Free for academic non-profit institutions. Other users need a Commercial license

Aliases for ADORA2A-AS1 Gene

Subcategory (RNA class) for ADORA2A-AS1 Gene

non-coding RNA

Quality Score for this RNA gene is


Aliases for ADORA2A-AS1 Gene

  • ADORA2A Antisense RNA 1 2 3 4 5
  • C22orf45 3 4
  • Putative Uncharacterized Protein ADORA2A-AS1 4
  • Chromosome 22 Open Reading Frame 45 2
  • ADORA2A Antisense Gene Protein 1 4

External Ids for ADORA2A-AS1 Gene

Previous HGNC Symbols for ADORA2A-AS1 Gene

  • C22orf45

Previous GeneCards Identifiers for ADORA2A-AS1 Gene

  • GC22M024826
  • GC22M024955
  • GC22M025178
  • GC22M024563
  • GC22M024667
  • GC22M026654
  • GC22M025051
  • GC22M025468
  • GC22M025651
  • GC22M025841
  • GC22M026024
  • GC22M026206
  • GC22M026386
  • GC22M026560

Summaries for ADORA2A-AS1 Gene

GeneCards Summary for ADORA2A-AS1 Gene

ADORA2A-AS1 (ADORA2A Antisense RNA 1) is an RNA Gene, and is affiliated with the non-coding RNA class.

Additional gene information for ADORA2A-AS1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ADORA2A-AS1 Gene

Genomics for ADORA2A-AS1 Gene

GeneHancer (GH) Regulatory Elements for ADORA2A-AS1 Gene

Promoters and enhancers for ADORA2A-AS1 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH22J024493 Promoter/Enhancer 1.7 EPDnew Ensembl ENCODE 611.1 +0.6 595 1.9 ZNF652 SP1 RXRA FOXA2 EZH2 MGA JUND USF1 ATF3 YY1 UPB1 ADORA2A-AS1
GH22J024423 Promoter/Enhancer 2.4 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 13.9 +63.9 63920 15.5 SP1 NKRF ZNF687 CTCF RELA KLF14 CREM MLLT1 RAD21 ZBED1 ADORA2A POM121L9P SPECC1L ZNF70 ENSG00000232545 UPB1 ADORA2A-AS1 SMARCB1 SNRPD3 ENSG00000272578
GH22J024459 Enhancer 1.2 Ensembl ENCODE dbSUPER 27.2 +31.4 31373 9.4 ZNF121 SP1 ZNF548 PRDM1 EGR1 ZNF639 SMARCA4 RXRA DPF2 IKZF1 UPB1 ADORA2A-AS1 SPECC1L POM121L9P ADORA2A ENSG00000228923 ZNF70 SNRPD3 BCRP3 GC22P024449
GH22J024548 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 11.4 -58.4 -58388 8.9 ZNF652 SP1 ZFX ELF3 MNT SIX5 NKRF POLR2A ZNF121 CEBPG GGT1 SNRPD3 GUCD1 ENSG00000272973 SGSM1 UPB1 ADORA2A SLC2A11 ENSG00000228923 SMARCB1
GH22J024449 Enhancer 1 Ensembl ENCODE dbSUPER 26.6 +45.2 45169 3 ZNF148 POLR2A USF1 BCOR RCOR1 ADNP ZMYM3 ZNF362 CBFA2T3 SPECC1L UPB1 ADORA2A-AS1 ADORA2A ENSG00000228923 GC22P024449 GC22P024451
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ADORA2A-AS1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for ADORA2A-AS1 Gene

Genomic Locations for ADORA2A-AS1 Gene
65,869 bases
Minus strand
65,865 bases
Minus strand

Genomic View for ADORA2A-AS1 Gene

Genes around ADORA2A-AS1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ADORA2A-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ADORA2A-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ADORA2A-AS1 Gene

Proteins for ADORA2A-AS1 Gene

  • Protein details for ADORA2A-AS1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Putative uncharacterized protein ADORA2A-AS1
    Protein Accession:

    Protein attributes for ADORA2A-AS1 Gene

    159 amino acids
    Molecular mass:
    17238 Da
    Quaternary structure:
    No Data Available
    • This protein has no orthologs in other species and appears to be the product of a protein-coding gene which has arisen since divergence from chimp.

neXtProt entry for ADORA2A-AS1 Gene

Post-translational modifications for ADORA2A-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for ADORA2A-AS1 Gene

Domains & Families for ADORA2A-AS1 Gene

Protein Domains for ADORA2A-AS1 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ADORA2A-AS1: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for ADORA2A-AS1 Gene

Function for ADORA2A-AS1 Gene

Phenotypes From GWAS Catalog for ADORA2A-AS1 Gene

genes like me logo Genes that share phenotypes with ADORA2A-AS1: view

Animal Model Products

CRISPR Products

miRNA for ADORA2A-AS1 Gene

miRTarBase miRNAs that target ADORA2A-AS1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ADORA2A-AS1 Gene

