Aliases for AFG3L1P Gene

Aliases for AFG3L1P Gene

  • AFG3 Like Matrix AAA Peptidase Subunit 1, Pseudogene 2 3 5
  • AFG3 Like AAA ATPase 1, Pseudogene 2 3
  • AFG3 ATPase Family Gene 3-Like 1 (S. Cerevisiae), Pseudogene 2
  • AFG3 ATPase Family Member 3-Like 1, Pseudogene 3
  • AFG3 ATPase Family Gene 3-Like 1, Pseudogene 3
  • AFG3 (ATPase Family Gene 3, Yeast)-Like 1 3
  • AFG3L1 3
  • AFG3 3

External Ids for AFG3L1P Gene

Previous HGNC Symbols for AFG3L1P Gene

  • AFG3
  • AFG3L1

Previous GeneCards Identifiers for AFG3L1P Gene

  • GC16P090039
  • GC16P090041

Summaries for AFG3L1P Gene

GeneCards Summary for AFG3L1P Gene

AFG3L1P (AFG3 Like Matrix AAA Peptidase Subunit 1, Pseudogene) is a Pseudogene. Diseases associated with AFG3L1P include Hereditary Spastic Paraplegia.

Additional gene information for AFG3L1P Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for AFG3L1P Gene

Genomics for AFG3L1P Gene

GeneHancer (GH) Regulatory Elements for AFG3L1P Gene

Promoters and enhancers for AFG3L1P Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around AFG3L1P on UCSC Golden Path with GeneCards custom track

Genomic Locations for AFG3L1P Gene

Genomic Locations for AFG3L1P Gene
chr16:89,972,580-90,002,161
(GRCh38/hg38)
Size:
29,582 bases
Orientation:
Plus strand
chr16:90,038,988-90,068,569
(GRCh37/hg19)
Size:
29,582 bases
Orientation:
Plus strand

Genomic View for AFG3L1P Gene

Genes around AFG3L1P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
AFG3L1P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for AFG3L1P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for AFG3L1P Gene

Proteins for AFG3L1P Gene

Post-translational modifications for AFG3L1P Gene

No Post-translational modifications

No data available for DME Specific Peptides for AFG3L1P Gene

Domains & Families for AFG3L1P Gene

Gene Families for AFG3L1P Gene

HGNC:
genes like me logo Genes that share domains with AFG3L1P: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for AFG3L1P Gene

Function for AFG3L1P Gene

Phenotypes From GWAS Catalog for AFG3L1P Gene

genes like me logo Genes that share phenotypes with AFG3L1P: view

Animal Model Products

  • Taconic Biosciences Mouse Models for AFG3L1P

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for AFG3L1P

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for AFG3L1P Gene

Localization for AFG3L1P Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for AFG3L1P Gene

Pathways & Interactions for AFG3L1P Gene

PathCards logo

SuperPathways for AFG3L1P Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for AFG3L1P Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for AFG3L1P Gene

Drugs & Compounds for AFG3L1P Gene

No Compound Related Data Available

Transcripts for AFG3L1P Gene

mRNA/cDNA for AFG3L1P Gene

2 REFSEQ mRNAs :
21 NCBI additional mRNA sequence :
17 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for AFG3L1P

Alternative Splicing Database (ASD) splice patterns (SP) for AFG3L1P Gene

No ASD Table

Relevant External Links for AFG3L1P Gene

GeneLoc Exon Structure for
AFG3L1P

Expression for AFG3L1P Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for AFG3L1P Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for AFG3L1P

SOURCE GeneReport for Unigene cluster for AFG3L1P Gene:

Hs.534773
genes like me logo Genes that share expression patterns with AFG3L1P: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for AFG3L1P Gene

Orthologs for AFG3L1P Gene

Evolution for AFG3L1P Gene

ENSEMBL:
Gene Tree for AFG3L1P (if available)
TreeFam:
Gene Tree for AFG3L1P (if available)

No data available for Orthologs for AFG3L1P Gene

Paralogs for AFG3L1P Gene

No data available for Paralogs for AFG3L1P Gene

Variants for AFG3L1P Gene

Structural Variations from Database of Genomic Variants (DGV) for AFG3L1P Gene

Variant ID Type Subtype PubMed ID
esv2136699 CNV deletion 18987734
esv2664835 CNV deletion 23128226
esv2762221 CNV gain+loss 21179565
esv3639603 CNV gain 21293372
esv3639604 CNV loss 21293372
esv3639605 CNV loss 21293372
esv3689 CNV loss 18987735
esv3892941 CNV gain 25118596
nsv103059 CNV insertion 16902084
nsv103116 CNV deletion 16902084
nsv1066499 CNV loss 25217958
nsv428331 CNV gain+loss 18775914
nsv457626 CNV loss 19166990
nsv471119 CNV loss 18288195
nsv471120 CNV gain 18288195
nsv477114 CNV novel sequence insertion 20440878
nsv479100 CNV novel sequence insertion 20440878
nsv482951 CNV loss 15286789
nsv573799 CNV gain 21841781
nsv573810 CNV loss 21841781
nsv573841 CNV loss 21841781
nsv573842 CNV loss 21841781
nsv952080 CNV deletion 24416366

Additional Variant Information for AFG3L1P Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
AFG3L1P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Additional dbSNP identifiers (rs#s) and Variation tolerance for AFG3L1P Gene

Disorders for AFG3L1P Gene

MalaCards: The human disease database

(1) MalaCards diseases for AFG3L1P Gene - From: GeneCards

Disorder Aliases PubMed IDs
hereditary spastic paraplegia
  • spastic paraplegia 3, autosomal dominant
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for AFG3L1P

genes like me logo Genes that share disorders with AFG3L1P: view

No data available for UniProtKB/Swiss-Prot and Genatlas for AFG3L1P Gene

Publications for AFG3L1P Gene

  1. Molecular and functional analyses of the human and mouse genes encoding AFG3L1, a mitochondrial metalloprotease homologous to the human spastic paraplegia protein. (PMID: 11549317) Kremmidiotis G … Callen DF (Genomics 2001) 2 3 23 54
  2. Chromosomal locations of three human nuclear genes (RPSM12, TUFM, and AFG3L1) specifying putative components of the mitochondrial gene expression apparatus. (PMID: 9545647) Shah ZH … Jacobs HT (Genomics 1998) 2 3 23 54
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T … Vidal M (Cell 2014) 3 54
  4. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) Oláh J … Ovádi J (The Journal of biological chemistry 2011) 3 54
  5. The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control of the cell cycle. (PMID: 21555518) Warnatz HJ … Yaspo ML (The Journal of biological chemistry 2011) 3 54

Products for AFG3L1P Gene

Sources for AFG3L1P Gene