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Aliases for ALDH3A1 Gene

Aliases for ALDH3A1 Gene

  • Aldehyde Dehydrogenase 3 Family Member A1 2 3 5
  • Aldehyde Dehydrogenase, Dimeric NADP-Preferring 2 3
  • EC 1.2.1.5 4 56
  • ALDHIII 3 4
  • ALDH3 3 4
  • Aldehyde Dehydrogenase 3 Family, Member A1 2
  • Aldehyde Dehydrogenase Family 3 Member A1 4
  • Aldehyde Dehydrogenase Isozyme 3 3
  • Aldehyde Dehydrogenase Type III 3
  • Stomach Aldehyde Dehydrogenase 3
  • Aldehyde Dehydrogenase 3 4
  • EC 1.2.1 56

External Ids for ALDH3A1 Gene

Previous HGNC Symbols for ALDH3A1 Gene

  • ALDH3

Previous GeneCards Identifiers for ALDH3A1 Gene

  • GC17M019747
  • GC17M021277
  • GC17M019545
  • GC17M019803
  • GC17M019581
  • GC17M019641
  • GC17M019020

Summaries for ALDH3A1 Gene

Entrez Gene Summary for ALDH3A1 Gene

  • Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008]

GeneCards Summary for ALDH3A1 Gene

ALDH3A1 (Aldehyde Dehydrogenase 3 Family Member A1) is a Protein Coding gene. Diseases associated with ALDH3A1 include Breast Adenocarcinoma. Among its related pathways are Phenylalanine metabolism and Metabolism. Gene Ontology (GO) annotations related to this gene include oxidoreductase activity and aldehyde dehydrogenase (NAD) activity. An important paralog of this gene is ALDH3A2.

UniProtKB/Swiss-Prot for ALDH3A1 Gene

  • ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde (Probable). They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation (Probable). Oxidizes medium and long chain aldehydes into non-toxic fatty acids (PubMed:1737758). Preferentially oxidizes aromatic aldehyde substrates (PubMed:1737758). Comprises about 50 percent of corneal epithelial soluble proteins (By similarity). May play a role in preventing corneal damage caused by ultraviolet light (By similarity).

Gene Wiki entry for ALDH3A1 Gene

Additional gene information for ALDH3A1 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ALDH3A1 Gene

Genomics for ALDH3A1 Gene

GeneHancer (GH) Regulatory Elements for ALDH3A1 Gene

Promoters and enhancers for ALDH3A1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17I019744 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE dbSUPER 550.8 +3.4 3427 2 HDGF CTCF KLF1 ZNF449 ZSCAN4 MAX ZNF2 RAD21 ZNF335 ZFHX2 ALDH3A1 SLC47A2 NOS2P3 ENSG00000264785
GH17I019747 Promoter/Enhancer 1.7 EPDnew Ensembl ENCODE dbSUPER 556.7 +0.5 511 1.2 SOX13 FOXA2 CHD4 SIN3A ZNF48 POLR2A RERE FOSL2 NR2F6 CREM ALDH3A1 ENSG00000264785
GH17I019718 Enhancer 1.3 Ensembl ENCODE dbSUPER 17.5 +29.0 29019 3.7 ELF3 FOXA2 MLX ARID4B THRB ZNF48 RAD21 RARA ZNF143 FOS SLC47A2 ENSG00000262681 ALDH3A1 SNORA59B SLC47A1 ENSG00000252349 ENSG00000261033 ENSG00000264785
GH17I019726 Enhancer 1.5 FANTOM5 Ensembl ENCODE dbSUPER 6.1 +21.1 21123 3.1 FOXA2 NFIB RAD21 YY1 ZNF335 ZNF23 RCOR1 ATF7 EGR2 ZNF362 UPF3AP2 ENSG00000252349 ALDH3A2 SLC47A1 PRPSAP2 B9D1 SLC47A2 ALDH3A1 MAPK7 ENSG00000262681
GH17I019733 Enhancer 0.8 ENCODE 7.2 +14.7 14651 1.3 FOXA2 RAD21 THRB ZSCAN9 RARA CREM MIXL1 HMG20B SP5 PPARG ENSG00000252349 SLC47A2 ALDH3A1 SLC47A1 ENSG00000264785 ENSG00000262681
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ALDH3A1 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ALDH3A1 gene promoter:

