ADGRL2 Gene (Protein Coding)

Adhesion G Protein-Coupled Receptor L2

GC01P081306
GIFtS:
38
This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors. The encoded protein participates in the regulation of exocytosis. The proprotein is thought to be further cleaved within a cysteine-rich G-protein-coupled receptor proteolysis site into two chains that are non-covalently bound at the cell membrane. Alternative splicing results in multiple tr... See more...

Aliases for ADGRL2 Gene

Aliases for ADGRL2 Gene

  • Adhesion G Protein-Coupled Receptor L2 2 3 4 5
  • LEC1 2 3 4
  • Calcium-Independent Alpha-Latrotoxin Receptor 2 3 4
  • Latrophilin Homolog 1 3 4
  • Latrophilin-2 3 4
  • Lectomedin-1 3 4
  • KIAA0786 2 4
  • LPHH1 3 4
  • LPHN2 3 4
  • Latrophilin 1 2
  • Latrophilin 2 2
  • ADGRL2 5
  • CIRL-2 4
  • CIRL2 3
  • CL2 3

External Ids for ADGRL2 Gene

Previous HGNC Symbols for ADGRL2 Gene

  • LPHH1
  • LPHN2

Summaries for ADGRL2 Gene

Entrez Gene Summary for ADGRL2 Gene

  • This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors. The encoded protein participates in the regulation of exocytosis. The proprotein is thought to be further cleaved within a cysteine-rich G-protein-coupled receptor proteolysis site into two chains that are non-covalently bound at the cell membrane. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

GeneCards Summary for ADGRL2 Gene

ADGRL2 (Adhesion G Protein-Coupled Receptor L2) is a Protein Coding gene. Diseases associated with ADGRL2 include Rhombencephalosynapsis and Robinow Syndrome, Autosomal Recessive 1. Among its related pathways are GPCRs, Other and GPCRs, Class B Secretin-like. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and carbohydrate binding. An important paralog of this gene is ADGRL1.

UniProtKB/Swiss-Prot Summary for ADGRL2 Gene

  • Calcium-independent receptor of low affinity for alpha-latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis.

Gene Wiki entry for ADGRL2 Gene

Additional gene information for ADGRL2 Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ADGRL2 Gene

Genomics for ADGRL2 Gene

GeneHancer (GH) Regulatory Elements Pubs

Download GeneHancer 2017 data
Promoters and enhancers for ADGRL2 Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH01J081799 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 257.3 +496.1 496055 6.9 ZBTB10 FEZF1 CEBPA ETS1 ZNF217 CTCF ZEB1 ZIC2 ZNF610 ZNF513 ADGRL2 HSALNG0004717 HSALNG0004718 RF01045-007
GH01J081305 Promoter/Enhancer 1.7 EPDnew Ensembl ENCODE CraniofacialAtlas 256.6 +1.1 1052 3.7 CTCF RAD21 PRDM6 REST ZNF512B GATA2 PRDM4 ZNF792 TRIM28 L3MBTL2 ADGRL2 lnc-ADGRL2-4 RF00994-027
GH01J081698 Promoter/Enhancer 1.1 EPDnew Ensembl ENCODE dbSUPER 250 +393.8 393797 2.2 MAFK BACH1 EP300 JUND ADGRL2 ST13P20 LN871055 piR-39138-002 lnc-ADGRL2-4
GH01J081253 Enhancer 0.9 Ensembl ENCODE dbSUPER 10.9 -52.0 -52003 2.2 CTCF ZNF189 RAD21 ZNF143 NANOG POLR2A USF2 USF1 HSALNG0004706 ADGRL2 RN7SKP247
GH01J081978 Enhancer 1 Ensembl ENCODE dbSUPER 7.4 +671.4 671396 5 SIN3A FOXA2 RXRA RARA PRDM6 CREM FOXP1 SOX5 JUND HNF4A HSALNG0004720 ADGRL2 NONHSAG001916.2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around ADGRL2 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ADGRL2

Genomic Locations for ADGRL2 Gene

Latest Assembly
chr1:81,306,104-81,993,932
(GRCh38/hg38)
Size:
687,829 bases
Orientation:
Plus strand

Previous Assembly
chr1:81,771,877-82,459,616
(GRCh37/hg19 by Entrez Gene)
Size:
687,740 bases
Orientation:
Plus strand

chr1:81,771,845-82,458,120
(GRCh37/hg19 by Ensembl)
Size:
686,276 bases
Orientation:
Plus strand

Genomic View for ADGRL2 Gene

Genes around ADGRL2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ADGRL2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ADGRL2 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for ADGRL2 Gene

Proteins for ADGRL2 Gene

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  • Protein details for ADGRL2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O95490-AGRL2_HUMAN
    Recommended name:
    Adhesion G protein-coupled receptor L2
    Protein Accession:
    O95490
    Secondary Accessions:
    • A5XEI2
    • B1ALT8
    • B1ALT9
    • B1ALU0
    • B1ALU2
    • B1ALU4
    • B1ALU5
    • B1ALU6
    • O94882
    • Q5VX76
    • Q9UKY5
    • Q9UKY6

    Protein attributes for ADGRL2 Gene

    Size:
    1459 amino acids
    Molecular mass:
    163349 Da
    Quaternary structure:
    • Forms a heterodimer, consisting of a large extracellular region non-covalently linked to a seven-transmembrane moiety.

    Alternative splice isoforms for ADGRL2 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ADGRL2 Gene

Protein Expression for ADGRL2 Gene

See protein expression from ProteomicsDB, MOPED, PaxDb, and MaxQB

Post-translational modifications for ADGRL2 Gene

  • Proteolytically cleaved into 2 subunits, an extracellular subunit and a seven-transmembrane subunit.
  • Glycosylation at Asn99, Asn331, Asn520, Asn629, Asn731, Asn744, Asn787, Asn792, and Asn813
  • Modification sites at PhosphoSitePlus
  • Glycosylation from GlyConnect
    • AGRL2_HUMAN (994)

Other Protein References for ADGRL2 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibodies for research

  • Abcam antibodies for ADGRL2

No data available for DME Specific Peptides for ADGRL2 Gene

Domains & Families for ADGRL2 Gene

Gene Families for ADGRL2 Gene

HGNC:
Human Protein Atlas (HPA):
  • G-protein coupled receptors
  • Predicted membrane proteins

Protein Domains for ADGRL2 Gene

InterPro:
Blocks:
  • G-protein coupled receptors family 2 (secretin-like)
  • Olfactomedin-like
  • GPS domain
  • D-galactoside/L-rhamnose binding SUEL lectin domain
  • Latrophilin receptor signature
  • Protein prenyltransferase, alpha subunit
ProtoNet:

Suggested Antigen Peptide Sequences for ADGRL2 Gene

GenScript: Design optimal peptide antigens:
  • Latrophilin 2 (A5XEI2_HUMAN)
  • Latrophilin 2 (B1ALU6_HUMAN)
  • Lectomedin-1 (LPHN2_HUMAN)
  • Latrophilin-2 (Q9UJ48_HUMAN)
  • Latrophilin-2 (Q9UJ49_HUMAN)

Graphical View of Domain Structure for InterPro Entry

O95490

UniProtKB/Swiss-Prot:

AGRL2_HUMAN :
  • Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
Family:
  • Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
genes like me logo Genes that share domains with ADGRL2: view

Function for ADGRL2 Gene

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  6. Cell Lines for research

Molecular function for ADGRL2 Gene

UniProtKB/Swiss-Prot Function:
Calcium-independent receptor of low affinity for alpha-latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis.

Phenotypes From GWAS Catalog for ADGRL2 Gene

Gene Ontology (GO) - Molecular Function for ADGRL2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004888 transmembrane signaling receptor activity IEA --
GO:0004930 G protein-coupled receptor activity TAS,IBA 21873635
GO:0016524 latrotoxin receptor activity NAS 10030676
GO:0030246 carbohydrate binding IEA --
genes like me logo Genes that share ontologies with ADGRL2: view
genes like me logo Genes that share phenotypes with ADGRL2: view

Animal Models for ADGRL2 Gene

MGI Knock Outs for ADGRL2:

Animal Models for research

  • Taconic Biosciences Mouse Models for ADGRL2

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ADGRL2

Clone products for research

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for ADGRL2 Gene

Localization for ADGRL2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ADGRL2 Gene

Membrane. Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ADGRL2 gene
Compartment Confidence
plasma membrane 4
extracellular 2
endoplasmic reticulum 2
golgi apparatus 2
cytoskeleton 1
mitochondrion 1
nucleus 1
endosome 1
cytosol 1
lysosome 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cell Junctions (2)
  • Plasma membrane (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for ADGRL2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IEA --
GO:0005887 integral component of plasma membrane IBA 21873635
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane TAS,NAS 10030676
GO:0030424 axon IEA --
genes like me logo Genes that share ontologies with ADGRL2: view

Pathways & Interactions for ADGRL2 Gene

PathCards logo

SuperPathways for ADGRL2 Gene

genes like me logo Genes that share pathways with ADGRL2: view

Pathways by source for ADGRL2 Gene

2 BioSystems pathways for ADGRL2 Gene

Gene Ontology (GO) - Biological Process for ADGRL2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IEA --
GO:0007166 cell surface receptor signaling pathway IEA --
GO:0007186 G protein-coupled receptor signaling pathway TAS,NAS 10030676
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway IBA 21873635
GO:0007420 brain development IBA 21873635
genes like me logo Genes that share ontologies with ADGRL2: view

No data available for SIGNOR curated interactions for ADGRL2 Gene

Drugs & Compounds for ADGRL2 Gene

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(3) Drugs for ADGRL2 Gene - From: HMDB and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Calcium Nutra 6876

(1) Additional Compounds for ADGRL2 Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with ADGRL2: view

Transcripts for ADGRL2 Gene

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mRNA/cDNA for ADGRL2 Gene

21 REFSEQ mRNAs :
14 NCBI additional mRNA sequence :
41 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ADGRL2

Clone products for research

Alternative Splicing Database (ASD) splice patterns (SP) for ADGRL2 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b ^ 10a · 10b ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20a · 20b ^ 21 ^ 22a · 22b ^
SP1: - -
SP2: - -
SP3: - - -
SP4: - -
SP5:
SP6:
SP7:
SP8:
SP9:
SP10: - - - - - - - - - - - - - - - - - - - -
SP11:
SP12:
SP13:

ExUns: 23a · 23b · 23c ^ 24a · 24b ^ 25 ^ 26a · 26b · 26c ^ 27 ^ 28 ^ 29a · 29b · 29c · 29d
SP1: - - - - -
SP2: - - - - - - - -
SP3: - - - - - - - -
SP4: - - - - - - - - -
SP5: - - - - - - -
SP6: - - -
SP7: - - - -
SP8:
SP9: - - - - -
SP10: - - - - - - - - - - -
SP11: - - - - -
SP12:
SP13:

Relevant External Links for ADGRL2 Gene

GeneLoc Exon Structure for
ADGRL2

Expression for ADGRL2 Gene

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  1. Primer products for research
  2. Gene Expression Assays for research

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ADGRL2 Gene

mRNA expression in normal human tissues for ADGRL2 Gene
mRNA expression by GTEx for ADGRL2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for ADGRL2 Gene

This gene is overexpressed in Placenta (12.2), Gallbladder (11.4), and Fetal Brain (6.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for ADGRL2 Gene



Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ADGRL2

mRNA Expression by UniProt/SwissProt for ADGRL2 Gene:

O95490-AGRL2_HUMAN
Tissue specificity: Expressed very widely in all normal tissues tested. Expression is variable in tumor cell lines, apparently elevated in some lines and absent or markedly reduced in others.

Evidence on tissue expression from TISSUES for ADGRL2 Gene

  • Nervous system(4.7)
  • Liver(4.5)
  • Lung(2.5)
  • Kidney(2.4)
  • Heart(2.3)
  • Spleen(2.2)
  • Muscle(2.1)
  • Thyroid gland(2.1)
genes like me logo Genes that share expression patterns with ADGRL2: view

Primer products for research

No data available for mRNA differential expression in normal tissues , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for ADGRL2 Gene

Orthologs for ADGRL2 Gene

This gene was present in the common ancestor of animals.

Orthologs for ADGRL2 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
 Mammalia LPHN2 30 31
  • 99.74 (n)
 OneToOne
Cow
(Bos Taurus)
 Mammalia LPHN2 30 31
  • 94.54 (n)
 OneToOne
Dog
(Canis familiaris)
 Mammalia LPHN2 30 31
  • 93.8 (n)
 OneToOne
Platypus
(Ornithorhynchus anatinus)
 Mammalia oan-mir-7431 31
  • 90 (a)
 OneToOne
Oppossum
(Monodelphis domestica)
 Mammalia LPHN2 31
  • 90 (a)
 OneToOne
Mouse
(Mus musculus)
 Mammalia Lphn2 30 31
  • 87.41 (n)
 OneToOne
Adgrl2 17
Rat
(Rattus norvegicus)
 Mammalia Lphn2 30
  • 86.77 (n)
Chicken
(Gallus gallus)
 Aves LPHN2 30 31
  • 85.97 (n)
 OneToOne
Lizard
(Anolis carolinensis)
 Reptilia LPHN2 31
  • 90 (a)
 OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
 Amphibia lphn2 30
  • 81.53 (n)
Str.1058 30
African clawed frog
(Xenopus laevis)
 Amphibia Xl.16778 30
Zebrafish
(Danio rerio)
 Actinopterygii CABZ01074906.1 31
  • 74 (a)
 ManyToMany
lphn2a 30 31
  • 71.06 (n)
 ManyToMany
CU467642.1 31
  • 71 (a)
 ManyToMany
CABZ01096573.1 31
  • 54 (a)
 ManyToMany
FP245444.1 31
  • 46 (a)
 ManyToMany
wufb72a08 30
Worm
(Caenorhabditis elegans)
 Secernentea lat-1 30 31
  • 45.4 (n)
 OneToMany
Species where no ortholog for ADGRL2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)

