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Aliases for ADM5 Gene
Aliases for ADM5 Gene
External Ids for ADM5 Gene
- HGNC: 27293
- Entrez Gene: 199800
- Ensembl: ENSG00000224420
- UniProtKB: C9JUS6
Previous HGNC Symbols for ADM5 Gene
- C19orf76
Previous GeneCards Identifiers for ADM5 Gene
- GC19P050197
- GC19P050198
- GC19P050205
Summaries for ADM5 Gene
GeneCards Summary for ADM5 Gene
ADM5 (Adrenomedullin 5 (Putative)) is a Protein Coding gene. Diseases associated with ADM5 include Breast Adenomyoepithelioma and Breast Myoepithelial Neoplasm.
UniProtKB/Swiss-Prot Summary for ADM5 Gene
-
Probable non-functional remnant of adrenomedullin-5.
Additional gene information for ADM5 Gene
- HGNC(27293)
- Entrez Gene(199800)
- Ensembl(ENSG00000224420)
- UniProtKB(C9JUS6)
- Open Targets Platform(ENSG00000224420)
- Search for ADM5 at DataMed
- Search for ADM5 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ADM5 Gene
Genomics for ADM5 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for ADM5 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around ADM5 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ADM5
Genomic Locations for ADM5 Gene
Genomic Locations for ADM5 Gene
- chr19:49,688,664-49,690,990
- (GRCh38/hg38)
- Size:
- 2,327 bases
- Orientation:
- Plus strand
- chr19:50,191,921-50,194,247
- (GRCh37/hg19)
- Size:
- 2,327 bases
- Orientation:
- Plus strand
Genomic View for ADM5 Gene
Genes around ADM5 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19q13.33 by HGNC
- 19q13.33 by Entrez Gene
- 19q13.33 by Ensembl
ADM5 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ADM5 Gene
Proteins for ADM5 Gene
-
Protein details for ADM5 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- C9JUS6-ADM5_HUMAN
- Recommended name:
- Putative adrenomedullin-5-like protein
- Protein Accession:
- C9JUS6
Protein attributes for ADM5 Gene
- Size:
- 153 amino acids
- Molecular mass:
- 16532 Da
- Quaternary structure:
- No Data Available
Post-translational modifications for ADM5 Gene
No Post-translational modifications
Other Protein References for ADM5 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- antibodies-online: Search results for available ADM5 related products ranked by validation data
Protein Products
-
OriGene Purified Proteins for ADM5
- Search Origene for MassSpec and Protein Over-expression Lysates for ADM5
- Origene Custom Protein Services for ADM5
- antibodies-online: Search results for available ADM5 related products ranked by validation data
No data available for DME Specific Peptides for ADM5 Gene
Domains & Families for ADM5 Gene
Gene Families for ADM5 Gene
- Human Protein Atlas (HPA):
-
- Predicted secreted proteins
Protein Domains for ADM5 Gene
- ProtoNet:
Suggested Antigen Peptide Sequences for ADM5 Gene
- GenScript: Design optimal peptide antigens:
-
- Putative adrenomedullin-5-like protein (ADM5_HUMAN)
Graphical View of Domain Structure for InterPro Entry
C9JUS6- Family:
-
- Belongs to the adrenomedullin family.
Function for ADM5 Gene
Molecular function for ADM5 Gene
- UniProtKB/Swiss-Prot Function:
- Probable non-functional remnant of adrenomedullin-5.
Phenotypes From GWAS Catalog for ADM5 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003674 | molecular_function | ND | -- |
Phenotypes for ADM5 Gene
- GenomeRNAi human phenotypes for ADM5:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for ADM5 - Select products 50% OFF >
- * ADM5 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for ADM5
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ADM5
-
Santa Cruz Biotechnology (SCBT) CRISPR for ADM5
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ADM5
- Browse OriGene Inhibitory RNA Products For ADM5
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ADM5
Clone Products
- Applied Biological Materials (abm): Clones for ADM5 - Select products 50% OFF >
- * ADM5 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for ADM5
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ADM5
Cell Line Products
-
Horizon Cell Lines for ADM5
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ADM5 Gene
Localization for ADM5 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ADM5 Gene
- Secreted.
