Aliases for AGPAT4 Gene
- 1-Acylglycerol-3-Phosphate O-Acyltransferase 4 2 3 4 5
- 1-Acylglycerol-3-Phosphate O-Acyltransferase 4 (Lysophosphatidic Acid Acyltransferase, Delta) 2 3
- 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase Delta 3 4
- Lysophosphatidic Acid Acyltransferase Delta 3 4
- 1-AGP Acyltransferase 4 3 4
- LPAAT-Delta 3 4
External Ids for AGPAT4 Gene
Previous GeneCards Identifiers for AGPAT4 Gene
This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. This integral membrane protein converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. [provided by RefSeq, Jul 2008]
GeneCards Summary for AGPAT4 Gene
AGPAT4 (1-Acylglycerol-3-Phosphate O-Acyltransferase 4) is a Protein Coding gene. Among its related pathways are Phospholipase D signaling pathway and Metabolism. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring acyl groups and 1-acylglycerol-3-phosphate O-acyltransferase activity. An important paralog of this gene is AGPAT3.
UniProtKB/Swiss-Prot Summary for AGPAT4 Gene
Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone (By similarity). Exhibits high acyl-CoA specificity for polyunsaturated fatty acyl-CoA, especially docosahexaenoyl-CoA (22:6-CoA, DHA-CoA) (By similarity).