This gene encodes a member of carboxypeptidase A protein family. The encoded protein may function as a transcriptional repressor and play a role in adipogenesis and smooth muscle cell differentiation. Studies in mice suggest that this gene functions in wound healing and abdominal wall development. Overexpression of this gene is associated with glioblastoma. [provided by RefSeq,... See more...

Aliases for AEBP1 Gene

Aliases for AEBP1 Gene

  • AE Binding Protein 1 2 3 5
  • Aortic Carboxypeptidase-Like Protein 2 3 4
  • ACLP 2 3 4
  • Adipocyte Enhancer-Binding Protein 1 3 4
  • AE-Binding Protein 1 2 4
  • Adipocyte Enhancer Binding Protein 1 2
  • AEBP1 5

External Ids for AEBP1 Gene

Previous GeneCards Identifiers for AEBP1 Gene

  • GC07P043790
  • GC07P043850
  • GC07P043884
  • GC07P043917
  • GC07P044110
  • GC07P044143
  • GC07P044029

Summaries for AEBP1 Gene

Entrez Gene Summary for AEBP1 Gene

  • This gene encodes a member of carboxypeptidase A protein family. The encoded protein may function as a transcriptional repressor and play a role in adipogenesis and smooth muscle cell differentiation. Studies in mice suggest that this gene functions in wound healing and abdominal wall development. Overexpression of this gene is associated with glioblastoma. [provided by RefSeq, May 2013]

CIViC Summary for AEBP1 Gene

GeneCards Summary for AEBP1 Gene

AEBP1 (AE Binding Protein 1) is a Protein Coding gene. Diseases associated with AEBP1 include Ehlers-Danlos Syndrome, Classic-Like, 2 and Gastroschisis. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity and calmodulin binding. An important paralog of this gene is CPXM2.

UniProtKB/Swiss-Prot Summary for AEBP1 Gene

  • [Isoform 1]: As a positive regulator of collagen fibrillogenesis, it is probably involved in the organization and remodeling of the extracellular matrix.
  • [Isoform 2]: May positively regulate MAP-kinase activity in adipocytes, leading to enhanced adipocyte proliferation and reduced adipocyte differentiation. May also positively regulate NF-kappa-B activity in macrophages by promoting the phosphorylation and subsequent degradation of I-kappa-B-alpha (NFKBIA), leading to enhanced macrophage inflammatory responsiveness. Can act as a transcriptional repressor.

Additional gene information for AEBP1 Gene

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for AEBP1 Gene

Genomics for AEBP1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for AEBP1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH07J044099 Promoter/Enhancer 2.3 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 612.5 -1.3 -1302 7.3 PRDM10 TFE3 ZIC2 PKNOX1 EZH2 GABPA PBX2 ZNF341 SCRT2 JUND AEBP1 POLM GCK RASA4CP RF00017-6148
GH07J043112 Promoter/Enhancer 1.8 EPDnew Ensembl ENCODE CraniofacialAtlas 14.7 -990.8 -990819 2.2 RNF2 TEAD4 PRDM10 ZIC2 POLR2A PATZ1 EZH2 ZNF600 ZNF341 KLF9 ENSG00000232006 HECW1 AEBP1 GLI3 ENSG00000228434 SPDYE1 POLM lnc-HECW1-1 STK17A
GH07J044200 Promoter/Enhancer 2 EPDnew Ensembl ENCODE CraniofacialAtlas 11.2 +97.4 97352 2.7 SP1 HNRNPL CREB1 CTCF ZNF629 SIX5 ZNF692 POLR2A BACH1 JUND YKT6 piR-41405-069 POLM DDX56 POLR2J4 SNORA5C TMED4 SNHG15 AEBP1 ENSG00000228434
GH07J044063 Promoter/Enhancer 1.4 EPDnew Ensembl ENCODE CraniofacialAtlas 11.2 -39.3 -39320 2.8 TEAD4 POLR2A PKNOX1 USF1 RBM22 SIN3A REST STAT5A YY1 RBPJ ENSG00000239775 PGAM2 RASA4CP POLM AEBP1 LINC00957 DBNL
GH07J044157 Promoter/Enhancer 1.2 EPDnew Ensembl dbSUPER 11.7 +54.1 54081 2.4 IKZF1 FOXA1 SP1 UBTF EGR1 CTCF NR2C2 NCOR1 TBP NR2F1 GCK POLD2 RNA5SP230 AEBP1 POLM ENSG00000239775 PGAM2 LOC105375257 LOC105375258 MYL7
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around AEBP1 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for AEBP1

