27 | CNV | loss | 19166990 |
| dgv1981n54 | CNV | gain | 21841781 |
| dgv1983n54 | CNV | loss | 21841781 |
| esv2759835 | CNV | gain+loss | 17122850 |
| nsv1038960 | CNV | loss | 25217958 |
| nsv428260 | CNV | gain | 18775914 |
| nsv468606 | CNV | gain | 19166990 |
| nsv468615 | CNV | loss | 19166990 |
| nsv469856 | CNV | gain | 16826518 |
| nsv469964 | CNV | loss | 18288195 |
| nsv475863 | CNV | novel sequence insertion | 20440878 |
| nsv555277 | CNV | loss | 21841781 |
| nsv555278 | CNV | loss | 21841781 |
| nsv825963 | CNV | gain | 20364138 |
| nsv8836 | CNV | gain | 18304495 |
| nsv951026 | CNV | deletion | 24416366 |
| nsv983037 | CNV | duplication | 23825009 |
Gene Damage Index Score:
2.86;
48.23% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for ALDH3B1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- ALDH3B1
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ALDH3B1 Gene
Disorders for ALDH3B1 Gene
Additional Disease Information for ALDH3B1
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No disorders were found for ALDH3B1 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ALDH3B1 Gene
Publications for ALDH3B1 Gene
- Cloning of a cDNA encoding human ALDH7, a new member of the aldehyde dehydrogenase family. (PMID: 7828891) Hsu LC … Yoshida A (Gene 1994) 2 3 4 22 58
- Evidence of epistasis between the catechol-O-methyltransferase and aldehyde dehydrogenase 3B1 genes in paranoid schizophrenia. (PMID: 19159868) Wang Y … Shen Y (Biological psychiatry 2009) 3 22 44 58
- Substrate specificity, plasma membrane localization, and lipid modification of the aldehyde dehydrogenase ALDH3B1. (PMID: 23721920) Kitamura T … Kihara A (Biochimica et biophysica acta 2013) 3 4 58
- Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects. (PMID: 19343046) Saito A … Kamatani N (Journal of human genetics 2009) 3 44 58
- Expression and initial characterization of human ALDH3B1. (PMID: 17382292) Marchitti SA … Vasiliou V (Biochemical and biophysical research communications 2007) 3 4 58
Products for ALDH3B1 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Human Proteins and Enzymes
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody ServicesOriGene Antibodies for ALDH3B1
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for ALDH3B1
- Search Origene for MassSpec and Protein Over-expression Lysates for ALDH3B1
- Origene Custom Protein Services for ALDH3B1
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ALDH3B1
- Browse OriGene Inhibitory RNA Products For ALDH3B1
- OriGene qPCR primer pairs and template standards for ALDH3B1
- OriGene qPCR primer pairs for ALDH3B1
- OriGene CRISPR knockouts for ALDH3B1
- OriGene ORF clones in human for ALDH3B1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For ALDH3B1
- GenScript: Next-day shipping of latest version cDNA ORF clones for ALDH3B1 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for ALDH3B1
- GenScript Custom Assay Services for ALDH3B1
- GenScript Custom overexpressing Cell Line Services for ALDH3B1
- GenScript: Design CRISPR guide RNA sequences for ALDH3B1
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for ALDH3B1
- Sino Biological Human cDNA Clone for ALDH3B1
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse Sino Biological ELISA Kits
- Browse Sino Biological ELISA Pair Sets
- Browse Sino Biological CRO Services
- Browse Sino Biological Control Vectors
- Sino Biological Transfection Reagent
- Sino Biological Anti-His Tag Antibody
- Novus Biologicals Antibodies for ALDH3B1
- Novus Biologicals lysates and proteins for ALDH3B1
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam proteins for ALDH3B1
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Browse Antibodies at Cloud-Clone Corp.
- Browse Proteins at Cloud-Clone Corp.
- Browse Assay Kits at Cloud-Clone Corp.
- Browse Knockouts at Cloud-Clone Corp.
- Browse Knockins at Cloud-Clone Corp.
- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Taconic Biosciences Mouse Models for ALDH3B1
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- Invitrogen Antibodies for ALDH3B1
- Cyagen custom Knockout/knockin (KOKI) mouse models for ALDH3B1
- VectorBuilder custom plasmid, inducible vectors for ALDH3B1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ALDH3B1
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 66 available ALDH3B1 Antibodies ranked by validation data
- Compare Top ALDH3B1 Antibodies
- antibodies-online: Search results for 5 available ALDH3B1 Elisa Kits ranked by validation data
- Compare Top ALDH3B1 Elisa Kits
- antibodies-online: Search results for 6 available ALDH3B1 Proteins ranked by validation data
- Compare Top ALDH3B1 Proteins
- Search GeneTex for Antibodies for ALDH3B1
- Search GeneTex for Proteins for ALDH3B1
- ViGene Biosciences adenoviral particle packaged cDNA for ALDH3B1 gene
- ViGene Biosciences lentiviral particle packaged cDNA for ALDH3B1 gene
- ViGene Biosciences ready-to-package AAV shRNAs for ALDH3B1 gene
- Search ViGene Biosciences for ALDH3B1
- Horizon Cell Lines for ALDH3B1
- genomics-online: cdna clones - Search results for 142 available ALDH3B1 gene related products
- Overview of 142 available ALDH3B1 gene related products
- orf clones - Search results for 142 available ALDH3B1 gene related products
- Overview of 142 available ALDH3B1 gene related products
- genomics-online: gRNA clones - Search results for 142 available ALDH3B1 gene related products
- Overview of 142 available ALDH3B1 gene related products
- genomics-online: primer clones - Search results for 142 available ALDH3B1 gene related products
- Overview of 142 available ALDH3B1 gene related products
- genomics-online: shRNA clones - Search results for 142 available ALDH3B1 gene related products
- Overview of 142 available ALDH3B1 gene related products
Sources for ALDH3B1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems