Aliases for ADPRH Gene
External Ids for ADPRH Gene
Previous GeneCards Identifiers for ADPRH Gene
The enzyme encoded by this gene catalyzes removal of mono-ADP-ribose from arginine residues of proteins in the ADP-ribosylation cycle. Unlike the rat and mouse enzymes that require DTT for maximal activity, the human enzyme is DTT-independent. Alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, May 2014]
GeneCards Summary for ADPRH Gene
ADPRH (ADP-Ribosylarginine Hydrolase) is a Protein Coding gene. Diseases associated with ADPRH include Tyrosinemia and Mucolipidosis Ii Alpha/Beta. Gene Ontology (GO) annotations related to this gene include magnesium ion binding and ADP-ribosylarginine hydrolase activity. An important paralog of this gene is ADPRHL1.
UniProtKB/Swiss-Prot Summary for ADPRH Gene
Specifically acts as a arginine mono-ADP-ribosylhydrolase by mediating the removal of mono-ADP-ribose attached to arginine residues on proteins.