Aliases for ADGRG4 Gene
External Ids for ADGRG4 Gene
Previous HGNC Symbols for ADGRG4 Gene
This gene encodes a G-protein coupled receptor belonging to a large family of diverse integral membrane proteins that participate in various physiological functions. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The ligand for this family member is unknown, and it is therefore an orphan receptor. This receptor is known to be expressed in normal enterochromaffin cells and in gastrointestinal neuroendocrine carcinoma cells, and it is therefore considered to be a novel biomarker or target for immunotherapy. [provided by RefSeq, May 2010]
GeneCards Summary for ADGRG4 Gene
ADGRG4 (Adhesion G Protein-Coupled Receptor G4) is a Protein Coding gene. Diseases associated with ADGRG4 include Neuroendocrine Carcinoma and Mental Retardation, X-Linked, Syndromic, Martin-Probst Type. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and transmembrane signaling receptor activity. An important paralog of this gene is ADGRG6.
UniProtKB/Swiss-Prot Summary for ADGRG4 Gene