Aliases for ALDH1B1 Gene
External Ids for ALDH1B1 Gene
Previous HGNC Symbols for ALDH1B1 Gene
Previous GeneCards Identifiers for ALDH1B1 Gene
This protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. This gene does not contain introns in the coding sequence. The variation of this locus may affect the development of alcohol-related problems. [provided by RefSeq, Jul 2008]
GeneCards Summary for ALDH1B1 Gene
ALDH1B1 (Aldehyde Dehydrogenase 1 Family Member B1) is a Protein Coding gene. Diseases associated with ALDH1B1 include Cyclothymic Disorder and Coffin-Siris Syndrome 3. Among its related pathways are Histidine metabolism and beta-Alanine metabolism (KEGG). Gene Ontology (GO) annotations related to this gene include oxidoreductase activity and aldehyde dehydrogenase (NAD) activity. An important paralog of this gene is ALDH2.
UniProtKB/Swiss-Prot for ALDH1B1 Gene
ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation.