Free for academic non-profit institutions. Other users need a Commercial license
ADIG/SMAF1 is an adipocyte-specific protein that plays a role in adipocyte differentiation (Kim et al., 2005 [PubMed 15567149]; Hong et al., 2005 [PubMed 16132694]).[supplied by OMIM, Mar 2008]
ADIG (Adipogenin) is a Protein Coding gene.
GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
---|---|---|---|---|---|---|---|---|---|---|
GH20J038581 | Promoter/Enhancer | 1 | EPDnew Ensembl | 600.7 | -1.1 | -1094 | 4.2 | HNRNPL ZNF629 POLR2A ZNF600 SCRT2 TCF7 CREB1 RBM22 ZFHX2 ZNF511 | ADIG HSALNG0129995 SNHG17 ENSG00000224635 SNORA71A SNORA71B ARHGAP40 RPS3P2 RALGAPB | |
GH20J038604 | Enhancer | 1.1 | Ensembl ENCODE | 11.5 | +24.1 | 24053 | 1.5 | GATAD2A ATF7 TFE3 SOX13 NFKBIZ RCOR2 TARDBP FOXA1 RBFOX2 RXRB | ADIG SNHG17 ARHGAP40 ENSG00000213959 SLC32A1 | |
GH20J038617 | Enhancer | 0.4 | Ensembl | 11.3 | +36.2 | 36240 | 1 | KDM1A ESR1 TBP | ENSG00000213959 LOC391247 ADIG ARHGAP40 lnc-KIAA1755-9 SLC32A1 | |
GH20J038603 | Enhancer | 0.3 | Ensembl | 11.5 | +22.9 | 22906 | 0.6 | ZNF341 GMEB1 | ADIG ARHGAP40 ENSG00000213959 SLC32A1 | |
GH20J038610 | Enhancer | 0.3 | Ensembl | 11.5 | +28.9 | 28906 | 0.6 | RFX1 BMI1 | ARHGAP40 ADIG ENSG00000213959 SLC32A1 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005634 | nucleus | ISS | 15567149 |
GO:0005737 | cytoplasm | ISS | 15567149 |
GO:0005811 | lipid droplet | IEA,IBA | 21873635 |
GO:0016020 | membrane | IEA | -- |
GO:0016021 | integral component of membrane | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0007283 | spermatogenesis | IEA | -- |
GO:0045444 | fat cell differentiation | IEA | -- |
GO:0045600 | positive regulation of fat cell differentiation | ISS | 15567149 |
GO:0050872 | white fat cell differentiation | ISS | 15567149 |
GO:0050873 | brown fat cell differentiation | ISS | 15567149 |
This gene was present in the common ancestor of mammals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | ADIG 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | ADIG 30 |
|
||
Cow (Bos Taurus) |
Mammalia | ADIG 30 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Adig 30 |
|
||
Mouse (Mus musculus) |
Mammalia | Adig 31 |
|
OneToOne |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
nsv1058457 | CNV | loss | 25217958 |
nsv3372 | CNV | insertion | 18451855 |
No disorders were found for ADIG Gene.