Top Transcription factor binding sites by QIAGEN in the AEBP1 gene promoter:
  • AREB6
  • Olf-1
  • PPAR-gamma1
  • PPAR-gamma2
  • Sp1
  • SRF
  • SRF (504 AA)

Genomic Locations for AEBP1 Gene

Genomic Locations for AEBP1 Gene
chr7:44,104,320-44,114,564
(GRCh38/hg38)
Size:
10,245 bases
Orientation:
Plus strand
chr7:44,143,960-44,154,161
(GRCh37/hg19)
Size:
10,202 bases
Orientation:
Plus strand

Genomic View for AEBP1 Gene

Genes around AEBP1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
AEBP1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for AEBP1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for AEBP1 Gene

Proteins for AEBP1 Gene

  • Protein details for AEBP1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8IUX7-AEBP1_HUMAN
    Recommended name:
    Adipocyte enhancer-binding protein 1
    Protein Accession:
    Q8IUX7
    Secondary Accessions:
    • Q14113
    • Q59ER7
    • Q6ZSC7
    • Q7KZ79

    Protein attributes for AEBP1 Gene

    Size:
    1158 amino acids
    Molecular mass:
    130929 Da
    Quaternary structure:
    • Isoform 1: Interacts with different types of collagen, including collagens I, III, and V (PubMed:29606302). Isoform 2: Interacts with GNG5, NFKBIA, MAPK1, MAPK3 and PTEN. Interaction with MAPK1 may stimulate DNA-binding. May interact with calmodulin. Binds to DNA in vitro.
    SequenceCaution:
    • Sequence=BAD92981.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for AEBP1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for AEBP1 Gene

Post-translational modifications for AEBP1 Gene

  • Phosphorylated by MAPK1 in vitro.
  • Glycosylation at Asn528, Asn480, and Asn922
  • Ubiquitination at Lys753
  • Modification sites at PhosphoSitePlus
  • Glycosylation from GlyConnect
    • AEBP1_HUMAN (995)

No data available for DME Specific Peptides for AEBP1 Gene

Domains & Families for AEBP1 Gene

Gene Families for AEBP1 Gene

HGNC:
IUPHAR :
Human Protein Atlas (HPA):
  • Enzymes
  • Predicted intracellular proteins
  • Predicted secreted proteins

Protein Domains for AEBP1 Gene

InterPro:
Blocks:
  • Coagulation factor 5/8 type C domain (FA58C)
ProtoNet:

Suggested Antigen Peptide Sequences for AEBP1 Gene

GenScript: Design optimal peptide antigens:
  • Aortic carboxypeptidase-like protein (AEBP1_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q8IUX7

UniProtKB/Swiss-Prot:

AEBP1_HUMAN :
  • [Isoform 1]: The F5/8 type C domain binds to different types of collagen, including collagens I, III, and V.
  • Belongs to the peptidase M14 family.
Domain:
  • [Isoform 1]: The F5/8 type C domain binds to different types of collagen, including collagens I, III, and V.
Family:
  • Belongs to the peptidase M14 family.
genes like me logo Genes that share domains with AEBP1: view

Function for AEBP1 Gene

Molecular function for AEBP1 Gene

UniProtKB/Swiss-Prot Function:
[Isoform 1]: As a positive regulator of collagen fibrillogenesis, it is probably involved in the organization and remodeling of the extracellular matrix.
UniProtKB/Swiss-Prot Function:
[Isoform 2]: May positively regulate MAP-kinase activity in adipocytes, leading to enhanced adipocyte proliferation and reduced adipocyte differentiation. May also positively regulate NF-kappa-B activity in macrophages by promoting the phosphorylation and subsequent degradation of I-kappa-B-alpha (NFKBIA), leading to enhanced macrophage inflammatory responsiveness. Can act as a transcriptional repressor.

