Aliases for ADIRF Gene
External Ids for ADIRF Gene
Previous HGNC Symbols for ADIRF Gene
Previous GeneCards Identifiers for ADIRF Gene
APM2 gene is exclusively expressed in adipose tissue. Its function is currently unknown. [provided by RefSeq, Jul 2008]
GeneCards Summary for ADIRF Gene
ADIRF (Adipogenesis Regulatory Factor) is a Protein Coding gene. Diseases associated with ADIRF include Vagina Leiomyosarcoma and Dystonia 9. Among its related pathways are Developmental Biology and Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha).
UniProtKB/Swiss-Prot Summary for ADIRF Gene
Plays a role in fat cell development; promotes adipogenic differentiation and stimulates transcription initiation of master adipogenesis factors like PPARG and CEBPA at early stages of preadipocyte differentiation. Its overexpression confers resistance to the anticancer chemotherapeutic drug cisplatin.