Aliases for ADSS2 Gene
External Ids for ADSS2 Gene
Previous HGNC Symbols for ADSS2 Gene
This gene encodes the enzyme adenylosuccinate synthetase which catalyzes the first committed step in the conversion of inosine monophosphate to adenosine monophosphate. A pseudogene of this gene is found on chromosome 17.[provided by RefSeq, Nov 2010]
GeneCards Summary for ADSS2 Gene
ADSS2 (Adenylosuccinate Synthase 2) is a Protein Coding gene. Diseases associated with ADSS2 include Eczema Herpeticum and Deafness, Autosomal Dominant 69. Among its related pathways are Nucleotide Metabolism and purine nucleotides de novo biosynthesis. An important paralog of this gene is ADSS1.
UniProtKB/Swiss-Prot Summary for ADSS2 Gene
Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.