Aliases for AGBL2 Gene
External Ids for AGBL2 Gene
Previous GeneCards Identifiers for AGBL2 Gene
GeneCards Summary for AGBL2 Gene
AGBL2 (ATP/GTP Binding Protein Like 2) is a Protein Coding gene. Diseases associated with AGBL2 include Cataract 31, Multiple Types and Cardiofaciocutaneous Syndrome 2. Gene Ontology (GO) annotations related to this gene include metallocarboxypeptidase activity. An important paralog of this gene is AGBL3.
UniProtKB/Swiss-Prot Summary for AGBL2 Gene
Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Does not show detyrosinase or deglycylase activities from the carboxy-terminus of tubulin.