Aliases for ADSS Gene
External Ids for ADSS Gene
Previous GeneCards Identifiers for ADSS Gene
This gene encodes the enzyme adenylosuccinate synthetase which catalyzes the first committed step in the conversion of inosine monophosphate to adenosine monophosphate. A pseudogene of this gene is found on chromosome 17.[provided by RefSeq, Nov 2010]
GeneCards Summary for ADSS Gene
ADSS (Adenylosuccinate Synthase) is a Protein Coding gene. Among its related pathways are Pyrimidine metabolism (KEGG) and Metabolism. Gene Ontology (GO) annotations related to this gene include GTP binding and phosphate ion binding. An important paralog of this gene is ADSSL1.
UniProtKB/Swiss-Prot for ADSS Gene
Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.