Evolution for ADGRL2 Gene

ENSEMBL:
Gene Tree for ADGRL2 (if available)
TreeFam:
Gene Tree for ADGRL2 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for ADGRL2: view image

Paralogs for ADGRL2 Gene

Variants for ADGRL2 Gene

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Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ADGRL2 Gene

SNP ID Clinical significance and condition Chr 01 pos Variation AA Info Type
rs1323036742 Likely Benign: not provided 81,950,367(+) A/G
NM_012302.4(ADGRL2):c.1377A>G (p.Thr459=) 		SYNONYMOUS
rs141619218 Likely Benign: not provided 81,952,012(+) A/G
NM_012302.4(ADGRL2):c.1652A>G (p.Lys551Arg) 		MISSENSE
rs190474171 Likely Benign: not provided 81,966,555(+) G/A
NM_012302.4(ADGRL2):c.2244G>A (p.Glu748=) 		SYNONYMOUS
rs61741047 Benign: not provided 81,990,617(+) G/A
NM_012302.4(ADGRL2):c.3684G>A (p.Thr1228=) 		SYNONYMOUS_VARIANT,THREE_PRIME_UTR
VAR_077836 - p.Arg467Thr

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for ADGRL2 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for ADGRL2 Gene

Variant ID Type Subtype PubMed ID
esv1159587 CNV deletion 17803354
esv2659412 CNV deletion 23128226
esv3307207 CNV mobile element insertion 20981092
esv3308604 CNV mobile element insertion 20981092
esv3323603 CNV insertion 20981092
esv3380260 CNV insertion 20981092
esv3564837 CNV deletion 23714750
esv3577986 CNV loss 25503493
esv3586619 CNV loss 21293372
esv3586621 CNV loss 21293372
esv3586622 CNV gain 21293372
esv3586623 CNV loss 21293372
esv3586624 CNV loss 21293372
nsv437226 CNV loss 16327808
nsv437590 CNV loss 16327808
nsv473455 CNV novel sequence insertion 20440878
nsv506937 OTHER sequence alteration 20534489
nsv823331 CNV loss 20364138
nsv830359 CNV gain 17160897
nsv946023 CNV duplication 23825009

Variation tolerance for ADGRL2 Gene

Residual Variation Intolerance Score: 10.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.70; 66.14% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ADGRL2 Gene

Human Gene Mutation Database (HGMD)
ADGRL2
SNPedia medical, phenotypic, and genealogical associations of SNPs for
ADGRL2

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ADGRL2 Gene

Disorders for ADGRL2 Gene

MalaCards: The human disease database

(3) MalaCards diseases for ADGRL2 Gene - From: COP and GCD

Disorder Aliases PubMed IDs
rhombencephalosynapsis
robinow syndrome, autosomal recessive 1
  • rrs1
microcephaly
  • microcephalus
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for ADGRL2

Atlas
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
Open Targets Platform
genes like me logo Genes that share disorders with ADGRL2: view

No data available for UniProtKB/Swiss-Prot and Genatlas for ADGRL2 Gene

Publications for ADGRL2 Gene

  1. International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors. (PMID: 25713288) Hamann J … Schiöth HB (Pharmacological reviews 2015) 2 3 4
  2. Genomic structure and expression profile of LPHH1, a 7TM gene variably expressed in breast cancer cell lines. (PMID: 10760572) White GR … Heighway J (Biochimica et biophysica acta 2000) 2 3 4
  3. Isolation and characterization of a human homologue of the latrophilin gene from a region of 1p31.1 implicated in breast cancer. (PMID: 10030676) White GR … Heighway J (Oncogene 1998) 3 4 23
  4. Discovery of tissue-specific exons using comprehensive human exon microarrays. (PMID: 17456239) Clark TA … Blume JE (Genome biology 2007) 3 4
  5. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory SG … Prigmore E (Nature 2006) 3 4

ExternalLinks

View latest publications for ADGRL2 gene in Mastermind

Products for ADGRL2 Gene

Sources for ADGRL2 Gene