Aliases for AK3 Gene
External Ids for AK3 Gene
Previous HGNC Symbols for AK3 Gene
Previous GeneCards Identifiers for AK3 Gene
The protein encoded by this gene is a GTP:ATP phosphotransferase that is found in the mitochondrial matrix. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Dec 2010]
GeneCards Summary for AK3 Gene
AK3 (Adenylate Kinase 3) is a Protein Coding gene. Diseases associated with AK3 include Orofacial Cleft 8 and Reticular Dysgenesis. Among its related pathways are Metabolism of nucleotides and Factors involved in megakaryocyte development and platelet production. Gene Ontology (GO) annotations related to this gene include GTP binding and phosphotransferase activity, phosphate group as acceptor. An important paralog of this gene is AK4.
UniProtKB/Swiss-Prot Summary for AK3 Gene
Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.