Aliases for AHSG Gene
External Ids for AHSG Gene
Previous GeneCards Identifiers for AHSG Gene
The protein encoded by this gene is a negatively-charged serum glycoprotein that is synthesized by hepatocytes. The encoded protein consists of two polypeptide chains, which are both cleaved from a proprotein encoded from a single mRNA. It is involved in several processes, including endocytosis, brain development, and the formation of bone tissue. Defects in this gene are a cause of susceptibility to leanness. [provided by RefSeq, Aug 2017]
GeneCards Summary for AHSG Gene
AHSG (Alpha 2-HS Glycoprotein) is a Protein Coding gene. Diseases associated with AHSG include Alopecia-Mental Retardation Syndrome 1 and Alopecia-Intellectual Disability Syndrome. Among its related pathways are Innate Immune System and Response to elevated platelet cytosolic Ca2+. Gene Ontology (GO) annotations related to this gene include cysteine-type endopeptidase inhibitor activity and kinase inhibitor activity. An important paralog of this gene is FETUB.
UniProtKB/Swiss-Prot Summary for AHSG Gene
Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions.