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Aliases for AGAP2-AS1 Gene
Subcategory (RNA class) for AGAP2-AS1 Gene
lncRNA
Number of RNA Genes sources:
1 / 14
External Ids for AGAP2-AS1 Gene
- HGNC: 48633
- Entrez Gene: 100130776
- Ensembl: ENSG00000255737
Previous GeneCards Identifiers for AGAP2-AS1 Gene
- GC12P058122
- GC12P058123
Summaries for AGAP2-AS1 Gene
GeneCards Summary for AGAP2-AS1 Gene
AGAP2-AS1 (AGAP2 Antisense RNA 1) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with AGAP2-AS1 include Malignant Glioma and Lung Cancer.
Additional gene information for AGAP2-AS1 Gene
No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for AGAP2-AS1 Gene
Genomics for AGAP2-AS1 Gene
GeneHancer (GH) Regulatory Elements for AGAP2-AS1 Gene
Promoters and enhancers for AGAP2-AS1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around AGAP2-AS1 on UCSC Golden Path with GeneCards custom track
Genomic Locations for AGAP2-AS1 Gene
Genomic Locations for AGAP2-AS1 Gene
- chr12:57,726,239-57,728,356
- (GRCh38/hg38)
- Size:
- 2,118 bases
- Orientation:
- Plus strand
- chr12:58,120,023-58,122,139
- (GRCh37/hg19)
- Size:
- 2,117 bases
- Orientation:
- Plus strand
Genomic View for AGAP2-AS1 Gene
Genes around AGAP2-AS1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 12q14.1 by HGNC
- 12q14.1 by Entrez Gene
- 12q14.1 by Ensembl
AGAP2-AS1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for AGAP2-AS1 Gene
Proteins for AGAP2-AS1 Gene
Post-translational modifications for AGAP2-AS1 Gene
No Post-translational modifications
Antibody Products
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for AGAP2-AS1
- Origene Custom Protein Services for AGAP2-AS1
No data available for DME Specific Peptides for AGAP2-AS1 Gene
Domains & Families for AGAP2-AS1 Gene
Gene Families for AGAP2-AS1 Gene
No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for AGAP2-AS1 Gene
Function for AGAP2-AS1 Gene
Phenotypes From GWAS Catalog for AGAP2-AS1 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
miRNA Products
Inhibitory RNA Products
Clone Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for AGAP2-AS1 Gene
Localization for AGAP2-AS1 Gene
| Compartment | Confidence |
|---|---|
| nucleus | 2 |
| plasma membrane | 1 |
| extracellular | 1 |
| cytoskeleton | 1 |
| cytosol | 1 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for AGAP2-AS1 Gene
Transcripts for AGAP2-AS1 Gene
mRNA/cDNA for AGAP2-AS1 Gene
- 3 RNACentral transcripts :
- 1 REFSEQ mRNAs :
- 5 NCBI additional mRNA sequence :
- 1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000542466 1500 bps (ENST00000542466.2)
- 1 LncBook transcripts :
CRISPR Products
- Browse CRISPR knockouts for AGAP2-AS1
miRNA Products
Inhibitory RNA Products
Clone Products
Relevant External Links for AGAP2-AS1 Gene
- GeneLoc Exon Structure for
- AGAP2-AS1
Expression for AGAP2-AS1 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for AGAP2-AS1
No Expression Related Data Available
Primer Products
Gene Expression Assay Products
No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for AGAP2-AS1 Gene
Orthologs for AGAP2-AS1 Gene
This gene was present in the common ancestor of human and chimp.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | AGAP2-AS1 31 |
|
OneToOne |
- Species where no ortholog for AGAP2-AS1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- cow (Bos Taurus)
- dog (Canis familiaris)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- mouse (Mus musculus)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for AGAP2-AS1 Gene
No data available for Paralogs for AGAP2-AS1 Gene
Variants for AGAP2-AS1 Gene
Gene Damage Index Score:
0.48;
10.55% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for AGAP2-AS1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- AGAP2-AS1
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for AGAP2-AS1 Gene
