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Aliases for ALDH1L1-AS2 Gene

Subcategory (RNA class) for ALDH1L1-AS2 Gene

non-coding RNA

Quality Score for this RNA gene is

13

Aliases for ALDH1L1-AS2 Gene

  • ALDH1L1 Antisense RNA 2 2 3 5
  • ALDH1L1 Antisense RNA 2 (Non-Protein Coding) 2 3

External Ids for ALDH1L1-AS2 Gene

Previous GeneCards Identifiers for ALDH1L1-AS2 Gene

  • GC00U933052
  • GC03P125898

Summaries for ALDH1L1-AS2 Gene

GeneCards Summary for ALDH1L1-AS2 Gene

ALDH1L1-AS2 (ALDH1L1 Antisense RNA 2) is an RNA Gene, and is affiliated with the non-coding RNA class.

Additional gene information for ALDH1L1-AS2 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ALDH1L1-AS2 Gene

Genomics for ALDH1L1-AS2 Gene

GeneHancer (GH) Regulatory Elements for ALDH1L1-AS2 Gene

Promoters and enhancers for ALDH1L1-AS2 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH03J126178 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 655.2 +0.2 167 3.6 FOXA2 MLX ZFP64 ARID4B DMAP1 ZNF48 YY1 GLIS2 SP3 RXRA ALDH1L1-AS2 ALDH1L1 KLF15 GC03P126153
GH03J126266 Enhancer 1.3 Ensembl ENCODE dbSUPER 7 +87.8 87848 3.4 ATF1 ARID4B SIN3A DMAP1 ZNF48 ETS1 YY1 FOS ATF7 RXRA ENSG00000250934 KLF15 CCDC37-DT CFAP100 ALDH1L1 ALDH1L1-AS2 ENPP7P4 ENSG00000251448 GC03P126153
GH03J126207 Enhancer 1.1 Ensembl ENCODE 6.8 +28.5 28535 1.9 ZNF2 YY1 FOS RXRA YY2 SMARCB1 ZNF518A MAFF ZNF610 GLIS1 KLF15 ALDH1L1-AS2 ALDH1L1 PIR51646 GC03P126153
GH03J126198 Enhancer 0.8 ENCODE 6.1 +18.4 18426 0.4 CTCF IRF2 ATF1 ARID4B BACH1 CEBPG ZNF644 RAD21 YY1 ZNF614 ALDH1L1 ALDH1L1-AS2 GC03P126153 PIR51646
GH03J126184 Enhancer 0.8 ENCODE 5.3 +4.8 4757 1.5 FOXA2 RARA YY1 CREM RXRA REST NR2F2 NFIL3 SP1 MAFF ALDH1L1 ALDH1L1-AS2 GC03P126153
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ALDH1L1-AS2 on UCSC Golden Path with GeneCards custom track

Genomic Locations for ALDH1L1-AS2 Gene

Genomic Locations for ALDH1L1-AS2 Gene
chr3:126,180,065-126,210,169
(GRCh38/hg38)
Size:
30,105 bases
Orientation:
Plus strand
chr3:125,898,908-125,929,012
(GRCh37/hg19)
Size:
30,105 bases
Orientation:
Plus strand

Genomic View for ALDH1L1-AS2 Gene

Genes around ALDH1L1-AS2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ALDH1L1-AS2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ALDH1L1-AS2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ALDH1L1-AS2 Gene

Proteins for ALDH1L1-AS2 Gene

Post-translational modifications for ALDH1L1-AS2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for ALDH1L1-AS2 Gene

Domains & Families for ALDH1L1-AS2 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for ALDH1L1-AS2 Gene

Function for ALDH1L1-AS2 Gene

Phenotypes From GWAS Catalog for ALDH1L1-AS2 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ALDH1L1-AS2 Gene

Localization for ALDH1L1-AS2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for ALDH1L1-AS2 Gene

