ADH1C Gene (Protein Coding)

Alcohol Dehydrogenase 1C (Class I), Gamma Polypeptide

GC04M099336
GIFtS:
43
This gene encodes class I alcohol dehydrogenase, gamma subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class I alcohol dehydrogenase, consisting of several homo- and heterodimers of alpha, ... See more...

Aliases for ADH1C Gene

Aliases for ADH1C Gene

  • Alcohol Dehydrogenase 1C (Class I), Gamma Polypeptide 2 3 5
  • Alcohol Dehydrogenase 1C 3 4
  • EC 1.1.1.1 4 52
  • ADH3 3 4
  • Alcohol Dehydrogenase 3 (Class I), Gamma Polypeptide 3
  • Alcohol Dehydrogenase Subunit Gamma 4
  • ADH, Gamma Subunit 3
  • Aldehyde Reductase 3
  • EC 1.1.1 52

External Ids for ADH1C Gene

Previous HGNC Symbols for ADH1C Gene

  • ADH3

Previous GeneCards Identifiers for ADH1C Gene

  • GC04M100504
  • GC04M100386
  • GC04M100452
  • GC04M100457
  • GC04M100614
  • GC04M100257
  • GC04M095995

Summaries for ADH1C Gene

Entrez Gene Summary for ADH1C Gene

  • This gene encodes class I alcohol dehydrogenase, gamma subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class I alcohol dehydrogenase, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation to acetaldehyde, thus playing a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. An association between ADH1C polymorphism and alcohol dependence has not been established. [provided by RefSeq, Sep 2019]

GeneCards Summary for ADH1C Gene

ADH1C (Alcohol Dehydrogenase 1C (Class I), Gamma Polypeptide) is a Protein Coding gene. Diseases associated with ADH1C include Alcohol Dependence and Parkinson Disease, Late-Onset. Among its related pathways are Drug metabolism - cytochrome P450 and Signaling by Retinoic Acid. Gene Ontology (GO) annotations related to this gene include oxidoreductase activity and alcohol dehydrogenase (NAD) activity. An important paralog of this gene is ADH1B.

Gene Wiki entry for ADH1C Gene

PharmGKB "VIP" Summary for ADH1C Gene

Additional gene information for ADH1C Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Rfam classification and piRNA Summary for ADH1C Gene

Genomics for ADH1C Gene

GeneHancer (GH) Regulatory Elements for ADH1C Gene

Promoters and enhancers for ADH1C Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH04J099352 Promoter/Enhancer 1.1 EPDnew Ensembl ENCODE 509.9 -0.2 -161 1.2 RAD21 RXRA MAX TAF1 REST SP1 ADH1C ADH1B lnc-ADH1A-2 ADH1A ADH5 piR-59928-097
GH04J099351 Enhancer 0.4 FANTOM5 516.7 +1.5 1496 0.4 FOXA2 FOXA1 ADH1C ADH1B lnc-ADH1A-2 ADH6 ADH1A ADH4 piR-45726-029
GH04J099382 Enhancer 1.3 FANTOM5 Ensembl ENCODE dbSUPER 11.5 -31.1 -31050 3.1 FOXA2 NR2F2 ZBTB33 NFE2 JUND FOXP1 MAFK MNT ZGPAT BHLHE40 ADH1C ADH1A MTTP ADH5 piR-57133-461 LOC102723576 lnc-ADH7-1
GH04J099381 Enhancer 0.4 FANTOM5 27.4 -28.1 -28101 0.2 SP1 YY1 ADH1A ADH4 ADH1C ADH1B ADH6 ENSG00000246090 piR-57133-461 LOC102723576
GH04J099394 Enhancer 0.9 Ensembl ENCODE dbSUPER 11.6 -42.4 -42393 2.1 REST ZNF316 MAFF MAFK NFE2 MAFG RXRA NFE2L2 HNF4A BACH1 ADH1C ENSG00000246090 ADH1A RNU7-149P MTTP LOC102723576 lnc-ADH7-1 piR-57133-461
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ADH1C on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ADH1C

Top Transcription factor binding sites by QIAGEN in the ADH1C gene promoter:
  • CUTL1
  • FOXC1
  • Oct-B1
  • oct-B2
  • oct-B3
  • POU2F1
  • POU2F1a
  • POU2F2
  • POU2F2 (Oct-2.1)

