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Aliases for AFG3L1P Gene

Aliases for AFG3L1P Gene

  • AFG3 Like Matrix AAA Peptidase Subunit 1, Pseudogene 2 3 5
  • AFG3 Like AAA ATPase 1, Pseudogene 2 3
  • AFG3 ATPase Family Gene 3-Like 1 (S. Cerevisiae), Pseudogene 2
  • AFG3 ATPase Family Member 3-Like 1, Pseudogene 3
  • AFG3 ATPase Family Gene 3-Like 1, Pseudogene 3
  • AFG3 (ATPase Family Gene 3, Yeast)-Like 1 3
  • AFG3L1 3
  • AFG3 3

External Ids for AFG3L1P Gene

Previous HGNC Symbols for AFG3L1P Gene

  • AFG3
  • AFG3L1

Previous GeneCards Identifiers for AFG3L1P Gene

  • GC16P090039
  • GC16P090041

Summaries for AFG3L1P Gene

GeneCards Summary for AFG3L1P Gene

AFG3L1P (AFG3 Like Matrix AAA Peptidase Subunit 1, Pseudogene) is a Pseudogene.

Additional gene information for AFG3L1P Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for AFG3L1P Gene

Genomics for AFG3L1P Gene

GeneHancer (GH) Regulatory Elements for AFG3L1P Gene

Promoters and enhancers for AFG3L1P Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH16J089971 Promoter/Enhancer 1.6 Ensembl ENCODE 673.4 +0.9 883 4.8 HDGF PKNOX1 CLOCK SMAD1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 AFG3L1P CENPBD1 ANKRD11 ENSG00000268218 TCF25 DEF8 MC1R ZNF778 LOC101927863 ENSG00000259006
GH16J089993 Enhancer 1.5 Ensembl ENCODE dbSUPER 117.8 +22.7 22667 3.5 HDGF PKNOX1 CLOCK FOXA2 ARNT ZFP64 ARID4B SIN3A ZNF2 ZBTB7B PIR44838 AFG3L1P ENSG00000259877 ANKRD11 MC1R ACSF3 TCF25 LOC101927863 ENSG00000268218 SNORD68
GH16J089558 Promoter/Enhancer 2.5 EPDnew Ensembl ENCODE dbSUPER 67.6 -410.0 -409954 7.9 CLOCK MLX DMAP1 YY1 SLC30A9 ZNF213 E2F8 ZNF143 SP3 NFYC RPL13 SNORD68 GC16P089560 GC16P089561 PIR32702 ANKRD11 AFG3L1P TCF25 ENSG00000268218 ZC3H18
GH16J089717 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 59 -251.5 -251527 7.5 PKNOX1 MLX ARNT ZFP64 ARID4B SIN3A DMAP1 YY1 POLR2B ZNF766 VPS9D1 ZNF276 AFG3L1P ANKRD11 ENSG00000268218 TCF25 LOC101927863 MC1R ACSF3 CDK10
GH16J089503 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 40 -465.6 -465597 6.1 CLOCK MLX ZFP64 FEZF1 DMAP1 YY1 SLC30A9 E2F8 ZNF143 SP3 SPG7 LOC101927863 AFG3L1P MC1R ANKRD11 ZC3H18 ENSG00000268218 TCF25 RPL13 ENSG00000259877
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around AFG3L1P on UCSC Golden Path with GeneCards custom track

Genomic Locations for AFG3L1P Gene

Genomic Locations for AFG3L1P Gene
chr16:89,972,580-90,002,161
(GRCh38/hg38)
Size:
29,582 bases
Orientation:
Plus strand
chr16:90,038,988-90,068,569
(GRCh37/hg19)
Size:
29,582 bases
Orientation:
Plus strand

Genomic View for AFG3L1P Gene

Genes around AFG3L1P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
AFG3L1P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for AFG3L1P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for AFG3L1P Gene

Proteins for AFG3L1P Gene

Post-translational modifications for AFG3L1P Gene

No Post-translational modifications

No data available for DME Specific Peptides for AFG3L1P Gene

Domains & Families for AFG3L1P Gene

Gene Families for AFG3L1P Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with AFG3L1P: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for AFG3L1P Gene

Function for AFG3L1P Gene

Phenotypes From GWAS Catalog for AFG3L1P Gene

genes like me logo Genes that share phenotypes with AFG3L1P: view

Animal Model Products

  • Taconic Biosciences Mouse Models for AFG3L1P

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for AFG3L1P

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for AFG3L1P Gene

Localization for AFG3L1P Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for AFG3L1P Gene

