Aliases for AGPAT5 Gene
- 1-Acylglycerol-3-Phosphate O-Acyltransferase 5 2 3 4 5
- 1-Acylglycerol-3-Phosphate O-Acyltransferase 5 (Lysophosphatidic Acid Acyltransferase, Epsilon) 2 3
- Lysophosphatidic Acid Acyltransferase Epsilon 3 4
- 1-AGP Acyltransferase 5 3 4
- 1-AGPAT 5 3 4
- 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase Epsilon 3
- Lysophosphatidic Acid Acyltransferase, Epsilon 2
External Ids for AGPAT5 Gene
Previous GeneCards Identifiers for AGPAT5 Gene
This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. This integral membrane protein converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. A pseudogene of this gene is present on the Y chromosome. [provided by RefSeq, Aug 2014]
GeneCards Summary for AGPAT5 Gene
AGPAT5 (1-Acylglycerol-3-Phosphate O-Acyltransferase 5) is a Protein Coding gene. Diseases associated with AGPAT5 include Keloid Formation. Among its related pathways are Acyl chain remodelling of PE and Glycerolipid metabolism. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring acyl groups and 1-acylglycerol-3-phosphate O-acyltransferase activity. An important paralog of this gene is LCLAT1.
UniProtKB/Swiss-Prot for AGPAT5 Gene
Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Acts on LPA containing saturated or unsaturated fatty acids C15:0-C20:4 at the sn-1 position using C18:1-CoA as the acyl donor. Also acts on lysophosphatidylethanolamine using oleoyl-CoA, but not arachidonoyl-CoA, and lysophosphatidylinositol using arachidonoyl-CoA, but not oleoyl-CoA. Activity toward lysophosphatidylglycerol not detectable.