Genomic Locations for ADH1C Gene

Genomic Locations for ADH1C Gene
chr4:99,336,492-99,353,045
(GRCh38/hg38)
Size:
16,554 bases
Orientation:
Minus strand
chr4:100,257,649-100,274,184
(GRCh37/hg19)
Size:
16,536 bases
Orientation:
Minus strand

Genomic View for ADH1C Gene

Genes around ADH1C on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ADH1C Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ADH1C Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for ADH1C Gene

Proteins for ADH1C Gene

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  • Protein details for ADH1C Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P00326-ADH1G_HUMAN
    Recommended name:
    Alcohol dehydrogenase 1C
    Protein Accession:
    P00326
    Secondary Accessions:
    • Q4PJ18
    • Q5WRV0
    • Q6LBW4
    • Q6NWV0
    • Q6NZA7

    Protein attributes for ADH1C Gene

    Size:
    375 amino acids
    Molecular mass:
    39868 Da
    Cofactor:
    Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
    Quaternary structure:
    • Dimer of identical or non-identical chains of three types; alpha, beta and gamma.
    Miscellaneous:
    • There are 7 different ADH's isozymes in human: three belongs to class-I: alpha, beta, and gamma, one to class-II: pi, one to class-III: chi, one to class-IV: ADH7 and one to class-V: ADH6.

    Three dimensional structures from OCA and Proteopedia for ADH1C Gene

neXtProt entry for ADH1C Gene

Protein Expression for ADH1C Gene

See protein expression from ProteomicsDB, MOPED, PaxDb, and MaxQB

Selected DME Specific Peptides for ADH1C Gene

P00326:
  • CLIGCGF
  • EVAPPKA
  • FSQYTVV
  • KINEGFDLL
  • ESVGEGVT
  • VPKLVAD
  • ILGHEAAG
  • LLRSGKSIRT
  • EEVEVAPP
  • PQCGKCR
  • SVIVGVPP
  • EVRIKMV
  • GRTWKGA
  • GHEAAGIVES
  • NKDKFAKAK
  • CAVFGLGGVGLS
  • CINPQDY
  • GKVIKCKAA
  • DFMAKKF
  • PVILGHE
  • GCGFSTGYG
  • AKVTPGS
  • CKNPESN
  • KPIQEVL
  • EMTDGGV
  • VMGCKAAGA
  • PGDKVIPLF
  • DINKDKF
  • GATECINP
  • TAGKVIKC
  • PLEKVCL
  • GIVESVG

Post-translational modifications for ADH1C Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ADH1C Gene

ENSEMBL proteins:
REFSEQ proteins:

Domains & Families for ADH1C Gene

Gene Families for ADH1C Gene

HGNC:
Human Protein Atlas (HPA):
  • Enzymes
  • FDA approved drug targets
  • Plasma proteins
  • Predicted intracellular proteins

Protein Domains for ADH1C Gene

Blocks:
  • Zinc-containing alcohol dehydrogenase
  • Alcohol dehydrogenase GroES-like
InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for ADH1C Gene

GenScript: Design optimal peptide antigens:
  • Alcohol dehydrogenase subunit gamma (ADH1G_HUMAN)
  • Alcohol dehydrogenase 3 (Q71V49_HUMAN)

Graphical View of Domain Structure for InterPro Entry

P00326

UniProtKB/Swiss-Prot:

ADH1G_HUMAN :
  • Belongs to the zinc-containing alcohol dehydrogenase family.
Family:
  • Belongs to the zinc-containing alcohol dehydrogenase family.
genes like me logo Genes that share domains with ADH1C: view

Function for ADH1C Gene

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Molecular function for ADH1C Gene

UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH; Xref=Rhea:RHEA:10736, ChEBI:CHEBI:15378, ChEBI:CHEBI:15734, ChEBI:CHEBI:17478, ChEBI:CHEBI:57540, ChEBI:CHEBI:57945; EC=1.1.1.1;.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=a secondary alcohol + NAD(+) = a ketone + H(+) + NADH; Xref=Rhea:RHEA:10740, ChEBI:CHEBI:15378, ChEBI:CHEBI:17087, ChEBI:CHEBI:35681, ChEBI:CHEBI:57540, ChEBI:CHEBI:57945; EC=1.1.1.1;.

