Aliases for ADGRG3 Gene
External Ids for ADGRG3 Gene
Previous HGNC Symbols for ADGRG3 Gene
GeneCards Summary for ADGRG3 Gene
ADGRG3 (Adhesion G Protein-Coupled Receptor G3) is a Protein Coding gene. Diseases associated with ADGRG3 include Polymicrogyria, Bilateral Frontoparietal. Among its related pathways are Innate Immune System. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and transmembrane signaling receptor activity. An important paralog of this gene is ADGRG1.
UniProtKB/Swiss-Prot Summary for ADGRG3 Gene
Orphan receptor that regulates migration of lymphatic endothelial cells in vitro via the small GTPases RhoA and CDC42 (PubMed:24178298). Regulates B-cell development (By similarity). Seems to signal through G-alpha(q)-proteins (PubMed:22575658).