Aliases for ADORA2A-AS1 Gene

Subcategory (RNA class) for ADORA2A-AS1 Gene

lncRNA

Number of RNA Genes sources:

3 / 17

Aliases for ADORA2A-AS1 Gene

  • ADORA2A Antisense RNA 1 2 3 4 5
  • ADORA2A-AS1 2 5 165
  • C22orf45 3 4
  • Putative Uncharacterized Protein ADORA2A-AS1 4
  • Chromosome 22 Open Reading Frame 45 2
  • ADORA2A Antisense Gene Protein 1 4
  • NONHSAG033519.2 91
  • HSALNG0134494 164
  • HSALNG0134495 164
  • HSALNG0134501 164
  • FLJ34651 2

External Ids for ADORA2A-AS1 Gene

Previous HGNC Symbols for ADORA2A-AS1 Gene

  • C22orf45

Previous GeneCards Identifiers for ADORA2A-AS1 Gene

  • GC22M024826
  • GC22M024955
  • GC22M025178
  • GC22M024563
  • GC22M024667
  • GC22M026654
  • GC22M026852
  • GC22M026988
  • GC22M027500
  • GC22M025051
  • GC22M025468
  • GC22M025651
  • GC22M025841
  • GC22M026024
  • GC22M026206
  • GC22M026386
  • GC22M026560

Summaries for ADORA2A-AS1 Gene

GeneCards Summary for ADORA2A-AS1 Gene

ADORA2A-AS1 (ADORA2A Antisense RNA 1) is an RNA Gene, and is affiliated with the lncRNA class.

Additional gene information for ADORA2A-AS1 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ADORA2A-AS1 Gene

Genomics for ADORA2A-AS1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for ADORA2A-AS1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ADORA2A-AS1 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for ADORA2A-AS1 Gene

Genomic Locations for ADORA2A-AS1 Gene
chr22:24,424,409-24,495,074
(GRCh38/hg38)
Size:
70,666 bases
Orientation:
Minus strand
chr22:24,825,178-24,891,042
(GRCh37/hg19)
Size:
65,865 bases
Orientation:
Minus strand

Genomic View for ADORA2A-AS1 Gene

Genes around ADORA2A-AS1 on UCSC Golden Path with GeneCards custom track
ADORA2A-AS1 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
ADORA2A-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ADORA2A-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ADORA2A-AS1 Gene

Proteins for ADORA2A-AS1 Gene

  • Protein details for ADORA2A-AS1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P86434-AAS1_HUMAN
    Recommended name:
    Putative uncharacterized protein ADORA2A-AS1
    Protein Accession:
    P86434

    Protein attributes for ADORA2A-AS1 Gene

    Size:
    159 amino acids
    Molecular mass:
    17238 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • This protein has no orthologs in other species and appears to be the product of a protein-coding gene which has arisen since divergence from chimp.

neXtProt entry for ADORA2A-AS1 Gene

Post-translational modifications for ADORA2A-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for ADORA2A-AS1 Gene

Domains & Families for ADORA2A-AS1 Gene

Gene Families for ADORA2A-AS1 Gene

Protein Domains for ADORA2A-AS1 Gene

ProtoNet:
genes like me logo Genes that share domains with ADORA2A-AS1: view

No data available for Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for ADORA2A-AS1 Gene

Function for ADORA2A-AS1 Gene

Phenotypes From GWAS Catalog for ADORA2A-AS1 Gene

genes like me logo Genes that share phenotypes with ADORA2A-AS1: view

Animal Model Products

CRISPR Products

miRNA for ADORA2A-AS1 Gene

miRTarBase miRNAs that target ADORA2A-AS1

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ADORA2A-AS1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ADORA2A-AS1 Gene

Localization for ADORA2A-AS1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for ADORA2A-AS1 Gene

Pathways & Interactions for ADORA2A-AS1 Gene

PathCards logo

SuperPathways for ADORA2A-AS1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ADORA2A-AS1 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for ADORA2A-AS1 Gene

Drugs & Compounds for ADORA2A-AS1 Gene

(1) Drugs for ADORA2A-AS1 Gene - From: PharmGKB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Methotrexate Approved Pharma Folate antagonist,inhibits DFHR 1825
genes like me logo Genes that share compounds with ADORA2A-AS1: view

Transcripts for ADORA2A-AS1 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for ADORA2A-AS1 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS0000499CE3_9606 lncRNA 2027 3

Ensembl: ENST00000427813 (view in UCSC) ,

LNCipedia: ADORA2A-AS1:1,

NONCODE: NONHSAT084348.2,

URS0000ABD8B1_9606 lncRNA 2831 2

RefSeq: NR_028484,

LNCipedia: ADORA2A-AS1:19,

URS00007735F0_9606 lncRNA 2557 2

Ensembl: ENST00000326341 (view in UCSC) ,

LNCipedia: ADORA2A-AS1:5,

URS00008E39D5_9606 lncRNA 2026 2

HGNC: 37122,

RefSeq: NR_028483,

URS0000E88CD2_9606 lncRNA 1367 1

Ensembl: ENST00000650766 (view in UCSC) ,

ADORA2A-AS1 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for ADORA2A-AS1 Gene

1 REFSEQ mRNAs :
5 NCBI additional mRNA sequence :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ADORA2A-AS1

Alternative Splicing Database (ASD) splice patterns (SP) for ADORA2A-AS1 Gene

No ASD Table

Relevant External Links for ADORA2A-AS1 Gene

GeneLoc Exon Structure for
ADORA2A-AS1

Expression for ADORA2A-AS1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ADORA2A-AS1 Gene

mRNA differential expression in normal tissues according to GTEx for ADORA2A-AS1 Gene

This gene is overexpressed in Liver (x11.3), Testis (x6.5), and Brain - Putamen (basal ganglia) (x5.6).

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ADORA2A-AS1

SOURCE GeneReport for Unigene cluster for ADORA2A-AS1 Gene:

Hs.632761
genes like me logo Genes that share expression patterns with ADORA2A-AS1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ADORA2A-AS1 Gene

Orthologs for ADORA2A-AS1 Gene

Evolution for ADORA2A-AS1 Gene

ENSEMBL:
Gene Tree for ADORA2A-AS1 (if available)
TreeFam:
Gene Tree for ADORA2A-AS1 (if available)

No data available for Orthologs for ADORA2A-AS1 Gene

Paralogs for ADORA2A-AS1 Gene

No data available for Paralogs for ADORA2A-AS1 Gene

Variants for ADORA2A-AS1 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ADORA2A-AS1 Gene

SNP ID Clinical significance and condition Chr 22 pos Variation AA Info Type
758935 Likely Benign: not provided 24,433,745(-) G/A INTRON_VARIANT
769157 Benign: not provided 24,440,689(-) G/A MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT
769158 Benign: not provided 24,440,961(-) C/A NON_CODING_TRANSCRIPT_VARIANT,SYNONYMOUS_VARIANT
774536 Benign: not provided 24,441,135(-) C/T NON_CODING_TRANSCRIPT_VARIANT,SYNONYMOUS_VARIANT
780634 Benign: not provided 24,441,294(-) C/T NON_CODING_TRANSCRIPT_VARIANT,SYNONYMOUS_VARIANT

Additional dbSNP identifiers (rs#s) for ADORA2A-AS1 Gene

Structural Variations from Database of Genomic Variants (DGV) for ADORA2A-AS1 Gene

Variant ID Type Subtype PubMed ID
dgv4528n100 CNV gain 25217958
dgv8039n54 CNV gain 21841781
esv2668824 CNV deletion 23128226
esv2678940 CNV deletion 23128226
esv2724041 CNV deletion 23290073
esv2724068 CNV deletion 23290073
esv3557989 CNV deletion 23714750
esv3568311 CNV loss 25503493
esv3575443 CNV gain 25503493
esv3647434 CNV loss 21293372
esv3647435 CNV loss 21293372
esv3893463 CNV gain 25118596
nsv1055830 CNV gain 25217958
nsv1057819 CNV gain 25217958
nsv1110863 OTHER inversion 24896259
nsv526567 CNV gain 19592680
nsv588744 CNV gain 21841781
nsv7350 OTHER inversion 18451855
nsv834160 CNV gain 17160897
nsv953062 CNV duplication 24416366
nsv9884 CNV gain+loss 18304495

Additional Variant Information for ADORA2A-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ADORA2A-AS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for ADORA2A-AS1 Gene

Disorders for ADORA2A-AS1 Gene

No disorders were found for ADORA2A-AS1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ADORA2A-AS1 Gene

Publications for ADORA2A-AS1 Gene

  1. Recent de novo origin of human protein-coding genes. (PMID: 19726446) Knowles DG … McLysaght A (Genome research 2009) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
  3. Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris. (PMID: 24927181) Navarini AA … Barker JN (Nature communications 2014) 3
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3

Products for ADORA2A-AS1 Gene

Sources for ADORA2A-AS1 Gene