Aliases for AGMO Gene
External Ids for AGMO Gene
Previous HGNC Symbols for AGMO Gene
The protein encoded by this gene is a tetrahydrobiopterin- and iron-dependent enzyme that cleaves the ether bond of alkylglycerols. Sequence comparisons distinguish this protein as forming a third, distinct class of tetrahydrobiopterin-dependent enzymes. Variations in this gene have been associated with decreased glucose-stimulated insulin response, type 2 diabetes, and susceptibility to intracranial aneurysms. [provided by RefSeq, Aug 2012]
GeneCards Summary for AGMO Gene
AGMO (Alkylglycerol Monooxygenase) is a Protein Coding gene. Diseases associated with AGMO include Visceral Leishmaniasis. Among its related pathways are Metabolism and Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha). Gene Ontology (GO) annotations related to this gene include oxidoreductase activity and glyceryl-ether monooxygenase activity.
UniProtKB/Swiss-Prot for AGMO Gene
Glyceryl-ether monooxygenase that cleaves the O-alkyl bond of ether lipids. Ether lipids are essential components of brain membranes.