Genomic Locations for ALDH3A1 Gene

Genomic Locations for ALDH3A1 Gene
chr17:19,737,984-19,748,943
(GRCh38/hg38)
Size:
10,960 bases
Orientation:
Minus strand
chr17:19,641,297-19,652,256
(GRCh37/hg19)

Genomic View for ALDH3A1 Gene

Genes around ALDH3A1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ALDH3A1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ALDH3A1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ALDH3A1 Gene

Proteins for ALDH3A1 Gene

  • Protein details for ALDH3A1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P30838-AL3A1_HUMAN
    Recommended name:
    Aldehyde dehydrogenase, dimeric NADP-preferring
    Protein Accession:
    P30838
    Secondary Accessions:
    • A8K828
    • Q9BT37

    Protein attributes for ALDH3A1 Gene

    Size:
    453 amino acids
    Molecular mass:
    50395 Da
    Quaternary structure:
    • Homodimer.

    Three dimensional structures from OCA and Proteopedia for ALDH3A1 Gene

neXtProt entry for ALDH3A1 Gene

Selected DME Specific Peptides for ALDH3A1 Gene

P30838:
  • VTLELGG
  • AGNAVVLKP
  • APDYILC
  • VVLKPSE
  • TLELGGK
  • ACRRIAWGKFMNSGQTCVAPDYILCDPSIQ
  • GQTCVAPDY
  • EKPLALY
  • CVRSLEEAIQFI
  • SGMGSYHG

Post-translational modifications for ALDH3A1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Antibody Products

  • R&D Systems Antibodies for ALDH3A1 (Aldehyde Dehydrogenase 3-A1/ALDH3A1)
  • Abcam antibodies for ALDH3A1

Domains & Families for ALDH3A1 Gene

Gene Families for ALDH3A1 Gene

HGNC:
Human Protein Atlas (HPA):
  • Enzymes
  • Predicted intracellular proteins

Graphical View of Domain Structure for InterPro Entry

P30838

UniProtKB/Swiss-Prot:

AL3A1_HUMAN :
  • Belongs to the aldehyde dehydrogenase family.
Family:
  • Belongs to the aldehyde dehydrogenase family.
genes like me logo Genes that share domains with ALDH3A1: view

Function for ALDH3A1 Gene

Molecular function for ALDH3A1 Gene

UniProtKB/Swiss-Prot BiophysicochemicalProperties:
Kinetic parameters: Note=Has a high Km for acetaldehyde.;
UniProtKB/Swiss-Prot CatalyticActivity:
An aldehyde + NAD(P)(+) + H(2)O = a carboxylate + NAD(P)H.
UniProtKB/Swiss-Prot Function:
ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde (Probable). They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation (Probable). Oxidizes medium and long chain aldehydes into non-toxic fatty acids (PubMed:1737758). Preferentially oxidizes aromatic aldehyde substrates (PubMed:1737758). Comprises about 50 percent of corneal epithelial soluble proteins (By similarity). May play a role in preventing corneal damage caused by ultraviolet light (By similarity).

Enzyme Numbers (IUBMB) for ALDH3A1 Gene

Phenotypes From GWAS Catalog for ALDH3A1 Gene

Gene Ontology (GO) - Molecular Function for ALDH3A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004028 3-chloroallyl aldehyde dehydrogenase activity IEA --
GO:0004029 aldehyde dehydrogenase (NAD) activity IDA 1737758
GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity TAS --
GO:0005515 protein binding IPI 21044950
GO:0008106 alcohol dehydrogenase (NADP+) activity IDA 1737758
genes like me logo Genes that share ontologies with ALDH3A1: view
genes like me logo Genes that share phenotypes with ALDH3A1: view

Animal Models for ALDH3A1 Gene

MGI Knock Outs for ALDH3A1:

Animal Model Products

miRNA for ALDH3A1 Gene

miRTarBase miRNAs that target ALDH3A1

Clone Products

No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for ALDH3A1 Gene

Localization for ALDH3A1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ALDH3A1 Gene

Cytoplasm.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ALDH3A1 gene
Compartment Confidence
plasma membrane 5
extracellular 5
cytosol 5
endoplasmic reticulum 4
nucleus 3
mitochondrion 2
peroxisome 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (4)
  • Plasma membrane (2)
  • Vesicles (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for ALDH3A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space HDA,IDA 22664934
GO:0005737 cytoplasm IEA --
GO:0005783 endoplasmic reticulum IDA --
GO:0005829 cytosol TAS --
GO:0005886 plasma membrane IDA --
genes like me logo Genes that share ontologies with ALDH3A1: view

Pathways & Interactions for ALDH3A1 Gene

genes like me logo Genes that share pathways with ALDH3A1: view

Gene Ontology (GO) - Biological Process for ALDH3A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006081 cellular aldehyde metabolic process IDA 1737758
GO:0006805 xenobiotic metabolic process TAS --
GO:0008152 metabolic process IEA --
GO:0055114 oxidation-reduction process IDA 1737758
genes like me logo Genes that share ontologies with ALDH3A1: view

No data available for SIGNOR curated interactions for ALDH3A1 Gene

Drugs & Compounds for ALDH3A1 Gene

(21) Drugs for ALDH3A1 Gene - From: DrugBank, HMDB, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
NADH Approved Nutra Target 0
Chloral hydrate Approved, Illicit, Investigational, Vet_approved Pharma 17
Phenylacetic acid Approved Pharma 12
Trichloroacetate Approved Pharma 0
Water Approved Pharma 0

(35) Additional Compounds for ALDH3A1 Gene - From: Novoseek and HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
Aldophosphamide
Carboxyphosphamide
nadph
  • 2'-(Dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) Adenosine 5'-ester with 1,4-dihydro-1-b-D-ribofuranosylnicotinamide
  • 2'-(Dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) Adenosine 5'-ester with 1,4-dihydro-1-beta-delta-ribofuranosylnicotinamide
  • Adenosine 5'-(trihydrogen diphosphate) 2'-(dihydrogen phosphate) P'-5'-ester with 1,4-dihydro-1-beta-D-ribofuranosyl-3-pyridinecarboxamide
  • Adenosine 5'-(trihydrogen diphosphate) 2'-(dihydrogen phosphate) P'-5'-ester with 1,4-dihydro-1-beta-delta-ribofuranosyl-3-pyridinecarboxamide
  • b-NADPH
53-57-6
3,4-Dihydroxymandelaldehyde
  • 3,4-Dihydroxyphenylglycolaldehyde
  • 3,4-Dihydroxyphenylglycolic aldehyde
  • a,3,4-Trihydroxy-Benzeneacetaldehyde
  • alpha,3,4-Trihydroxy-Benzeneacetaldehyde
13023-73-9
3,4-Dihydroxymandelic acid
  • 3,4 Dihydroxymandelate
  • 3,4 Dihydroxymandelic acid
  • 3,4-Dihydroxymandelate
  • 3,4-Dihydroxyphenylglycolate
  • 3,4-Dihydroxyphenylglycolic acid
775-01-9
genes like me logo Genes that share compounds with ALDH3A1: view

Transcripts for ALDH3A1 Gene

Unigene Clusters for ALDH3A1 Gene

Aldehyde dehydrogenase 3 family, member A1:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ALDH3A1 Gene

ExUns: 1 ^ 2a · 2b · 2c ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6a · 6b · 6c · 6d ^ 7 ^ 8a · 8b · 8c · 8d · 8e ^ 9a · 9b ^ 10 ^ 11a · 11b · 11c · 11d ^
SP1: - - - - - - - - - -
SP2: - - - - - - - - - -
SP3: - - - - - - - - - -
SP4: - - - - - - - - - - - -
SP5: - - - - - - - - - -
SP6: - -
SP7: - -
SP8: - - - - - -
SP9: - - - - - - - - -
SP10: - - - -
SP11: - - - - -
SP12: - -
SP13:
SP14: - - - - - - - - - - -
SP15: - - - - - - -
SP16: - - - - - - - -
SP17: - - -
SP18: - - -
SP19:
SP20: - -

ExUns: 12a · 12b · 12c ^ 13a · 13b · 13c ^ 14a · 14b ^ 15 ^ 16 ^ 17a · 17b
SP1: - - -
SP2: - - - -
SP3: - - - - - -
SP4: - - -
SP5: - - -
SP6: - - -
SP7: -
SP8:
SP9:
SP10:
SP11:
SP12: -
SP13: -
SP14:
SP15:
SP16:
SP17:
SP18:
SP19:
SP20:

Relevant External Links for ALDH3A1 Gene

GeneLoc Exon Structure for
ALDH3A1
ECgene alternative splicing isoforms for
ALDH3A1

Expression for ALDH3A1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ALDH3A1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for ALDH3A1 Gene

This gene is overexpressed in Esophagus - Mucosa (x28.6), Stomach (x10.1), and Minor Salivary Gland (x4.2).

Protein differential expression in normal tissues from HIPED for ALDH3A1 Gene

This gene is overexpressed in Nasal epithelium (33.5), Tonsil (14.7), and Oral epithelium (6.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ALDH3A1 Gene



NURSA nuclear receptor signaling pathways regulating expression of ALDH3A1 Gene:

ALDH3A1

SOURCE GeneReport for Unigene cluster for ALDH3A1 Gene:

Hs.531682

mRNA Expression by UniProt/SwissProt for ALDH3A1 Gene:

P30838-AL3A1_HUMAN
Tissue specificity: High levels in stomach, esophagus and lung; low level in the liver and kidney.

Evidence on tissue expression from TISSUES for ALDH3A1 Gene

  • Pancreas(4.8)
  • Stomach(4.8)
  • Eye(4.6)
  • Lung(4.6)
  • Liver(2)
  • Skin(2)
genes like me logo Genes that share expression patterns with ALDH3A1: view

No data available for Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for ALDH3A1 Gene

Orthologs for ALDH3A1 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for ALDH3A1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ALDH3A1 34 33
  • 99.12 (n)
OneToOne
dog
(Canis familiaris)
Mammalia ALDH3A1 34 33
  • 88.3 (n)
OneToOne
cow
(Bos Taurus)
Mammalia ALDH3A1 34 33
  • 86.53 (n)
OneToOne
rat
(Rattus norvegicus)
Mammalia Aldh3a1 33
  • 82.12 (n)
mouse
(Mus musculus)
Mammalia Aldh3a1 16 34 33
  • 81.24 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia ALDH3A1 34
  • 79 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 34
  • 78 (a)
OneToMany
-- 34
  • 75 (a)
OneToMany
chicken
(Gallus gallus)
Aves ALDH3A2 34
  • 61 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 34
  • 56 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii aldh3a2b 34
  • 54 (a)
ManyToMany
aldh3a2a 34
  • 53 (a)
ManyToMany
aldh3a1 34
  • 49 (a)
ManyToMany
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.864 33
fruit fly
(Drosophila melanogaster)
Insecta Aldh-III 35 34
  • 50 (a)
worm
(Caenorhabditis elegans)
Secernentea alh-5 34
  • 49 (a)
ManyToMany
alh-4 34
  • 46 (a)
ManyToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes HFD1 34 36
  • 30 (a)
OneToMany
thale cress
(Arabidopsis thaliana)
eudicotyledons ALDH3H1 33
  • 48.75 (n)
rice
(Oryza sativa)
Liliopsida Os11g0186200 33
  • 51.4 (n)
Os.5577 33
barley
(Hordeum vulgare)
Liliopsida Hv.4281 33
sea squirt
(Ciona savignyi)
Ascidiacea CSA.6683 34
  • 43 (a)
ManyToMany
CSA.9635 34
  • 40 (a)
ManyToMany
Species where no ortholog for ALDH3A1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for ALDH3A1 Gene

ENSEMBL:
Gene Tree for ALDH3A1 (if available)
TreeFam:
Gene Tree for ALDH3A1 (if available)

Paralogs for ALDH3A1 Gene

Paralogs for ALDH3A1 Gene

genes like me logo Genes that share paralogs with ALDH3A1: view

Variants for ALDH3A1 Gene

Sequence variations from dbSNP and Humsavar for ALDH3A1 Gene

SNP ID Clin Chr 17 pos Variation AA Info Type
rs1000049285 -- 19,749,241(-) T/C upstream_transcript_variant
rs1000222912 -- 19,744,520(-) C/T genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant
rs1000557126 -- 19,750,189(-) G/A upstream_transcript_variant
rs1000858181 -- 19,745,177(-) G/A/C 5_prime_UTR_variant, genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant
rs1001077516 -- 19,750,384(-) C/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for ALDH3A1 Gene

Variant ID Type Subtype PubMed ID
nsv1061317 CNV gain 25217958
nsv1063892 CNV gain 25217958
nsv457704 CNV loss 19166990
nsv470582 CNV loss 18288195
nsv526290 CNV loss 19592680
nsv574580 CNV loss 21841781
nsv953846 CNV deletion 24416366

Variation tolerance for ALDH3A1 Gene

Residual Variation Intolerance Score: 95.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 10.44; 90.95% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ALDH3A1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ALDH3A1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ALDH3A1 Gene

Disorders for ALDH3A1 Gene

MalaCards: The human disease database

(1) MalaCards diseases for ALDH3A1 Gene - From: DISEASES and GeneCards

Disorder Aliases PubMed IDs
breast adenocarcinoma
  • adenocarcinoma of breast
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for ALDH3A1

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with ALDH3A1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for ALDH3A1 Gene

Publications for ALDH3A1 Gene

  1. Human stomach aldehyde dehydrogenase cDNA and genomic cloning, primary structure, and expression in Escherichia coli. (PMID: 1737758) Hsu LC … Yoshida A (The Journal of biological chemistry 1992) 2 3 4 22 58
  2. Influence of polymorphisms of drug metabolizing enzymes (CYP2B6, CYP2C9, CYP2C19, CYP3A4, CYP3A5, GSTA1, GSTP1, ALDH1A1 and ALDH3A1) on the pharmacokinetics of cyclophosphamide and 4-hydroxycyclophosphamide. (PMID: 18496131) Ekhart C … Huitema AD (Pharmacogenetics and genomics 2008) 3 22 44 58
  3. Relations between polymorphisms in drug-metabolising enzymes and toxicity of chemotherapy with cyclophosphamide, thiotepa and carboplatin. (PMID: 18854779) Ekhart C … Huitema AD (Pharmacogenetics and genomics 2008) 3 22 44 58
  4. Mutations associated with Sjögren-Larsson syndrome. (PMID: 9250352) Tsukamoto N … Yoshida A (Annals of human genetics 1997) 3 4 22 58
  5. Human stomach aldehyde dehydrogenase, ALDH3. (PMID: 8493892) Hsu LC … Yoshida A (Advances in experimental medicine and biology 1993) 3 4 22 58

Products for ALDH3A1 Gene

Sources for ALDH3A1 Gene

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