Phenotypes From GWAS Catalog for AEBP1 Gene

Gene Ontology (GO) - Molecular Function for AEBP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IDA 15654748
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific IMP 15654748
GO:0003677 DNA binding IEA --
GO:0003714 transcription corepressor activity IBA 21873635
GO:0004180 carboxypeptidase activity IEA --
genes like me logo Genes that share ontologies with AEBP1: view
genes like me logo Genes that share phenotypes with AEBP1: view

Human Phenotype Ontology for AEBP1 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for AEBP1 Gene

MGI Knock Outs for AEBP1:

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for AEBP1

No data available for Enzyme Numbers (IUBMB) , miRNA , Transcription Factor Targets and HOMER Transcription for AEBP1 Gene

Localization for AEBP1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for AEBP1 Gene

[Isoform 1]: Secreted.
[Isoform 2]: Cytoplasm. Nucleus.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for AEBP1 gene
Compartment Confidence
extracellular 4
nucleus 4
cytoskeleton 2
endoplasmic reticulum 2
golgi apparatus 2
plasma membrane 1
mitochondrion 1
cytosol 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Vesicles (3)
  • Cytosol (2)
  • Nucleoplasm (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for AEBP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region HDA 27068509
GO:0005615 extracellular space IBA 21873635
GO:0005634 nucleus IEA --
GO:0005737 cytoplasm IEA --
GO:0062023 colocalizes_with collagen-containing extracellular matrix HDA 20551380
genes like me logo Genes that share ontologies with AEBP1: view

Pathways & Interactions for AEBP1 Gene

PathCards logo

SuperPathways for AEBP1 Gene

No Data Available

Interacting Proteins for AEBP1 Gene

Gene Ontology (GO) - Biological Process for AEBP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000122 negative regulation of transcription by RNA polymerase II IMP 15654748
GO:0006355 regulation of transcription, DNA-templated IEA --
GO:0006508 proteolysis IEA --
GO:0006518 peptide metabolic process IBA 21873635
GO:0016485 protein processing IBA 21873635
genes like me logo Genes that share ontologies with AEBP1: view

No data available for Pathways by source and SIGNOR curated interactions for AEBP1 Gene

Drugs & Compounds for AEBP1 Gene

(1) Drugs for AEBP1 Gene - From: Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
genes like me logo Genes that share compounds with AEBP1: view

Transcripts for AEBP1 Gene

mRNA/cDNA for AEBP1 Gene

1 REFSEQ mRNAs :
9 NCBI additional mRNA sequence :
9 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for AEBP1

Alternative Splicing Database (ASD) splice patterns (SP) for AEBP1 Gene

ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8a · 8b · 8c ^ 9a · 9b ^ 10 ^ 11 ^ 12a · 12b · 12c · 12d · 12e ^ 13a · 13b · 13c ^ 14a ·
SP1: - - -
SP2: - - - -
SP3:
SP4:
SP5: - - - - - -
SP6: -
SP7: - - -
SP8: - - -
SP9: - - - - -
SP10:
SP11:
SP12: - - -
SP13: -
SP14:
SP15:
SP16: -
SP17:

ExUns: 14b ^ 15a · 15b · 15c ^ 16a · 16b · 16c ^ 17a · 17b · 17c ^ 18a · 18b ^ 19a · 19b · 19c ^ 20 ^ 21 ^ 22 ^ 23
SP1: - - -
SP2:
SP3: - -
SP4: - -
SP5:
SP6:
SP7:
SP8: - -
SP9:
SP10: - -
SP11:
SP12:
SP13:
SP14:
SP15:
SP16:
SP17:

Relevant External Links for AEBP1 Gene

GeneLoc Exon Structure for
AEBP1

Expression for AEBP1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for AEBP1 Gene

mRNA differential expression in normal tissues according to GTEx for AEBP1 Gene

This gene is overexpressed in Artery - Aorta (x8.7), Artery - Coronary (x6.6), and Artery - Tibial (x5.5).