Disorders for AGAP2-AS1 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| malignant glioma |
|
|
| lung cancer |
|
|
| gastric cancer |
|
Search AGAP2-AS1 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for AGAP2-AS1
No data available for UniProtKB/Swiss-Prot and Genatlas for AGAP2-AS1 Gene
Publications for AGAP2-AS1 Gene
- Long non-coding RNA AGAP2-AS1 exerts oncogenic properties in glioblastoma by epigenetically silencing TFPI2 through EZH2 and LSD1. (PMID: 31186379) Luo W … Zhao S (Aging 2019) 2 3 54
- Upregulated long non-coding RNA AGAP2-AS1 represses LATS2 and KLF2 expression through interacting with EZH2 and LSD1 in non-small-cell lung cancer cells. (PMID: 27195672) Li W … Shu Y (Cell death & disease 2016) 2 3 54
- Co-expression Network Analysis of Human lncRNAs and Cancer Genes. (PMID: 25392693) Cogill SB … Wang L (Cancer informatics 2014) 2 3 54
- The Long Non-Coding RNA (lncRNA) AGAP2-AS1 is Upregulated in Ovarian Carcinoma and Negatively Regulates lncRNA MEG3. (PMID: 31233485) Chen J … Dai Y (Medical science monitor : international medical journal of experimental and clinical research 2019) 3 54
- Long non-coding RNA AGAP2-AS1, functioning as a competitive endogenous RNA, upregulates ANXA11 expression by sponging miR-16-5p and promotes proliferation and metastasis in hepatocellular carcinoma. (PMID: 31088485) Liu Z … Liu Q (Journal of experimental & clinical cancer research : CR 2019) 3 54
Products for AGAP2-AS1 Gene
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Sources for AGAP2-AS1 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) H-invDB
- (47) HORDE
- (48) HUGE
- (49) IMGT
- (50) Leiden
- (51) miRBase
- (52) DME
- (53) OriGene
- (54) PubMed
- (55) R&D Systems
- (56) TGDB
- (57) Tocris
- (58) Abcam
- (59) Novus Biologicals
- (60) ProSpec
- (61) Sino Biological
- (62) GenScript
- (63) Qiagen
- (64) OCA
- (65) Proteopedia
- (66) MOPED
- (67) neXtProt
- (68) Reactome
- (69) GeneGo (Thomson Reuters)
- (70) DISEASES
- (71) SIMAP
- (72) GenomeRNAi
- (73) LifeMap
- (74) miRTarBase
- (75) MalaCards
- (76) Invitrogen
- (77) BitterDB
- (78) ESI-BIO
- (79) RefSeq
- (80) BioSystems
- (81) MaxQB
- (82) IUPHAR
- (83) BioGPS
- (84) Illumina
- (85) COMPARTMENTS
- (86) HOMER
- (87) PaxDb
- (88) ApexBio
- (89) Addgene
- (90) antibodies-online
- (91) CYP
- (92) NONCODE
- (93) TreeFam
- (94) PathCards
- (95) GeneReviews
- (96) GeneTex
- (97) Taconic Biosciences
- (98) GTEx
- (99) ProteomicsDB
- (100) SCBT
- (101) DGIdb
- (102) ClinicalTrials
- (103) RVIS
- (104) SIGNOR
- (105) diseasecard
- (106) NIH Rare Diseases
- (107) Orphanet
- (108) UMLS
- (109) GTR
- (110) Disease Ontology
- (111) Genetics Home Reference
- (112) MeSH
- (113) MedlinePlus
- (114) CDC
- (115) NINDS
- (116) NCBI Bookshelf
- (117) ClinVar
- (118) Gene Damage Index
- (119) HPO
- (120) UDN
- (121) VISTA
- (122) FANTOM5
- (123) ENCODE
- (124) ProSci
- (125) Horizon
- (126) The Signaling Pathways Project (SPP)
- (127) IID
- (128) VectorBuilder
- (129) SNPedia
- (130) BRCA Exchange
- (131) CIViC
- (132) ProteoGenix
- (133) dbSUPER
- (134) TISSUES
- (135) Gene ORGANizer
- (136) abm
- (137) Human Protein Atlas
- (138) GWAS Catalog
- (139) Monarch Initiative
- (140) DataMed
- (141) HumanCyc
- (142) genomics-online
- (143) UCNEbase
- (144) EPDnew
- (145) Applied Biosystems
- (146) GlyConnect
- (147) Aminode
- (148) GeneCopoeia
- (149) GPS-Prot
- (150) RNACentral
- (151) LncRNADisease
- (152) LOVD
- (153) miR2Disease
- (154) DiseaseEnhancer
- (155) Boster Bio
- (156) Biorbyt
- (157) Biocompare
- (158) Mastermind
- (159) CTD^2 Dashboard
- (160) CraniofacialAtlas
- (161) GeneImprint
- (162) Synthego
- (163) Bio Basic
- (164) ENA
- (165) GtRNAdb
- (166) LncBase
- (167) LncBook
- (168) LNCipedia
- (169) LncRNAdb
- (170) Modomics
- (171) PDBe
- (172) Rfam
- (173) SILVA
- (174) snOPY
- (175) SRPDB
- (176) GENCODE
- (177) TarBase
- (178) MyBioSource