Aliases for ADGRG2 Gene
External Ids for ADGRG2 Gene
Previous HGNC Symbols for ADGRG2 Gene
This gene encodes a member of the G protein-coupled receptor family described as an epididymis-specific transmembrane protein. The encoded protein may be proteolytically processed as it contains a motif shown to be a protein scission motif in some members of this family (PMID: 11973329). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
GeneCards Summary for ADGRG2 Gene
ADGRG2 (Adhesion G Protein-Coupled Receptor G2) is a Protein Coding gene. Diseases associated with ADGRG2 include Vas Deferens, Congenital Bilateral Aplasia Of, X-Linked and Vas Deferens, Congenital Bilateral Aplasia Of. Among its related pathways are GPCRs, Class B Secretin-like. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and transmembrane signaling receptor activity. An important paralog of this gene is ADGRG6.
UniProtKB/Swiss-Prot for ADGRG2 Gene
Orphan receptor. Could be involved in a signal transduction pathway controlling epididymal function and male fertility. May regulate fluid exchange within epididymis.