Aliases for AGTPBP1 Gene
External Ids for AGTPBP1 Gene
Previous GeneCards Identifiers for AGTPBP1 Gene
NNA1 is a zinc carboxypeptidase that contains nuclear localization signals and an ATP/GTP-binding motif that was initially cloned from regenerating spinal cord neurons of the mouse.[supplied by OMIM, Jul 2002]
GeneCards Summary for AGTPBP1 Gene
AGTPBP1 (ATP/GTP Binding Protein 1) is a Protein Coding gene. Among its related pathways are Neuroscience. Gene Ontology (GO) annotations related to this gene include binding and metallocarboxypeptidase activity. An important paralog of this gene is AGBL1.
UniProtKB/Swiss-Prot for AGTPBP1 Gene
Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5.