Localization for ADORA2A-AS1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for ADORA2A-AS1 Gene

Pathways & Interactions for ADORA2A-AS1 Gene

PathCards logo

SuperPathways for ADORA2A-AS1 Gene

No Data Available

Interacting Proteins for ADORA2A-AS1 Gene

Gene Ontology (GO) - Biological Process for ADORA2A-AS1 Gene


No data available for Pathways by source and SIGNOR curated interactions for ADORA2A-AS1 Gene

Drugs & Compounds for ADORA2A-AS1 Gene

(1) Drugs for ADORA2A-AS1 Gene - From: PharmGKB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Methotrexate Approved Pharma Folate antagonist,inhibits DFHR 1736
genes like me logo Genes that share compounds with ADORA2A-AS1: view

Transcripts for ADORA2A-AS1 Gene

mRNA/cDNA for ADORA2A-AS1 Gene

(1) REFSEQ mRNAs :
(5) Additional mRNA sequences :
(4) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(2) RNA Central transcripts :

Unigene Clusters for ADORA2A-AS1 Gene

ADORA2A antisense RNA 1:
Representative Sequences:

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for ADORA2A-AS1 Gene

No ASD Table

Relevant External Links for ADORA2A-AS1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ADORA2A-AS1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ADORA2A-AS1 Gene

mRNA differential expression in normal tissues according to GTEx for ADORA2A-AS1 Gene

This gene is overexpressed in Liver (x11.3), Testis (x6.5), and Brain - Putamen (basal ganglia) (x5.6).

SOURCE GeneReport for Unigene cluster for ADORA2A-AS1 Gene:

genes like me logo Genes that share expression patterns with ADORA2A-AS1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ADORA2A-AS1 Gene

Orthologs for ADORA2A-AS1 Gene

Evolution for ADORA2A-AS1 Gene

Gene Tree for ADORA2A-AS1 (if available)
Gene Tree for ADORA2A-AS1 (if available)

No data available for Orthologs for ADORA2A-AS1 Gene

Paralogs for ADORA2A-AS1 Gene

No data available for Paralogs for ADORA2A-AS1 Gene

Variants for ADORA2A-AS1 Gene

Sequence variations from dbSNP and Humsavar for ADORA2A-AS1 Gene

SNP ID Clin Chr 22 pos Variation AA Info Type
rs116629687 uncertain-significance, Deficiency of beta-ureidopropionase 24,495,341(-) C/T upstream_transcript_variant
rs200677387 uncertain-significance, Deficiency of beta-ureidopropionase 24,495,397(-) C/A/G/T upstream_transcript_variant
rs2070474 not-provided, benign, not provided, Deficiency of beta-ureidopropionase 24,495,324(-) C/G/T upstream_transcript_variant
rs2070475 not-provided, benign, not provided, Deficiency of beta-ureidopropionase 24,495,387(-) A/G/T upstream_transcript_variant
rs2298383 drug-response, caffeine response - Toxicity/ADR 24,429,543(-) C/A/T genic_downstream_transcript_variant, non_coding_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for ADORA2A-AS1 Gene

Variant ID Type Subtype PubMed ID
dgv4528n100 CNV gain 25217958
dgv8039n54 CNV gain 21841781
esv2668824 CNV deletion 23128226
esv2678940 CNV deletion 23128226
esv2724041 CNV deletion 23290073
esv2724068 CNV deletion 23290073
esv3557989 CNV deletion 23714750
esv3568311 CNV loss 25503493
esv3575443 CNV gain 25503493
esv3647434 CNV loss 21293372
esv3647435 CNV loss 21293372
esv3893463 CNV gain 25118596
nsv1055830 CNV gain 25217958
nsv1057819 CNV gain 25217958
nsv1110863 OTHER inversion 24896259
nsv526567 CNV gain 19592680
nsv588744 CNV gain 21841781
nsv7350 OTHER inversion 18451855
nsv834160 CNV gain 17160897
nsv953062 CNV duplication 24416366
nsv9884 CNV gain+loss 18304495

Additional Variant Information for ADORA2A-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for ADORA2A-AS1 Gene

Disorders for ADORA2A-AS1 Gene

Additional Disease Information for ADORA2A-AS1

No disorders were found for ADORA2A-AS1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ADORA2A-AS1 Gene

Publications for ADORA2A-AS1 Gene

  1. Recent de novo origin of human protein-coding genes. (PMID: 19726446) Knowles DG … McLysaght A (Genome research 2009) 2 3 4 58
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  3. Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris. (PMID: 24927181) Navarini AA … Barker JN (Nature communications 2014) 3 58
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 58
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58

Products for ADORA2A-AS1 Gene

  • Biorbyt antibodies for ADORA2A-AS1

Sources for ADORA2A-AS1 Gene

Loading form....