Aliases for AGAP2-AS1 Gene
Subcategory (RNA class) for AGAP2-AS1 Gene
non-coding RNA
Quality Score for this RNA gene is
13
External Ids for AGAP2-AS1 Gene
- HGNC: 48633
- Entrez Gene: 100130776
- Ensembl: ENSG00000255737
Previous GeneCards Identifiers for AGAP2-AS1 Gene
- GC12P058122
- GC12P058123
Summaries for AGAP2-AS1 Gene
GeneCards Summary for AGAP2-AS1 Gene
AGAP2-AS1 (AGAP2 Antisense RNA 1) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with AGAP2-AS1 include Lung Cancer and Gastric Cancer.
Additional gene information for AGAP2-AS1 Gene
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for AGAP2-AS1 Gene
Genomics for AGAP2-AS1 Gene
GeneHancer (GH) Regulatory Elements for AGAP2-AS1 Gene
Promoters and enhancers for AGAP2-AS1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around AGAP2-AS1 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for AGAP2-AS1 Gene
Genomic Locations for AGAP2-AS1 Gene
- chr12:57,726,240-57,728,356
- (GRCh38/hg38)
- Size:
- 2,117 bases
- Orientation:
- Plus strand
- chr12:58,120,023-58,122,139
- (GRCh37/hg19)
- Size:
- 2,117 bases
- Orientation:
- Plus strand
Genomic View for AGAP2-AS1 Gene
Genes around AGAP2-AS1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 12q14.1 by Entrez Gene
- 12q14.1 by HGNC
- 12q14.1 by Ensembl
AGAP2-AS1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for AGAP2-AS1 Gene
Proteins for AGAP2-AS1 Gene
Post-translational modifications for AGAP2-AS1 Gene
No Post-translational modifications
Antibody Products
- Search GeneTex for Antibodies for AGAP2-AS1
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for AGAP2-AS1
- Origene Custom Protein Services for AGAP2-AS1
- Search GeneTex for Proteins for AGAP2-AS1
No data available for DME Specific Peptides for AGAP2-AS1 Gene
Domains & Families for AGAP2-AS1 Gene
Graphical View of Domain Structure for InterPro Entry
No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for AGAP2-AS1 Gene
Function for AGAP2-AS1 Gene
Phenotypes From GWAS Catalog for AGAP2-AS1 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for AGAP2-AS1
-
miRNA Products
Inhibitory RNA Products
Clone Products
- GenScript: Custom all cDNA clones Services for AGAP2-AS1
- VectorBuilder custom plasmid, inducible vectors for AGAP2-AS1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for AGAP2-AS1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for AGAP2-AS1 Gene
Localization for AGAP2-AS1 Gene
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for AGAP2-AS1 Gene
Transcripts for AGAP2-AS1 Gene
mRNA/cDNA for AGAP2-AS1 Gene
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000542466 1500 bps (uc058qbj.1)
- (2) RNA Central transcripts :
CRISPR Products
- Browse CRISPR knockouts for AGAP2-AS1
miRNA Products
Inhibitory RNA Products
Clone Products
- GenScript: Custom all cDNA clones Services for AGAP2-AS1
- VectorBuilder custom plasmid, inducible vectors for AGAP2-AS1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for AGAP2-AS1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Expression for AGAP2-AS1 Gene
No Expression Related Data Available
Primer Products
Gene Expression Assay Products
No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for AGAP2-AS1 Gene
Orthologs for AGAP2-AS1 Gene
This gene was present in the common ancestor of human and chimp.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | AGAP2-AS1 34 |
|
OneToOne |
- Species where no ortholog for AGAP2-AS1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- cow (Bos Taurus)
- dog (Canis familiaris)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- mouse (Mus musculus)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for AGAP2-AS1 Gene
No data available for Paralogs for AGAP2-AS1 Gene
Variants for AGAP2-AS1 Gene
| SNP ID | Clin | Chr 12 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000812250 | -- | 57,726,177(+) | T/A | upstream_transcript_variant | |
| rs1001238887 | -- | 57,726,463(+) | G/A/C | intron_variant | |
| rs1002130774 | -- | 57,725,259(+) | G/C | upstream_transcript_variant | |
| rs1003621192 | -- | 57,724,857(+) | C/G/T | upstream_transcript_variant | |
| rs1003699616 | -- | 57,728,249(+) | G/A | non_coding_transcript_variant |
Gene Damage Index Score:
0.48;
10.55% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for AGAP2-AS1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- AGAP2-AS1
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for AGAP2-AS1 Gene
Disorders for AGAP2-AS1 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| lung cancer |
|
|
| gastric cancer |
|
Search AGAP2-AS1 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for AGAP2-AS1
No data available for UniProtKB/Swiss-Prot and Genatlas for AGAP2-AS1 Gene
Publications for AGAP2-AS1 Gene
- Upregulated long non-coding RNA AGAP2-AS1 represses LATS2 and KLF2 expression through interacting with EZH2 and LSD1 in non-small-cell lung cancer cells. (PMID: 27195672) Li W … Shu Y (Cell death & disease 2016) 2 3 58
- Co-expression Network Analysis of Human lncRNAs and Cancer Genes. (PMID: 25392693) Cogill SB … Wang L (Cancer informatics 2014) 2 3 58
- Long noncoding AGAP2-AS1 is activated by SP1 and promotes cell proliferation and invasion in gastric cancer. (PMID: 28209205) Qi F … Wang K (Journal of hematology & oncology 2017) 3 58
- Identification of novel long noncoding RNAs underlying vertebrate cardiovascular development. (PMID: 25739401) Kurian L … Belmonte JCI (Circulation 2015) 3 58
- Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PMID: 15146197) Brandenberger R … Stanton LW (Nature biotechnology 2004) 3 58
Products for AGAP2-AS1 Gene
- Browse R&D Systems for Antibodies
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- Browse R&D Systems for biochemical assays
- Browse Human Proteins and Enzymes
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
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- Browse Immunoprecipitation Assays
- Browse Luminex Assays
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- Custom Assay Services
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- Browse CRISPR knockouts for AGAP2-AS1
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- GenScript: Custom all cDNA clones Services for AGAP2-AS1
- GenScript Custom Purified and Recombinant Proteins Services for AGAP2-AS1
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- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Cyagen custom Knockout/knockin (KOKI) mouse models for AGAP2-AS1
- VectorBuilder custom plasmid, inducible vectors for AGAP2-AS1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for AGAP2-AS1
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneTex for Antibodies for AGAP2-AS1
- Search GeneTex for Proteins for AGAP2-AS1
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for knockout CRISPR/Cas9 clones, lentivirus, and/or AAV products for AGAP2-AS1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles, and/or promoter clone products for AGAP2-AS1
- Search GeneCopoeia for miRNA 3'UTR Target clone products for AGAP2-AS1
- Search GeneCopoeia for shRNA, lentivirus, and/or AAV clone products for AGAP2-AS1
Sources for AGAP2-AS1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio
- (169) Biorbyt