Enzyme Numbers (IUBMB) for ADH1C Gene

Phenotypes From GWAS Catalog for ADH1C Gene

Gene Ontology (GO) - Molecular Function for ADH1C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004022 alcohol dehydrogenase (NAD) activity IDA 6391957
GO:0004024 alcohol dehydrogenase activity, zinc-dependent IBA 21873635
GO:0004745 retinol dehydrogenase activity IBA 21873635
GO:0008270 zinc ion binding IBA,IEA 21873635
GO:0016491 oxidoreductase activity IEA --
genes like me logo Genes that share ontologies with ADH1C: view
genes like me logo Genes that share phenotypes with ADH1C: view

Human Phenotype Ontology for ADH1C Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for ADH1C Gene

MGI Knock Outs for ADH1C:

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ADH1C

No data available for miRNA , Transcription Factor Targets and HOMER Transcription for ADH1C Gene

Localization for ADH1C Gene

Subcellular locations from UniProtKB/Swiss-Prot for ADH1C Gene

Cytoplasm.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ADH1C gene
Compartment Confidence
plasma membrane 4
nucleus 4
cytosol 4
extracellular 2
mitochondrion 2
peroxisome 2
cytoskeleton 1
endoplasmic reticulum 1
lysosome 1
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (3)
  • Plasma membrane (3)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for ADH1C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005654 nucleoplasm IDA --
GO:0005737 cytoplasm IEA --
GO:0005829 cytosol TAS --
GO:0005886 plasma membrane IDA --
genes like me logo Genes that share ontologies with ADH1C: view

Pathways & Interactions for ADH1C Gene

genes like me logo Genes that share pathways with ADH1C: view

Gene Ontology (GO) - Biological Process for ADH1C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006069 ethanol oxidation TAS --
GO:0042572 retinol metabolic process IBA 21873635
GO:0042573 retinoic acid metabolic process IBA 21873635
GO:0055114 oxidation-reduction process IEA --
genes like me logo Genes that share ontologies with ADH1C: view

No data available for SIGNOR curated interactions for ADH1C Gene

Drugs & Compounds for ADH1C Gene

Products:

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(33) Drugs for ADH1C Gene - From: DrugBank, PharmGKB, DGIdb, HMDB, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Fomepizole Approved, Vet_approved Pharma Target, inhibitor 4
Ethanol Approved Pharma Enzyme, substrate 3220
cholic acid Approved Pharma Full agonist, Agonist, Target 0
NADH Approved Nutra Target 0
Vitamin A Approved, Vet_approved Nutra 658

(19) Additional Compounds for ADH1C Gene - From: HMDB and Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
1-Piperidinecarboxaldehyde
  • 1-Formyl-piperidine
  • 1-Formylpiperidine
  • 1-Piperidinecarbaldehyde
  • Formylpiperidine
  • FPI
 2591-86-8
2,2,2-Trichloroethanol
  • 2,2,2-trichloro-1-Ethanol
  • Trichloroethanol
  • (Hydroxymethyl)trichloromethane
  • 2, 2,2-Trichloroethanol
  • 2,2,2-trichloro-Ethanol
 115-20-8
2-Phenyl-1,3-propanediol monocarbamate
3,4-Dihydroxymandelaldehyde
  • 3,4-Dihydroxymandelic aldehyde
  • 3,4-Dihydroxyphenylglycolaldehyde
  • 3,4-Dihydroxyphenylglycolic aldehyde
  • alpha,3,4-Trihydroxybenzeneacetaldehyde
  • alpha,3,4-Trihydroxyphenylacetaldehyde
 13023-73-9
3,4-Dihydroxyphenylglycol
  • (3,4-Dihydroxyphenyl)ethylene glycol
  • 1-(3,4-Dihydroxyphenyl)-1,2-ethanediol
  • 2-Hydroxy-2-(3,4-dihydroxy)phenylethanol
  • 3,4-Dihydroxyphenethyl glycol
  • 3,4-Dihydroxyphenylethyl glycol
 28822-73-3
genes like me logo Genes that share compounds with ADH1C: view