Protein differential expression in normal tissues from HIPED for AEBP1 Gene

This gene is overexpressed in Amniocyte (26.8), Breast (9.1), and Prostate (7.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for AEBP1 Gene



Protein tissue co-expression partners for AEBP1 Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for AEBP1

SOURCE GeneReport for Unigene cluster for AEBP1 Gene:

Hs.439463

mRNA Expression by UniProt/SwissProt for AEBP1 Gene:

Q8IUX7-AEBP1_HUMAN
Tissue specificity: Expressed in osteoblast and visceral fat.

Evidence on tissue expression from TISSUES for AEBP1 Gene

  • Nervous system(4.8)
  • Muscle(4.6)
  • Liver(4.5)
  • Bone(4.2)
  • Heart(2.6)
  • Kidney(2.6)
  • Intestine(2.6)
  • Skin(2.4)
  • Lung(2.3)
  • Spleen(2.1)
  • Lymph node(2.1)
  • Gall bladder(2.1)
  • Pancreas(2)
genes like me logo Genes that share expression patterns with AEBP1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and Phenotype-based relationships between genes and organs from Gene ORGANizer for AEBP1 Gene

Orthologs for AEBP1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for AEBP1 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia AEBP1 30 31
  • 99.48 (n)
OneToOne
Dog
(Canis familiaris)
Mammalia AEBP1 30 31
  • 89.48 (n)
OneToOne
Cow
(Bos Taurus)
Mammalia AEBP1 30 31
  • 84.79 (n)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Aebp1 30
  • 83.41 (n)
Mouse
(Mus musculus)
Mammalia Aebp1 30 17 31
  • 83.36 (n)
OneToOne
Oppossum
(Monodelphis domestica)
Mammalia AEBP1 31
  • 78 (a)
OneToOne
Platypus
(Ornithorhynchus anatinus)
Mammalia AEBP1 31
  • 74 (a)
OneToOne
Chicken
(Gallus gallus)
Aves AEBP1 31
  • 74 (a)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia AEBP1 31
  • 65 (a)
OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia aebp1 30
  • 62.44 (n)
Zebrafish
(Danio rerio)
Actinopterygii aebp1 31
  • 49 (a)
OneToMany
AEBP1 (1 of 2) 31
  • 37 (a)
OneToMany
Rainbow Trout
(Oncorhynchus mykiss)
Actinopterygii Omy.2504 30
Sea Squirt
(Ciona savignyi)
Ascidiacea -- 31
  • 38 (a)
OneToMany
Species where no ortholog for AEBP1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)

Evolution for AEBP1 Gene

ENSEMBL:
Gene Tree for AEBP1 (if available)
TreeFam:
Gene Tree for AEBP1 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for AEBP1: view image

Paralogs for AEBP1 Gene

Paralogs for AEBP1 Gene

(4) SIMAP similar genes for AEBP1 Gene using alignment to 7 proteins:

  • AEBP1_HUMAN
  • C9JLQ8_HUMAN
  • H7C0W8_HUMAN
  • H7C1J5_HUMAN
  • H7C391_HUMAN
  • H7C3D7_HUMAN
  • H7C4B5_HUMAN
genes like me logo Genes that share paralogs with AEBP1: view

Variants for AEBP1 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for AEBP1 Gene

SNP ID Clinical significance and condition Chr 07 pos Variation AA Info Type
709651 Likely Benign: not provided 44,113,875(+) G/A MISSENSE_VARIANT
709786 Benign: not provided 44,110,905(+) C/G NON_CODING_TRANSCRIPT_VARIANT,INTRON_VARIANT
716743 Likely Benign: not provided 44,108,039(+) C/T MISSENSE_VARIANT
736843 Benign: not provided 44,106,852(+) C/G MISSENSE_VARIANT
776219 Benign: not provided 44,110,276(+) A/T MISSENSE_VARIANT

