Aliases for ADGRB3 Gene
External Ids for ADGRB3 Gene
Previous HGNC Symbols for ADGRB3 Gene
This p53-target gene encodes a brain-specific angiogenesis inhibitor, a seven-span transmembrane protein, and is thought to be a member of the secretin receptor family. Brain-specific angiogenesis proteins BAI2 and BAI3 are similar to BAI1 in structure, have similar tissue specificities, and may also play a role in angiogenesis. [provided by RefSeq, Jul 2008]
GeneCards Summary for ADGRB3 Gene
ADGRB3 (Adhesion G Protein-Coupled Receptor B3) is a Protein Coding gene. Diseases associated with ADGRB3 include Hidradenoma. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and transmembrane signaling receptor activity. An important paralog of this gene is ADGRB2.
UniProtKB/Swiss-Prot Summary for ADGRB3 Gene
Receptor that plays a role in the regulation of synaptogenesis and dendritic spine formation at least partly via interaction with ELMO1 and RAC1 activity (By similarity). Promotes myoblast fusion through ELMO/DOCK1 (PubMed:24567399).