Pathways & Interactions for ALDH1L1-AS2 Gene

SuperPathways for ALDH1L1-AS2 Gene

No Data Available

Interacting Proteins for ALDH1L1-AS2 Gene

Gene Ontology (GO) - Biological Process for ALDH1L1-AS2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ALDH1L1-AS2 Gene

Drugs & Compounds for ALDH1L1-AS2 Gene

No Compound Related Data Available

Transcripts for ALDH1L1-AS2 Gene

mRNA/cDNA for ALDH1L1-AS2 Gene

(3) Additional mRNA sequences :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :
(4) RNA Central transcripts :

Unigene Clusters for ALDH1L1-AS2 Gene

ALDH1L1 antisense RNA 2:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ALDH1L1-AS2 Gene

No ASD Table

Relevant External Links for ALDH1L1-AS2 Gene

GeneLoc Exon Structure for
ALDH1L1-AS2
ECgene alternative splicing isoforms for
ALDH1L1-AS2

Expression for ALDH1L1-AS2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ALDH1L1-AS2 Gene

mRNA differential expression in normal tissues according to GTEx for ALDH1L1-AS2 Gene

This gene is overexpressed in Heart - Left Ventricle (x4.5).

SOURCE GeneReport for Unigene cluster for ALDH1L1-AS2 Gene:

Hs.633362
genes like me logo Genes that share expression patterns with ALDH1L1-AS2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ALDH1L1-AS2 Gene

Orthologs for ALDH1L1-AS2 Gene

Evolution for ALDH1L1-AS2 Gene

ENSEMBL:
Gene Tree for ALDH1L1-AS2 (if available)
TreeFam:
Gene Tree for ALDH1L1-AS2 (if available)

No data available for Orthologs for ALDH1L1-AS2 Gene

Paralogs for ALDH1L1-AS2 Gene

No data available for Paralogs for ALDH1L1-AS2 Gene

Variants for ALDH1L1-AS2 Gene

Sequence variations from dbSNP and Humsavar for ALDH1L1-AS2 Gene

SNP ID Clin Chr 03 pos Variation AA Info Type
rs1000041908 -- 126,190,739(+) G/A intron_variant
rs1000050284 -- 126,196,892(+) G/A intron_variant
rs1000085984 -- 126,201,509(+) TAACTACAAAAG/ intron_variant
rs1000132385 -- 126,190,149(+) C/G intron_variant
rs1000136323 -- 126,191,092(+) A/G intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ALDH1L1-AS2 Gene

Variant ID Type Subtype PubMed ID
dgv8545n54 CNV loss 21841781
esv3305167 CNV mobile element insertion 20981092
esv3308825 CNV mobile element insertion 20981092
esv3405792 CNV insertion 20981092
esv3442040 CNV insertion 20981092
esv3597677 CNV loss 21293372
nsv1007256 CNV gain 25217958
nsv3985 CNV deletion 18451855

Additional Variant Information for ALDH1L1-AS2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ALDH1L1-AS2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for ALDH1L1-AS2 Gene

Disorders for ALDH1L1-AS2 Gene

Additional Disease Information for ALDH1L1-AS2

No disorders were found for ALDH1L1-AS2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ALDH1L1-AS2 Gene

Publications for ALDH1L1-AS2 Gene

  1. Genome-wide meta-analysis of homocysteine and methionine metabolism identifies five one carbon metabolism loci and a novel association of ALDH1L1 with ischemic stroke. (PMID: 24651765) Williams SR … Framingham Heart Study (PLoS genetics 2014) 3 58
  2. Genetic variants associated with glycine metabolism and their role in insulin sensitivity and type 2 diabetes. (PMID: 23378610) Xie W … Walker M (Diabetes 2013) 3 58
  3. Genome wide association study (GWAS) of Chagas cardiomyopathy in Trypanosoma cruzi seropositive subjects. (PMID: 24324551) Deng X … REDSII Chagas Study Group from the NHLBI Retrovirus Epidemiology Donor Study-II Component International (PloS one 2013) 3 58
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 58
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 58

Products for ALDH1L1-AS2 Gene

Sources for ALDH1L1-AS2 Gene

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