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Aliases for AIRN Gene

Subcategory (RNA class) for AIRN Gene


Quality Score for this RNA gene is


Aliases for AIRN Gene

  • Antisense Of IGF2R Non-Protein Coding RNA 2 3 5
  • IGF2R Antisense RNA 1 (Non-Protein Coding) 2 3
  • Antisense Of IGF2R RNA (Non-Protein Coding) 2
  • Non-Protein Coding RNA 88 2
  • NCRNA00088 3
  • IGF2R-AS1 3
  • IGF2R-AS 3
  • IGF2RAS 3
  • AIR 3

External Ids for AIRN Gene

ORGUL Members for AIRN Gene

Previous GeneCards Identifiers for AIRN Gene

  • GC00U922835
  • GC06U901606
  • GC06M160424

Summaries for AIRN Gene

Entrez Gene Summary for AIRN Gene

  • Both spliced and un-spliced long non-coding RNAs are transcribed from this gene. This gene overlaps on the opposite strand the second intron of the insulin-like growth factor 2 receptor gene; a CpG island associated with the second intron denotes an active promoter that drives the expression of this gene. The related mouse gene is responsible for silencing the insulin-like growth factor 2 receptor gene and flanking genes in the imprinted gene cluster of mice. This gene may be expressed in Wilms tumors. [provided by RefSeq, Feb 2013]

GeneCards Summary for AIRN Gene

AIRN (Antisense Of IGF2R Non-Protein Coding RNA) is an RNA Gene, and is affiliated with the antisense RNA class. Diseases associated with AIRN include Wilms Tumor 1.

Additional gene information for AIRN Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for AIRN Gene

Genomics for AIRN Gene

GeneHancer (GH) Regulatory Elements for AIRN Gene

Promoters and enhancers for AIRN Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH06J160006 Enhancer 0.8 FANTOM5 Ensembl 650.7 +1.4 1446 0.4 ZNF202 EHMT2 ZBTB33 REST CHAMP1 AIRN MAP3K4 MAS1 ENSG00000236823 WTAP SLC22A1 IGF2R
GH06J159988 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 0.4 +18.0 17981 2.3 HDGF TCF12 ZNF766 ARID2 ZNF143 CAVIN1 NCOA1 JUNB REST ZNF592 IGF2R MAS1 WTAP ENSG00000236823 SOD2 SLC22A1 AIRN
GH06J159975 Enhancer 1.8 FANTOM5 Ensembl ENCODE dbSUPER 0.3 +26.6 26581 10.2 HDGF PKNOX1 SMAD1 ARID4B SIN3A FEZF1 ZNF2 IRF4 YY1 ZNF207 IGF2R WTAP MAS1 SOD2 ENSG00000236823 SLC22A1 AIRN
GH06J159972 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 0.3 +33.8 33769 3.4 PKNOX1 ATF1 ARNT FEZF1 DMAP1 YY1 TCF12 ZNF766 FOS ATF7 IGF2R WTAP SOD2 SLC22A1 LOC729603 MAS1 AIRN
GH06J159999 Enhancer 1 ENCODE dbSUPER 0.4 +8.2 8190 0.5 HDAC1 TCF12 ATF7 CEBPB NCOA1 ZEB2 ZNF592 SMARCA4 IKZF1 KDM1A WTAP LOC729603 MAP3K4 IGF2R SLC22A1 AIRN
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around AIRN on UCSC Golden Path with GeneCards custom track

Genomic Locations for AIRN Gene

Genomic Locations for AIRN Gene
4,374 bases
Minus strand
4,374 bases
Minus strand

Genomic View for AIRN Gene

Genes around AIRN on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
AIRN Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for AIRN Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for AIRN Gene

Proteins for AIRN Gene

Post-translational modifications for AIRN Gene

No Post-translational modifications

No data available for DME Specific Peptides for AIRN Gene

Domains & Families for AIRN Gene

Gene Families for AIRN Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with AIRN: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for AIRN Gene

Function for AIRN Gene

Phenotypes From GWAS Catalog for AIRN Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for AIRN Gene