Transcripts for ADH1C Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

mRNA/cDNA for ADH1C Gene

1 REFSEQ mRNAs :
15 NCBI additional mRNA sequence :
4 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ADH1C

Alternative Splicing Database (ASD) splice patterns (SP) for ADH1C Gene

No ASD Table

Relevant External Links for ADH1C Gene

GeneLoc Exon Structure for
ADH1C

Expression for ADH1C Gene

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  1. Primer
  2. Gene Expression Assay

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ADH1C Gene

mRNA expression in normal human tissues for ADH1C Gene
mRNA expression by BioGPS for ADH1C GenemRNA expression by GTEx for ADH1C Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for ADH1C Gene

This gene is overexpressed in Liver (x21.9), Colon - Transverse (x10.0), and Stomach (x5.4).

Protein differential expression in normal tissues from HIPED for ADH1C Gene

This gene is overexpressed in Liver, secretome (18.6), Gallbladder (9.5), Liver (8.5), and Stomach (7.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ADH1C Gene



Protein tissue co-expression partners for ADH1C Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ADH1C

SOURCE GeneReport for Unigene cluster for ADH1C Gene:

Hs.654537
genes like me logo Genes that share expression patterns with ADH1C: view

No data available for mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ADH1C Gene

Orthologs for ADH1C Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for ADH1C Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
 Mammalia ADH1C 30
  • 99.38 (n)
dog
(Canis familiaris)
 Mammalia -- 31
  • 86 (a)
 OneToMany
LOC100856533 30
  • 85.96 (n)
cow
(Bos Taurus)
 Mammalia ADH1C 30
  • 85.51 (n)
-- 31
  • 74 (a)
 OneToMany
mouse
(Mus musculus)
 Mammalia Adh1 17 31 30
  • 82.22 (n)
rat
(Rattus norvegicus)
 Mammalia Adh1 30
  • 81.16 (n)
platypus
(Ornithorhynchus anatinus)
 Mammalia -- 31
  • 76 (a)
 OneToMany
oppossum
(Monodelphis domestica)
 Mammalia -- 31
  • 70 (a)
 OneToMany
chicken
(Gallus gallus)
 Aves -- 31
  • 71 (a)
 OneToMany
ADH1C 30
  • 70.4 (n)
lizard
(Anolis carolinensis)
 Reptilia -- 31
  • 74 (a)
 ManyToMany
-- 31
  • 72 (a)
 ManyToMany
-- 31
  • 68 (a)
 ManyToMany
-- 31
  • 68 (a)
 ManyToMany
-- 31
  • 67 (a)
 ManyToMany
-- 31
  • 66 (a)
 ManyToMany
-- 31
  • 66 (a)
 ManyToMany
tropical clawed frog
(Silurana tropicalis)
 Amphibia adh1c 30
  • 66.31 (n)
zebrafish
(Danio rerio)
 Actinopterygii zgc:63568 31
  • 56 (a)
 ManyToMany
zgc:77938 31
  • 56 (a)
 ManyToMany
adh8a 31
  • 54 (a)
 ManyToMany
adh8b 31
  • 51 (a)
 ManyToMany
fruit fly
(Drosophila melanogaster)
 Insecta Fdh 31
  • 52 (a)
 OneToMany
worm
(Caenorhabditis elegans)
 Secernentea H24K24.3 31
  • 50 (a)
 ManyToMany
Y50D4C.2 31
  • 32 (a)
 ManyToMany
baker's yeast
(Saccharomyces cerevisiae)
 Saccharomycetes SFA1 31
  • 45 (a)
 OneToMany
rice
(Oryza sativa)
 Liliopsida Os.12591 30
corn
(Zea mays)
 Liliopsida Zm.2859 30
sea squirt
(Ciona savignyi)
 Ascidiacea CSA.1497 31
  • 54 (a)
 OneToMany
Species where no ortholog for ADH1C was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for ADH1C Gene

ENSEMBL:
Gene Tree for ADH1C (if available)
TreeFam:
Gene Tree for ADH1C (if available)
Aminode:
Evolutionary constrained regions (ECRs) for ADH1C: view image

