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Aliases for AGAP7P Gene

Aliases for AGAP7P Gene

  • ArfGAP With GTPase Domain, Ankyrin Repeat And PH Domain 7, Pseudogene 2 3 5
  • Arf-GAP With GTPase, ANK Repeat And PH Domain-Containing Protein 7 Pseudogene 3 4
  • Putative Arf-GAP With GTPase, ANK Repeat And PH Domain-Containing Protein 7 3 4
  • Centaurin, Gamma-Like Family, Member 4 2 3
  • CTGLF4 3 4
  • AGAP-7 3 4
  • AGAP7 3 4
  • ArfGAP With GTPase Domain, Ankyrin Repeat And PH Domain 7 2
  • Centaurin-Gamma-Like Family Member 4 4
  • BA109G10.1 3

External Ids for AGAP7P Gene

Previous HGNC Symbols for AGAP7P Gene

  • CTGLF4
  • AGAP7

Summaries for AGAP7P Gene

GeneCards Summary for AGAP7P Gene

AGAP7P (ArfGAP With GTPase Domain, Ankyrin Repeat And PH Domain 7, Pseudogene) is a Pseudogene. Gene Ontology (GO) annotations related to this gene include GTPase activator activity. An important paralog of this gene is LOC101060581.

UniProtKB/Swiss-Prot for AGAP7P Gene

Additional gene information for AGAP7P Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for AGAP7P Gene

Genomics for AGAP7P Gene

GeneHancer (GH) Regulatory Elements for AGAP7P Gene

Promoters and enhancers for AGAP7P Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH10J046017 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 32.5 -87.7 -87659 8.4 ZNF652 ZFX CC2D1A ELF3 MNT CBFA2T2 NKRF POLR2A MLLT1 ZNF121 NCOA4 AGAP4 AGAP7P MSMB PARGP1 ENSG00000229227 GC10M046012 PIR52076
GH10J046028 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 30.7 -79.1 -79083 4.8 CC2D1A CTCF ELF3 ZFX CBFA2T2 NKRF POLR2A MLLT1 CEBPG RERE LOC105378287 NCOA4 MARCH8 AGAP4 AGAP7P GC10M046012 PIR52076
GH10J046000 Enhancer 1.2 ENCODE dbSUPER 30.3 -107.3 -107285 3.5 ZNF652 CC2D1A ELF3 ZKSCAN8 CBFA2T2 ZNF148 POLR2A MLLT1 GTF2F1 CDC5L GC10P046001 PIR61640 PIR61931 AGAP7P AGAP4 TIMM23
GH10J046091 Promoter/Enhancer 1.8 EPDnew FANTOM5 ENCODE dbSUPER 18.8 -14.9 -14878 7 ELF3 CEBPG CDC5L TFE3 MLLT1 IKZF1 GLIS2 IKZF2 ZIC2 GATAD2A MSMB NCOA4 AGAP7P BMS1P1 SHLD2P1 TIMM23 GC10M046105 PIR51454 RPL23AP61
GH10J046052 Enhancer 1.4 FANTOM5 Ensembl ENCODE 22.1 -55.7 -55695 5.6 ZNF652 ELF3 CBFA2T2 RERE AHR ZNF24 TFE3 HNF1A PPARG SP5 AGAP7P MSMB NCOA4 RPL23AP61
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around AGAP7P on UCSC Golden Path with GeneCards custom track

Genomic Locations for AGAP7P Gene

Genomic Locations for AGAP7P Gene
22,184 bases
Plus strand
22,166 bases
Minus strand

Genomic View for AGAP7P Gene

Genes around AGAP7P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
AGAP7P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for AGAP7P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for AGAP7P Gene

Proteins for AGAP7P Gene

  • Protein details for AGAP7P Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Putative Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 7
    Protein Accession:
    Secondary Accessions:
    • A6NGH4

    Protein attributes for AGAP7P Gene

    663 amino acids
    Molecular mass:
    73211 Da
    Quaternary structure:
    No Data Available
    • Encoded by one of the numerous copies of centaurin gamma-like genes clustered in the q11 region of chromosome 10.

neXtProt entry for AGAP7P Gene

Post-translational modifications for AGAP7P Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for AGAP7P Gene

Domains & Families for AGAP7P Gene

Suggested Antigen Peptide Sequences for AGAP7P Gene

GenScript: Design optimal peptide antigens:
  • Centaurin-gamma-like family member 4 (AGAP7_HUMAN)

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the centaurin gamma-like family.
  • Belongs to the centaurin gamma-like family.
genes like me logo Genes that share domains with AGAP7P: view

Function for AGAP7P Gene

Molecular function for AGAP7P Gene

UniProtKB/Swiss-Prot Function:
Putative GTPase-activating protein.

