Aliases for ADCK1 Gene
External Ids for ADCK1 Gene
Previous GeneCards Identifiers for ADCK1 Gene
GeneCards Summary for ADCK1 Gene
ADCK1 (AarF Domain Containing Kinase 1) is a Protein Coding gene. Diseases associated with ADCK1 include Coenzyme Q10 Deficiency, Primary, 4 and Coenzyme Q10 Deficiency Disease. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein serine/threonine kinase activity. An important paralog of this gene is ADCK5.
UniProtKB/Swiss-Prot Summary for ADCK1 Gene
Appears to be essential for maintaining mitochondrial cristae formation and mitochondrial function by acting via YME1L1 in a kinase-independent manner to regulate essential mitochondrial structural proteins OPA1 and IMMT (PubMed:31125351). The action of this enzyme is not yet clear (Probable). It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr) (Probable).