Aliases for AK9 Gene
External Ids for AK9 Gene
Previous HGNC Symbols for AK9 Gene
Previous GeneCards Identifiers for AK9 Gene
The protein encoded by this gene catalyzes the interconversion of nucleosides, possessing both nucleoside monophosphate and diphosphate kinase activities. The encoded protein uses these interconversions to maintain nucleoside homeostasis. [provided by RefSeq, Jul 2016]
GeneCards Summary for AK9 Gene
AK9 (Adenylate Kinase 9) is a Protein Coding gene. Diseases associated with AK9 include Postsynaptic Congenital Myasthenic Syndromes and Charcot-Marie-Tooth Disease, Type 4J. Among its related pathways are Pyrimidine metabolism (KEGG) and Metabolism. Gene Ontology (GO) annotations related to this gene include nucleoside diphosphate kinase activity and nucleoside monophosphate kinase activity.
UniProtKB/Swiss-Prot for AK9 Gene
Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has both nucleoside monophosphate and diphosphate kinase activities. Catalyzes the phosphorylation of AMP, dAMP, CMP and dCMP with ATP as phosphate donor and of CMP with GTP as phosphate donor. Also catalyzes the production of ATP, CTP, GTP, UTP, dATP, dCTP, dGTP and TTP from the corresponding diphosphate substrates with either ATP or GTP as phosphate donor. Shows substrate preference of CDP > UDP > ADP > GDP > TDP.