Aliases for AGBL3 Gene
External Ids for AGBL3 Gene
Previous GeneCards Identifiers for AGBL3 Gene
GeneCards Summary for AGBL3 Gene
AGBL3 (ATP/GTP Binding Protein Like 3) is a Protein Coding gene. Diseases associated with AGBL3 include Cataract 11, Multiple Types and Internal Hemorrhoid. Gene Ontology (GO) annotations related to this gene include metallocarboxypeptidase activity. An important paralog of this gene is AGBL2.
UniProtKB/Swiss-Prot Summary for AGBL3 Gene
Metallocarboxypeptidase that mediates both deglutamylation and deaspartylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates or polyaspartates from the carboxy-terminus of target proteins such as MYLK. Does not show detyrosinase or deglycylase activities from the carboxy-terminus of tubulin.
[Isoform 2]: Metallocarboxypeptidase that mediates tubulin deglutamylation.