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Aliases for AGAP2-AS1 Gene

Subcategory (RNA class) for AGAP2-AS1 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for AGAP2-AS1 Gene

  • AGAP2 Antisense RNA 1 2 3 5
  • PUNISHER 3

External Ids for AGAP2-AS1 Gene

Previous GeneCards Identifiers for AGAP2-AS1 Gene

  • GC12P058122
  • GC12P058123

Summaries for AGAP2-AS1 Gene

GeneCards Summary for AGAP2-AS1 Gene

AGAP2-AS1 (AGAP2 Antisense RNA 1) is an RNA Gene, and is affiliated with the non-coding RNA class.

Additional gene information for AGAP2-AS1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for AGAP2-AS1 Gene

Genomics for AGAP2-AS1 Gene

GeneHancer (GH) Regulatory Elements for AGAP2-AS1 Gene

Promoters and enhancers for AGAP2-AS1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH12I057725 Promoter/Enhancer 1.5 Ensembl ENCODE 550.8 +0.5 499 1.9 ARID4B SIN3A ZNF2 ZBTB7B GLIS2 ELK1 ZNF143 KLF7 KLF13 SP3 AGAP2-AS1 GC12M057724 ZBTB39 NAB2 PRIM1 NEMP1 ENSG00000224713 ATP23 TSPAN31 AGAP2
GH12I057727 Enhancer 0.5 ENCODE 550.8 +1.6 1573 0.2 ZNF143 SIN3A MIER2 REST ZNF600 EZH2 AGAP2-AS1 AGAP2 TSPAN31
GH12I057109 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE dbSUPER 31.2 -615.0 -614986 3.8 CLOCK FEZF1 DMAP1 IRF4 YY1 ZNF213 ZNF416 ZNF143 ZNF548 MCM3 STAT6 NEMP1 EEF1AKMT3 ENSG00000257740 BAZ2A PAN2 SMARCC2 ANKRD52 CDK4 CTDSP2
GH12I057487 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 11.6 -237.6 -237577 2.9 HDGF PKNOX1 SMAD1 ARID4B SIN3A FEZF1 DMAP1 YY1 POLR2B ZNF766 ARHGAP9 MARS BAZ2A NEMP1 MBD6 RN7SL809P PRIM1 EEF1AKMT3 CTDSP2 CDK4
GH12I057516 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 10 -205.2 -205151 8.8 CLOCK FEZF1 DMAP1 YBX1 YY1 SLC30A9 ZNF213 E2F8 ZNF143 SP3 MBD6 DDIT3 MIR616 NEMP1 BAZ2A RN7SL809P EEF1AKMT3 DTX3 CDK4 CTDSP2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around AGAP2-AS1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for AGAP2-AS1 Gene

Genomic Locations for AGAP2-AS1 Gene
chr12:57,726,240-57,728,356
(GRCh38/hg38)
Size:
2,117 bases
Orientation:
Plus strand
chr12:58,120,023-58,122,139
(GRCh37/hg19)

Genomic View for AGAP2-AS1 Gene

Genes around AGAP2-AS1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
AGAP2-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for AGAP2-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for AGAP2-AS1 Gene

Proteins for AGAP2-AS1 Gene

Post-translational modifications for AGAP2-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for AGAP2-AS1 Gene

Domains & Families for AGAP2-AS1 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for AGAP2-AS1 Gene

Function for AGAP2-AS1 Gene

Phenotypes From GWAS Catalog for AGAP2-AS1 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for AGAP2-AS1 Gene

Localization for AGAP2-AS1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for AGAP2-AS1 Gene

Pathways & Interactions for AGAP2-AS1 Gene

SuperPathways for AGAP2-AS1 Gene

No Data Available

Interacting Proteins for AGAP2-AS1 Gene

Gene Ontology (GO) - Biological Process for AGAP2-AS1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for AGAP2-AS1 Gene

Drugs & Compounds for AGAP2-AS1 Gene

No Compound Related Data Available

Transcripts for AGAP2-AS1 Gene

mRNA/cDNA for AGAP2-AS1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for AGAP2-AS1 Gene

No ASD Table

Relevant External Links for AGAP2-AS1 Gene

GeneLoc Exon Structure for
AGAP2-AS1
ECgene alternative splicing isoforms for
AGAP2-AS1

Expression for AGAP2-AS1 Gene

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for AGAP2-AS1 Gene

Orthologs for AGAP2-AS1 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for AGAP2-AS1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia AGAP2-AS1 34
  • 100 (a)
OneToOne
Species where no ortholog for AGAP2-AS1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for AGAP2-AS1 Gene

ENSEMBL:
Gene Tree for AGAP2-AS1 (if available)
TreeFam:
Gene Tree for AGAP2-AS1 (if available)

Paralogs for AGAP2-AS1 Gene

No data available for Paralogs for AGAP2-AS1 Gene

Variants for AGAP2-AS1 Gene

Sequence variations from dbSNP and Humsavar for AGAP2-AS1 Gene

SNP ID Clin Chr 12 pos Variation AA Info Type
rs1000812250 -- 57,726,177(+) T/A upstream_transcript_variant
rs1001238887 -- 57,726,463(+) G/A/C intron_variant
rs1002130774 -- 57,725,259(+) G/C upstream_transcript_variant
rs1003621192 -- 57,724,857(+) C/G/T upstream_transcript_variant
rs1003699616 -- 57,728,249(+) G/A non_coding_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for AGAP2-AS1 Gene

Variant ID Type Subtype PubMed ID
nsv470296 CNV loss 18288195
nsv559045 CNV loss 21841781
nsv826383 CNV gain 20364138

Variation tolerance for AGAP2-AS1 Gene

Gene Damage Index Score: 0.48; 10.55% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for AGAP2-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
AGAP2-AS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for AGAP2-AS1 Gene

Disorders for AGAP2-AS1 Gene

Additional Disease Information for AGAP2-AS1

No disorders were found for AGAP2-AS1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for AGAP2-AS1 Gene

Publications for AGAP2-AS1 Gene

  1. Upregulated long non-coding RNA AGAP2-AS1 represses LATS2 and KLF2 expression through interacting with EZH2 and LSD1 in non-small-cell lung cancer cells. (PMID: 27195672) Li W … Shu Y (Cell death & disease 2016) 2 3 58
  2. Co-expression Network Analysis of Human lncRNAs and Cancer Genes. (PMID: 25392693) Cogill SB … Wang L (Cancer informatics 2014) 2 3 58
  3. Long noncoding AGAP2-AS1 is activated by SP1 and promotes cell proliferation and invasion in gastric cancer. (PMID: 28209205) Qi F … Wang K (Journal of hematology & oncology 2017) 3 58
  4. Identification of novel long noncoding RNAs underlying vertebrate cardiovascular development. (PMID: 25739401) Kurian L … Belmonte JCI (Circulation 2015) 3 58
  5. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PMID: 15146197) Brandenberger R … Stanton LW (Nature biotechnology 2004) 3 58

Products for AGAP2-AS1 Gene

Sources for AGAP2-AS1 Gene

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