Pathways & Interactions for AFG3L1P Gene

SuperPathways for AFG3L1P Gene

No Data Available

Interacting Proteins for AFG3L1P Gene

Gene Ontology (GO) - Biological Process for AFG3L1P Gene

None

No data available for Pathways by source and SIGNOR curated interactions for AFG3L1P Gene

Drugs & Compounds for AFG3L1P Gene

No Compound Related Data Available

Transcripts for AFG3L1P Gene

mRNA/cDNA for AFG3L1P Gene

(2) REFSEQ mRNAs :
(17) Additional mRNA sequences :
(88) Selected AceView cDNA sequences:
(17) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for AFG3L1P Gene

AFG3 ATPase family member 3-like 1 (S. cerevisiae), pseudogene:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for AFG3L1P

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for AFG3L1P Gene

No ASD Table

Relevant External Links for AFG3L1P Gene

GeneLoc Exon Structure for
AFG3L1P
ECgene alternative splicing isoforms for
AFG3L1P

Expression for AFG3L1P Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for AFG3L1P Gene

NURSA nuclear receptor signaling pathways regulating expression of AFG3L1P Gene:

AFG3L1P

SOURCE GeneReport for Unigene cluster for AFG3L1P Gene:

Hs.534773
genes like me logo Genes that share expression patterns with AFG3L1P: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for AFG3L1P Gene

Orthologs for AFG3L1P Gene

Evolution for AFG3L1P Gene

ENSEMBL:
Gene Tree for AFG3L1P (if available)
TreeFam:
Gene Tree for AFG3L1P (if available)

No data available for Orthologs for AFG3L1P Gene

Paralogs for AFG3L1P Gene

No data available for Paralogs for AFG3L1P Gene

Variants for AFG3L1P Gene

Sequence variations from dbSNP and Humsavar for AFG3L1P Gene

SNP ID Clin Chr 16 pos Variation AA Info Type
rs1000102112 -- 89,997,657(+) C/G genic_downstream_transcript_variant, intron_variant
rs1000300510 -- 89,997,607(+) T/G genic_downstream_transcript_variant, intron_variant
rs1000353797 -- 89,981,993(+) C/T intron_variant
rs1000464059 -- 89,972,592(+) C/T non_coding_transcript_variant
rs1000492851 -- 89,976,555(+) T/C intron_variant

Structural Variations from Database of Genomic Variants (DGV) for AFG3L1P Gene

Variant ID Type Subtype PubMed ID
nsv952080 CNV deletion 24416366
nsv573842 CNV loss 21841781
nsv573841 CNV loss 21841781
nsv573810 CNV loss 21841781
nsv573799 CNV gain 21841781
nsv482951 CNV loss 15286789
nsv479100 CNV novel sequence insertion 20440878
nsv477114 CNV novel sequence insertion 20440878
nsv471120 CNV gain 18288195
nsv471119 CNV loss 18288195
nsv457626 CNV loss 19166990
nsv428331 CNV gain+loss 18775914
nsv1066499 CNV loss 25217958
nsv103116 CNV deletion 16902084
nsv103059 CNV insertion 16902084
esv3892941 CNV gain 25118596
esv3689 CNV loss 18987735
esv3639605 CNV loss 21293372
esv3639604 CNV loss 21293372
esv3639603 CNV gain 21293372
esv2762221 CNV gain+loss 21179565
esv2664835 CNV deletion 23128226
esv2136699 CNV deletion 18987734

Additional Variant Information for AFG3L1P Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
AFG3L1P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for AFG3L1P Gene

Disorders for AFG3L1P Gene

Additional Disease Information for AFG3L1P

No disorders were found for AFG3L1P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for AFG3L1P Gene

Publications for AFG3L1P Gene

  1. Molecular and functional analyses of the human and mouse genes encoding AFG3L1, a mitochondrial metalloprotease homologous to the human spastic paraplegia protein. (PMID: 11549317) Kremmidiotis G … Callen DF (Genomics 2001) 2 3 22 58
  2. Chromosomal locations of three human nuclear genes (RPSM12, TUFM, and AFG3L1) specifying putative components of the mitochondrial gene expression apparatus. (PMID: 9545647) Shah ZH … Jacobs HT (Genomics 1998) 2 3 22 58
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T … Vidal M (Cell 2014) 3 58
  4. The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control of the cell cycle. (PMID: 21555518) Warnatz HJ … Yaspo ML (The Journal of biological chemistry 2011) 3 58
  5. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) Oláh J … Ovádi J (The Journal of biological chemistry 2011) 3 58

Products for AFG3L1P Gene

Sources for AFG3L1P Gene

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