Aliases for ADPRM Gene
External Ids for ADPRM Gene
Previous HGNC Symbols for ADPRM Gene
GeneCards Summary for ADPRM Gene
ADPRM (ADP-Ribose/CDP-Alcohol Diphosphatase, Manganese Dependent) is a Protein Coding gene. Diseases associated with ADPRM include Leigh Syndrome. Among its related pathways are Pyrimidine metabolism (KEGG) and Metabolism. Gene Ontology (GO) annotations related to this gene include hydrolase activity and CDP-glycerol diphosphatase activity.
UniProtKB/Swiss-Prot for ADPRM Gene
Hydrolyzes ADP-ribose, IDP-ribose, CDP-glycerol, CDP-choline and CDP-ethanolamine, but not other non-reducing ADP-sugars or CDP-glucose. May be involved in immune cell signaling as suggested by the second-messenger role of ADP-ribose, which activates TRPM2 as a mediator of oxidative/nitrosative stress (By similarity).