Aliases for ADGRA2 Gene
External Ids for ADGRA2 Gene
Previous HGNC Symbols for ADGRA2 Gene
GeneCards Summary for ADGRA2 Gene
ADGRA2 (Adhesion G Protein-Coupled Receptor A2) is a Protein Coding gene. Among its related pathways are Integrins in angiogenesis. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and transmembrane signaling receptor activity. An important paralog of this gene is ADGRA3.
UniProtKB/Swiss-Prot for ADGRA2 Gene
Endothelial receptor which functions as a WNT7-specific coactivator of canonical Wnt signaling (By similarity). Required for normal endothelial cell sprouting and migration in the forebrain and neural tube (By similarity). Has a major role in establishing the blood-brain barrier (By similarity). Binds to the glycosaminoglycans heparin, heparin sulfate, chondroitin sulfate and dermatan sulfate (PubMed:16982628).