Aliases for AKIRIN2 Gene
External Ids for AKIRIN2 Gene
Previous HGNC Symbols for AKIRIN2 Gene
Previous GeneCards Identifiers for AKIRIN2 Gene
GeneCards Summary for AKIRIN2 Gene
AKIRIN2 (Akirin 2) is a Protein Coding gene. Diseases associated with AKIRIN2 include Tick Infestation and Brachydactyly, Type B2. Gene Ontology (GO) annotations related to this gene include enzyme binding. An important paralog of this gene is AKIRIN1.
UniProtKB/Swiss-Prot Summary for AKIRIN2 Gene
Required for the innate immune response. Downstream effector of the Toll-like receptor (TLR), TNF and IL-1 beta signaling pathways leading to the production of IL-6. Forms a complex with YWHAB that acts to repress transcription of DUSP1 (By similarity).