| Compartment | Confidence |
|---|---|
| extracellular | 4 |
| plasma membrane | 2 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| nucleus | 1 |
| endoplasmic reticulum | 1 |
| cytosol | 1 |
| golgi apparatus | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005575 | cellular_component | ND | -- |
| GO:0005576 | extracellular region | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for ADM5 Gene
Pathways & Interactions for ADM5 Gene
Interacting Proteins for ADM5 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0008150 | biological_process | ND | -- |
No data available for Pathways by source and SIGNOR curated interactions for ADM5 Gene
Transcripts for ADM5 Gene
mRNA/cDNA for ADM5 Gene
- 1 REFSEQ mRNAs :
- 5 NCBI additional mRNA sequence :
- 1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000420022 1718 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for ADM5 - Select products 50% OFF >
- * ADM5 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for ADM5
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ADM5
-
Santa Cruz Biotechnology (SCBT) CRISPR for ADM5
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ADM5
- Browse OriGene Inhibitory RNA Products For ADM5
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ADM5
Clone Products
- Applied Biological Materials (abm): Clones for ADM5 - Select products 50% OFF >
- * ADM5 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for ADM5
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ADM5
Relevant External Links for ADM5 Gene
- GeneLoc Exon Structure for
- ADM5
Expression for ADM5 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ADM5
SOURCE GeneReport for Unigene cluster for ADM5 Gene:
Hs.311193Primer Products
-
OriGene qPCR primer pairs for ADM5
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ADM5 Gene
Orthologs for ADM5 Gene
This gene was present in the common ancestor of mammals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | ADM5 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | ADM5 30 |
|
||
| Dog (Canis familiaris) |
Mammalia | ADM5 30 31 |
|
OneToOne |
- Species where no ortholog for ADM5 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Lizard (Anolis carolinensis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Mouse (Mus musculus)
- Oppossum (Monodelphis domestica)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rainbow Trout (Oncorhynchus mykiss)
- Rat (Rattus norvegicus)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
- Zebrafish (Danio rerio)
Evolution for ADM5 Gene
- ENSEMBL:
- Gene Tree for ADM5 (if available)
- TreeFam:
- Gene Tree for ADM5 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for ADM5: view image
Paralogs for ADM5 Gene
No data available for Paralogs for ADM5 Gene
Variants for ADM5 Gene
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv1160655 | CNV | deletion | 26073780 |
| nsv469715 | CNV | gain+loss | 16826518 |
| nsv470150 | CNV | gain | 18288195 |
| nsv7308 | OTHER | inversion | 18451855 |
| nsv817854 | CNV | gain | 17921354 |
| nsv833864 | CNV | gain | 17160897 |
| nsv833865 | CNV | gain+loss | 17160897 |
| nsv953600 | CNV | deletion | 24416366 |
| nsv9739 | CNV | gain+loss | 18304495 |
Gene Damage Index Score:
1.34;
26.51% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for ADM5 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- ADM5
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ADM5 Gene
Disorders for ADM5 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| breast adenomyoepithelioma |
|
|
| breast myoepithelial neoplasm |
|
|
| toxic pneumonitis |
|
|
| phlebotomus fever |
|
|
Search ADM5 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for ADM5
No data available for UniProtKB/Swiss-Prot and Genatlas for ADM5 Gene
Publications for ADM5 Gene
- Central and peripheral cardiovascular actions of adrenomedullin 5, a novel member of the calcitonin gene-related peptide family, in mammals. (PMID: 18434369) Takei Y … Ueta Y (The Journal of endocrinology 2008) 2 3 4
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4
- The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J … Lucas SM (Nature 2004) 4
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3
ExternalLinks
Products for ADM5 Gene
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for ADM5
- Search Origene for MassSpec and Protein Over-expression Lysates for ADM5
- Origene Custom Protein Services for ADM5
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ADM5
- Browse OriGene Inhibitory RNA Products For ADM5
- OriGene qPCR primer pairs for ADM5
- OriGene CRISPR knockouts for ADM5
- OriGene ORF clones in human for ADM5
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For ADM5
- Sino Biological Human cDNA Clone for ADM5
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- VectorBuilder Custom and pre-made DNA vectors for ADM5 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for ADM5 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for ADM5 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for ADM5 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for ADM5
- antibodies-online: Search results for available ADM5 related products ranked by validation data
- antibodies-online: Search results for available ADM5 related products ranked by validation data
- antibodies-online: Search results for available ADM5 related products ranked by validation data
- Horizon Cell Lines for ADM5
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ADM5
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ADM5
- Search GeneCopoeia for miRNA 3'UTR Target clone products for ADM5
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ADM5
Sources for ADM5 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB