Aliases for AKAP3 Gene
External Ids for AKAP3 Gene
Previous GeneCards Identifiers for AKAP3 Gene
This gene encodes a member of A-kinase anchoring proteins (AKAPs), a family of functionally related proteins that target protein kinase A to discrete locations within the cell. The encoded protein is reported to participate in protein-protein interactions with the R-subunit of the protein kinase A as well as sperm-associated proteins. This protein is expressed in spermatozoa and localized to the acrosomal region of the sperm head as well as the length of the principal piece. It may function as a regulator of motility, capacitation, and the acrosome reaction. [provided by RefSeq, May 2013]
GeneCards Summary for AKAP3 Gene
AKAP3 (A-Kinase Anchoring Protein 3) is a Protein Coding gene. Among its related pathways are Activation of cAMP-Dependent PKA and DAG and IP3 signaling. Gene Ontology (GO) annotations related to this gene include protein kinase A binding. An important paralog of this gene is AKAP4.
UniProtKB/Swiss-Prot Summary for AKAP3 Gene
May function as a regulator of both motility- and head-associated functions such as capacitation and the acrosome reaction.