Localization for AIRN Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for AIRN Gene

Pathways & Interactions for AIRN Gene

No Data Available

Interacting Proteins for AIRN Gene

Gene Ontology (GO) - Biological Process for AIRN Gene


No data available for Pathways by source and SIGNOR curated interactions for AIRN Gene

Drugs & Compounds for AIRN Gene

No Compound Related Data Available

Transcripts for AIRN Gene

mRNA/cDNA for AIRN Gene

(3) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :
(2) RNA Central transcripts :

Unigene Clusters for AIRN Gene

Antisense of IGF2R non-protein coding RNA:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for AIRN Gene

No ASD Table

Relevant External Links for AIRN Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for AIRN Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for AIRN Gene

mRNA differential expression in normal tissues according to GTEx for AIRN Gene

This gene is overexpressed in Brain - Frontal Cortex (BA9) (x6.7), Brain - Anterior cingulate cortex (BA24) (x6.4), Brain - Cortex (x6.0), and Brain - Hypothalamus (x4.0).

NURSA nuclear receptor signaling pathways regulating expression of AIRN Gene:


SOURCE GeneReport for Unigene cluster for AIRN Gene:

genes like me logo Genes that share expression patterns with AIRN: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for AIRN Gene

Orthologs for AIRN Gene

Evolution for AIRN Gene

Gene Tree for AIRN (if available)
Gene Tree for AIRN (if available)

No data available for Orthologs for AIRN Gene

Paralogs for AIRN Gene

No data available for Paralogs for AIRN Gene

Variants for AIRN Gene

Sequence variations from dbSNP and Humsavar for AIRN Gene

SNP ID Clin Chr 06 pos Variation AA Info Type
rs1000480997 -- 160,008,042(-) T/C upstream_transcript_variant
rs1000900578 -- 160,002,929(-) A/C downstream_transcript_variant
rs1001188899 -- 160,003,096(-) G/A/T downstream_transcript_variant
rs1002196860 -- 160,004,609(-) G/A/C intron_variant, non_coding_transcript_variant
rs1002698318 -- 160,007,564(-) A/G non_coding_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for AIRN Gene

Variant ID Type Subtype PubMed ID
nsv1074441 CNV deletion 25765185
esv35098 CNV gain 17911159
esv2759484 CNV gain+loss 17122850

Additional Variant Information for AIRN Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for AIRN Gene

Disorders for AIRN Gene

MalaCards: The human disease database

(1) MalaCards diseases for AIRN Gene - From: LncRNADisease

Disorder Aliases PubMed IDs
wilms tumor 1
  • wt1
- elite association - COSMIC cancer census association via MalaCards
Search AIRN in MalaCards View complete list of genes associated with diseases

Additional Disease Information for AIRN

genes like me logo Genes that share disorders with AIRN: view

No data available for UniProtKB/Swiss-Prot and Genatlas for AIRN Gene

Publications for AIRN Gene

  1. Identification of the human homolog of the imprinted mouse Air non-coding RNA. (PMID: 18789384) Yotova IY … Barlow DP (Genomics 2008) 2 3 58
  2. Silencing and transcriptional properties of the imprinted Airn ncRNA are independent of the endogenous promoter. (PMID: 19008856) Stricker SH … Barlow DP (The EMBO journal 2008) 2 3 58
  3. A downstream CpG island controls transcript initiation and elongation and the methylation state of the imprinted Airn macro ncRNA promoter. (PMID: 22396659) Koerner MV … Barlow DP (PLoS genetics 2012) 3 58
  4. Kcnq1ot1: a chromatin regulatory RNA. (PMID: 21345374) Kanduri C (Seminars in cell & developmental biology 2011) 3 58
  5. Long non-coding RNA modifies chromatin: epigenetic silencing by long non-coding RNAs. (PMID: 21915889) Saxena A … Carninci P (BioEssays : news and reviews in molecular, cellular and developmental biology 2011) 3 58

Products for AIRN Gene

Sources for AIRN Gene

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