Additional dbSNP identifiers (rs#s) for AEBP1 Gene

Structural Variations from Database of Genomic Variants (DGV) for AEBP1 Gene

Variant ID Type Subtype PubMed ID
dgv11297n54 CNV loss 21841781
nsv428165 CNV gain 18775914
nsv470210 CNV loss 18288195
nsv606746 CNV loss 21841781
nsv606747 CNV gain 21841781
nsv606749 CNV loss 21841781
nsv8082 CNV gain 18304495
nsv830983 CNV loss 17160897

Variation tolerance for AEBP1 Gene

Residual Variation Intolerance Score: 22.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 11.50; 92.91% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for AEBP1 Gene

Human Gene Mutation Database (HGMD)
AEBP1
SNPedia medical, phenotypic, and genealogical associations of SNPs for
AEBP1

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for AEBP1 Gene

Disorders for AEBP1 Gene

MalaCards: The human disease database

(6) MalaCards diseases for AEBP1 Gene - From: OMIM, ClinVar, GTR, Orphanet, DISEASES, and GeneCards

Disorder Aliases PubMed IDs
ehlers-danlos syndrome, classic-like, 2
  • edscll2
gastroschisis
  • congenital fissure of the abdominal cavity
ehlers-danlos syndrome, classic-like
  • edscll
ehlers-danlos syndrome
  • cutis hyperelastica
larsen-like syndrome b3gat3 type
  • larsen-like syndrome, b3gat3 type
- elite association - COSMIC cancer census association via MalaCards
Search AEBP1 in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

AEBP1_HUMAN
  • Ehlers-Danlos syndrome, classic-like, 2 (EDSCLL2) [MIM:618000]: A variant form of Ehlers-Danlos syndrome, a connective tissue disorder. EDSCLL2 patients show severe joint and skin laxity, osteoporosis affecting the hips and spine, osteoarthritis, soft redundant skin that can be acrogeria-like, delayed wound healing with abnormal atrophic scarring, and shoulder, hip, knee, and ankle dislocations. Additional variable features include gastrointestinal and genitourinary manifestations (bowel rupture, gut dysmotility, cryptorchidism, and hernias), vascular complications (mitral valve prolapse and aortic root dilation), and skeletal anomalies. EDSCLL2 inheritance is autosomal recessive. {ECO:0000269 PubMed:27023906, ECO:0000269 PubMed:29606302}. Note=The disease is caused by mutations affecting the gene represented in this entry.
genes like me logo Genes that share disorders with AEBP1: view

No data available for Genatlas for AEBP1 Gene

Publications for AEBP1 Gene

  1. A cDNA cloning of human AEBP1 from primary cultured osteoblasts and its expression in a differentiating osteoblastic cell line. (PMID: 8920928) Ohno I … Okubo K (Biochemical and biophysical research communications 1996) 2 3 4 23
  2. Aortic carboxypeptidase-like protein, a novel protein with discoidin and carboxypeptidase-like domains, is up-regulated during vascular smooth muscle cell differentiation. (PMID: 9624159) Layne MD … Lee ME (The Journal of biological chemistry 1998) 3 4 23
  3. Bi-allelic Alterations in AEBP1 Lead to Defective Collagen Assembly and Connective Tissue Structure Resulting in a Variant of Ehlers-Danlos Syndrome. (PMID: 29606302) Blackburn PR … Atwal PS (American journal of human genetics 2018) 3 4
  4. PPARgamma1 and LXRalpha face a new regulator of macrophage cholesterol homeostasis and inflammatory responsiveness, AEBP1. (PMID: 20419060) Majdalawieh A … Ro HS (Nuclear receptor signaling 2010) 3 23
  5. Regulation of IkappaBalpha function and NF-kappaB signaling: AEBP1 is a novel proinflammatory mediator in macrophages. (PMID: 20396415) Majdalawieh A … Ro HS (Mediators of inflammation 2010) 3 23

Products for AEBP1 Gene

Sources for AEBP1 Gene