Aliases for AHCYL2 Gene
External Ids for AHCYL2 Gene
Previous GeneCards Identifiers for AHCYL2 Gene
The protein encoded by this gene acts as a homotetramer and may be involved in the conversion of S-adenosyl-L-homocysteine to L-homocysteine and adenosine. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
GeneCards Summary for AHCYL2 Gene
AHCYL2 (Adenosylhomocysteinase Like 2) is a Protein Coding gene. Diseases associated with AHCYL2 include Mitochondrial Trifunctional Protein Deficiency. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and One carbon pool by folate. Gene Ontology (GO) annotations related to this gene include NAD binding and adenosylhomocysteinase activity. An important paralog of this gene is AHCYL1.
UniProtKB/Swiss-Prot Summary for AHCYL2 Gene
May regulate the electrogenic sodium/bicarbonate cotransporter SLC4A4 activity and Mg(2+)-sensitivity. On the contrary of its homolog AHCYL1, does not regulate ITPR1 sensitivity to inositol 1,4,5-trisphosphate (PubMed:19220705).