Phenotypes From GWAS Catalog for AGAP7P Gene

Gene Ontology (GO) - Molecular Function for AGAP7P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005096 GTPase activator activity IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with AGAP7P: view
genes like me logo Genes that share phenotypes with AGAP7P: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for AGAP7P

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for AGAP7P Gene

Localization for AGAP7P Gene

Gene Ontology (GO) - Cellular Components for AGAP7P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IBA 21873635
genes like me logo Genes that share ontologies with AGAP7P: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for AGAP7P Gene

Pathways & Interactions for AGAP7P Gene

PathCards logo

SuperPathways for AGAP7P Gene

No Data Available

Interacting Proteins for AGAP7P Gene

Selected Interacting proteins: Q5VUJ5-AGAP7_HUMAN for AGAP7P Gene via IID

Gene Ontology (GO) - Biological Process for AGAP7P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0043547 positive regulation of GTPase activity IEA --
genes like me logo Genes that share ontologies with AGAP7P: view

No data available for Pathways by source and SIGNOR curated interactions for AGAP7P Gene

Drugs & Compounds for AGAP7P Gene

No Compound Related Data Available

Transcripts for AGAP7P Gene

mRNA/cDNA for AGAP7P Gene

(1) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for AGAP7P

Alternative Splicing Database (ASD) splice patterns (SP) for AGAP7P Gene

No ASD Table

Relevant External Links for AGAP7P Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for AGAP7P Gene

Protein differential expression in normal tissues from HIPED for AGAP7P Gene

This gene is overexpressed in Brain (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for AGAP7P Gene

Protein tissue co-expression partners for AGAP7P Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of AGAP7P Gene:


Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for AGAP7P Gene

Orthologs for AGAP7P Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for AGAP7P Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia CTGLF2 34
  • 97.94 (n)
Species where no ortholog for AGAP7P was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for AGAP7P Gene

Gene Tree for AGAP7P (if available)
Gene Tree for AGAP7P (if available)

Paralogs for AGAP7P Gene

Paralogs for AGAP7P Gene

genes like me logo Genes that share paralogs with AGAP7P: view

Variants for AGAP7P Gene

Sequence variations from dbSNP and Humsavar for AGAP7P Gene

SNP ID Clin Chr 10 pos Variation AA Info Type
rs1001422900 -- 46,107,878(+) C/G upstream_transcript_variant
rs1010182860 -- 46,107,679(+) G/T upstream_transcript_variant
rs1014145565 -- 46,108,222(+) G/T upstream_transcript_variant
rs1015085421 -- 46,107,905(+) C/T upstream_transcript_variant
rs1021416698 -- 46,107,856(+) G/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for AGAP7P Gene

Variant ID Type Subtype PubMed ID
esv22941 CNV loss 19812545
esv3577172 CNV gain 25503493
nsv1042912 CNV loss 25217958
nsv508583 CNV deletion 20534489
nsv510992 OTHER complex 20534489
nsv947992 CNV duplication 23825009
nsv950957 CNV deletion 24416366
nsv950958 CNV deletion 24416366
nsv975697 CNV duplication 23825009
nsv975699 CNV duplication 23825009
nsv975700 CNV duplication 23825009
nsv982768 CNV duplication 23825009

Variation tolerance for AGAP7P Gene

Gene Damage Index Score: 17.70; 98.30% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for AGAP7P Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for AGAP7P Gene

Disorders for AGAP7P Gene

Additional Disease Information for AGAP7P

No disorders were found for AGAP7P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for AGAP7P Gene

Publications for AGAP7P Gene

  1. The functional landscape of Hsp27 reveals new cellular processes such as DNA repair and alternative splicing and proposes novel anticancer targets. (PMID: 25277244) Katsogiannou M … Rocchi P (Molecular & cellular proteomics : MCP 2014) 3 58
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3 58
  3. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P … Rogers J (Nature 2004) 4 58
  4. Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence. (PMID: 7566098) Adams MD … White O (Nature 1995) 3 58

Products for AGAP7P Gene

Sources for AGAP7P Gene

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