Paralogs for ADH1C Gene

Paralogs for ADH1C Gene

(6) SIMAP similar genes for ADH1C Gene using alignment to 1 proteins:

  • ADH1G_HUMAN
genes like me logo Genes that share paralogs with ADH1C: view

Variants for ADH1C Gene

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Polymorphic Variants from UniProtKB/Swiss-Prot for ADH1C Gene

ADH1G_HUMAN-P00326
Two main alleles are known, ADH3*1 or gamma-1 has Arg-272/Ile-350 while ADH3*2 or gamma-2 has Gln-272/Val-350. ADH3*1 is associated with a fast rate of ethanol oxidation and ADH3*2 with a slow rate.

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ADH1C Gene

SNP ID Clinical significance and condition Chr 04 pos Variation AA Info Type
709733 Benign: not provided 99,347,122(-) C/T MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT
716191 Benign: not provided 99,345,000(-) G/A NON_CODING_TRANSCRIPT_VARIANT,SYNONYMOUS_VARIANT
730985 Likely Benign: not provided 99,345,006(-) G/A NON_CODING_TRANSCRIPT_VARIANT,SYNONYMOUS_VARIANT
776589 Benign: not provided 99,344,907(-) G/A NON_CODING_TRANSCRIPT_VARIANT,SYNONYMOUS_VARIANT
778860 Benign: not provided 99,339,626(-) G/T MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT

Additional dbSNP identifiers (rs#s) for ADH1C Gene

Structural Variations from Database of Genomic Variants (DGV) for ADH1C Gene

Variant ID Type Subtype PubMed ID
dgv5345n100 CNV gain 25217958
esv2659036 CNV deletion 23128226
nsv1002809 CNV gain 25217958
nsv293592 CNV deletion 16902084
nsv528518 CNV loss 19592680
nsv966301 CNV duplication 23825009
nsv980234 CNV duplication 23825009

Additional Variant Information for ADH1C Gene

Human Gene Mutation Database (HGMD)
ADH1C
SNPedia medical, phenotypic, and genealogical associations of SNPs for
ADH1C

SNP Genotyping and Copy Number Assay Products

No data available for Variation tolerance for ADH1C Gene

Disorders for ADH1C Gene

MalaCards: The human disease database

(20) MalaCards diseases for ADH1C Gene - From: OMIM, ClinVar, GTR, DISEASES, Novoseek, and GeneCards

- elite association - COSMIC cancer census association via MalaCards
Search ADH1C in MalaCards View complete list of genes associated with diseases

Additional Disease Information for ADH1C

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with ADH1C: view

No data available for UniProtKB/Swiss-Prot and Genatlas for ADH1C Gene

Publications for ADH1C Gene

  1. Genetic polymorphism of alcohol-metabolizing enzyme and alcohol dependence in Polish men. (PMID: 20401433) Cichoz-Lach H … Lis E (Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2010) 3 23 41 54
  2. CYP2A13, ADH1B, and ADH1C gene polymorphisms and pancreatic cancer risk. (PMID: 19812523) Mohelnikova-Duchonova B … Soucek P (Pancreas 2010) 3 23 41 54
  3. Effects of polymorphisms in untranslated regions of the class I alcohol dehydrogenase (ADH) genes on alcohol metabolism in Japanese subjects and transcriptional activity in HepG2 cells. (PMID: 19618839) Nishimura FT … Saijoh K (Nihon Arukoru Yakubutsu Igakkai zasshi = Japanese journal of alcohol studies & drug dependence 2009) 3 26 41 54
  4. Genetic variation of alcohol dehydrogenase type 1C (ADH1C), alcohol consumption, and metabolic cardiovascular risk factors: results from the IMMIDIET study. (PMID: 19447389) Latella MC … European Collaborative Group of the IMMIDIET Project (Atherosclerosis 2009) 3 23 41 54
  5. Alcohol and colorectal cancer: the role of alcohol dehydrogenase 1C polymorphism. (PMID: 19120062) Homann N … Seitz HK (Alcoholism, clinical and experimental research 2009) 3 23 41 54

ExternalLinks

View latest publications for ADH1C gene in Mastermind

Products for ADH1C Gene

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Sources for ADH1C Gene